Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Sandeep Bhosale"'
Publikováno v:
Molecules, Vol 29, Iss 20, p 4870 (2024)
Glycoside hydrolases have been implicated in a wide range of human conditions including lysosomal storage diseases. Consequently, many researchers have directed their efforts towards identifying new classes of glycoside hydrolase inhibitors, both syn
Externí odkaz:
https://doaj.org/article/b22d705092f045858673c53a8b27fbd2
Publikováno v:
International Journal of Advanced Research in Science, Communication and Technology. :46-50
Increased internet and cell phone use over the past 20 years has altered how people communicate and conduct business. E-commerce is a new idea and a game changer for businesses everywhere. The e-commerce industry is predicted to develop at a 41% CAGR
Autor:
Oluwafemi Akintola, Marco Farren-Dai, Weiwu Ren, Sandeep Bhosale, Robert Britton, Katarzyna Świderek, Vicent Moliner, Andrew J. Bennet
Publikováno v:
ACS Catalysis. 12:14667-14678
Autor:
Pal John Pal Adabala, Yang Wang, Oluwafemi S. Akintola, Sandeep Bhosale, Robert Britton, Weiwu Ren, Yumeela Ganga-Sah, Andrew J. Bennet
Publikováno v:
ACS Catalysis. 11:9377-9389
Autor:
Matthew C. Deen, Yanping Zhu, Christina Gros, Na Na, Pierre-André Gilormini, David L. Shen, Sandeep Bhosale, Nadia Anastasi, RuiQi Wang, Xiaoyang Shan, Eva Harde, Ravi Jagasia, Francis C. Lynn, David J. Vocadlo
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Loss of activity of the lysosomal glycosidase β-glucocerebrosidase (GCase) causes the lysosomal storage disease Gaucher disease (GD) and has emerged as the greatest genetic risk factor for the development of both Parkinson disease (PD) and dementia
Autor:
Kapil Mestry, Pratik Mahajan, Harshavardhini Jagadale, Sandeep Bhosale, Deepak Gundecha, Siddheswar Saha, Manas Koner
Publikováno v:
SAE Technical Paper Series.
Autor:
Summon Koul, Suresh Kurhade, Sandeep Bhosale, Keshav Naik, Videsh Salunkhe, Sudhir Ravula, Prasad Punde, Ravikumar Velayutham, Atul Tiwari, Daniela Ahl, Srividya Malkapuram, Vamsi Mudagala, Amol Raje, Dhananjay Umrani, Suhas Tambe, Poonam Patil, Umesh Singh, Debnath Bhuniya, Narayanan Hariharan, Kasim Mookhtiar
Publikováno v:
Bioorganicmedicinal chemistry letters. 62
A series of novel spirocyclic DGAT1 inhibitors containing the oxadiazole motif were designed and synthesized for biological evaluation. Several compounds exhibited potent diacylglycerol acyltransferase 1 (DGAT1) inhibitory activity. Optimization of t
Autor:
Ashwinkumar V. Meru, Siddhartha De, Debnath Bhuniya, Nadim S. Shaikh, Kasim A. Mookhtiar, Kaushal Joshi, Rashmi Barbhaiya, Vamsi Madgula, Sandeep Bhosale, Amol A. Raje, Rajendra K. Kharul, Dhananjay Joshi, Amol Magdum, Fouzia Begum, Sonalee Athavankar, Hajare Atul Kashinath, Sandip Balwe
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 29:238-243
Conceptual design and modification of urea moiety in chemotype PF-3845/04457845, the bench marking irreversible inhibitor of fatty acid amide hydrolase (FAAH), led to discovery of a novel nicotinamide-based lead 12a having reversible mechanism of act
Autor:
Andrew J. Bennet, Pal John Pal Adabala, Oluwafemi S. Akintola, Sandeep Bhosale, Saeideh Shamsi Kazem Abadi
Publikováno v:
The Journal of organic chemistry. 85(5)
Glycoside hydrolases (GHs) catalyze hydrolyses of glycoconjugates in which the enzyme choreographs a series of conformational changes during the catalytic cycle. As a result, some GH families, including α-amylases (GH13), have their chemical steps c
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:2285-2288
A new class of isoxazole-tethered diarylheptanoids having characteristic 1,3-syn-diol and 1,3-anti-diol chemophoric moieties, e.g. 4a–d and 5a–c respectively, have been designed and synthesized starting from d -glucose following a stereo-conserve