Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sandeep Bhosale"'
Publikováno v:
Molecules, Vol 29, Iss 20, p 4870 (2024)
Glycoside hydrolases have been implicated in a wide range of human conditions including lysosomal storage diseases. Consequently, many researchers have directed their efforts towards identifying new classes of glycoside hydrolase inhibitors, both syn
Externí odkaz:
https://doaj.org/article/b22d705092f045858673c53a8b27fbd2
Publikováno v:
International Journal of Advanced Research in Science, Communication and Technology. :46-50
Increased internet and cell phone use over the past 20 years has altered how people communicate and conduct business. E-commerce is a new idea and a game changer for businesses everywhere. The e-commerce industry is predicted to develop at a 41% CAGR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d618684afd57ac5e291479a900c7de2
https://doi.org/10.48175/ijarsct-8109
https://doi.org/10.48175/ijarsct-8109
Autor:
Oluwafemi Akintola, Marco Farren-Dai, Weiwu Ren, Sandeep Bhosale, Robert Britton, Katarzyna Świderek, Vicent Moliner, Andrew J. Bennet
Publikováno v:
ACS Catalysis. 12:14667-14678
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31e0d62d78af97ecd034fb18e4256abd
https://doi.org/10.1021/acscatal.2c04027
https://doi.org/10.1021/acscatal.2c04027
Autor:
Pal John Pal Adabala, Yang Wang, Oluwafemi S. Akintola, Sandeep Bhosale, Robert Britton, Weiwu Ren, Yumeela Ganga-Sah, Andrew J. Bennet
Publikováno v:
ACS Catalysis. 11:9377-9389
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54a6869e0e41b070c1e7f0f6ae48f6cc
https://doi.org/10.1021/acscatal.1c01634
https://doi.org/10.1021/acscatal.1c01634
Autor:
Matthew C. Deen, Yanping Zhu, Christina Gros, Na Na, Pierre-André Gilormini, David L. Shen, Sandeep Bhosale, Nadia Anastasi, RuiQi Wang, Xiaoyang Shan, Eva Harde, Ravi Jagasia, Francis C. Lynn, David J. Vocadlo
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Loss of activity of the lysosomal glycosidase β-glucocerebrosidase (GCase) causes the lysosomal storage disease Gaucher disease (GD) and has emerged as the greatest genetic risk factor for the development of both Parkinson disease (PD) and dementia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0113bca08bd05ac62b44bc1768f3cf2a
https://doi.org/10.1073/pnas.2200553119
https://doi.org/10.1073/pnas.2200553119
Autor:
Kapil Mestry, Pratik Mahajan, Harshavardhini Jagadale, Sandeep Bhosale, Deepak Gundecha, Siddheswar Saha, Manas Koner
Publikováno v:
SAE Technical Paper Series.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3d2740dbb32f88532eb6355df3bf06c
https://doi.org/10.4271/2022-01-0629
https://doi.org/10.4271/2022-01-0629
Autor:
Summon Koul, Suresh Kurhade, Sandeep Bhosale, Keshav Naik, Videsh Salunkhe, Sudhir Ravula, Prasad Punde, Ravikumar Velayutham, Atul Tiwari, Daniela Ahl, Srividya Malkapuram, Vamsi Mudagala, Amol Raje, Dhananjay Umrani, Suhas Tambe, Poonam Patil, Umesh Singh, Debnath Bhuniya, Narayanan Hariharan, Kasim Mookhtiar
Publikováno v:
Bioorganicmedicinal chemistry letters. 62
A series of novel spirocyclic DGAT1 inhibitors containing the oxadiazole motif were designed and synthesized for biological evaluation. Several compounds exhibited potent diacylglycerol acyltransferase 1 (DGAT1) inhibitory activity. Optimization of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8687566935fcb2ba4d51bfa986746836
https://pubmed.ncbi.nlm.nih.gov/35189320
https://pubmed.ncbi.nlm.nih.gov/35189320
Autor:
Ashwinkumar V. Meru, Siddhartha De, Debnath Bhuniya, Nadim S. Shaikh, Kasim A. Mookhtiar, Kaushal Joshi, Rashmi Barbhaiya, Vamsi Madgula, Sandeep Bhosale, Amol A. Raje, Rajendra K. Kharul, Dhananjay Joshi, Amol Magdum, Fouzia Begum, Sonalee Athavankar, Hajare Atul Kashinath, Sandip Balwe
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 29:238-243
Conceptual design and modification of urea moiety in chemotype PF-3845/04457845, the bench marking irreversible inhibitor of fatty acid amide hydrolase (FAAH), led to discovery of a novel nicotinamide-based lead 12a having reversible mechanism of act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee8afc28b56fce6740f7cbc39ee182d1
https://doi.org/10.1016/j.bmcl.2018.11.048
https://doi.org/10.1016/j.bmcl.2018.11.048
Autor:
Andrew J. Bennet, Pal John Pal Adabala, Oluwafemi S. Akintola, Sandeep Bhosale, Saeideh Shamsi Kazem Abadi
Publikováno v:
The Journal of organic chemistry. 85(5)
Glycoside hydrolases (GHs) catalyze hydrolyses of glycoconjugates in which the enzyme choreographs a series of conformational changes during the catalytic cycle. As a result, some GH families, including α-amylases (GH13), have their chemical steps c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9389cf8bcc69041790b9894988e1486
https://pubmed.ncbi.nlm.nih.gov/31994882
https://pubmed.ncbi.nlm.nih.gov/31994882
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:2285-2288
A new class of isoxazole-tethered diarylheptanoids having characteristic 1,3-syn-diol and 1,3-anti-diol chemophoric moieties, e.g. 4a–d and 5a–c respectively, have been designed and synthesized starting from d -glucose following a stereo-conserve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae16ff39e59bc9ba2f71a728bf8922d1
https://doi.org/10.1016/j.bmcl.2018.05.032
https://doi.org/10.1016/j.bmcl.2018.05.032