Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sandani Samarajeewa"'
Autor:
Deborah H. Sultan, Steven L. Brody, Simcha E. Felder, Tianyi Cai, Kvar C. L. Black, Yuefei Shen, Aida Ibricevic, Karen L. Wooley, Ann-Kathrin Löbs, Sean P. Gunsten, Jeniree A. Flores, Jeffery E. Raymond, Tiffany P. Gustafson, Yongjian Liu, Sandani Samarajeewa, Mikhail Y. Berezin, Natalia G. Zhegalova, Ritu Shrestha
Publikováno v:
Biomaterials. 98:53-63
Nanoparticles (NPs) play expanding roles in biomedical applications including imaging and therapy, however, their long-term fate and clearance profiles have yet to be fully characterized in vivo. NP delivery via the airway is particularly challenging
Autor:
Mahmoud Elsabahy, Ritu Shrestha, Sandani Samarajeewa, Stephanie Florez-Malaver, Karen L. Wooley
Publikováno v:
Biomaterials. 33:8557-8568
Cationic shell crosslinked knedel-like nanoparticles (cSCKs) have emerged as a highly efficient transfection agent for nucleic acids delivery. In this study, a new class of cSCKs with tunable buffering capacities has been developed by altering the am
Publikováno v:
Journal of the American Chemical Society. 134:1235-1242
Comparative studies of bulk samples of hydrolytically degradable poly(lactic acid) (PLA) vs core-shell block copolymer micelles having PLA cores revealed remarkable acceleration in the proteinase K enzymatic hydrolysis of the nanoparticulate forms an
Autor:
Sean P. Gunsten, Mahmoud Elsabahy, Steven L. Brody, Sandani Samarajeewa, Karen L. Wooley, Ritu Shrestha, Aida Ibricevic
Publikováno v:
Biomacromolecules. 14(4)
In this work, degradable cationic shell cross-linked knedel-like (deg-cSCK) nanoparticles were developed as an alternative platform to replace similar nondegradable cSCK nanoparticles that have been utilized for nucleic acids delivery. An amphiphilic
Autor:
Karen L. Wooley, Richard B. Dorshow, Ryan P. Zentay, Ang Li, Amolkumar Karwa, Mahmoud Elsabahy, Ritu Shrestha, Sandani Samarajeewa, James G. Kostelc
Publikováno v:
Molecular pharmaceutics. 10(3)
Paclitaxel-loaded shell cross-linked polymeric nanoparticles having an enzymatically and hydrolytically degradable poly(lactic acid) core and a glutathione-responsive disulfide cross-linked poly(oligoethylene glycol)-containing corona were constructe
Autor:
Karen L. Wooley, Michael J. Welch, Yongjian Liu, Jiong Zou, Ang Li, Shiyi Zhang, Sandani Samarajeewa, Fuwu Zhang, Guorong Sun, Hannah Luehmann
Publikováno v:
ACS nano. 6(10)
Nanoparticles with tunable pharmacokinetics are desirable for various biomedical applications. Poly(ethylene glycol) (PEG) is well known to create “stealth” effects to stabilize and extend the blood circulation of nanoparticles. In this work, pol
Synthetic asymmetrical systems, Janus particles and patchy particles, are capable of undergoing hierarchical assembly processes that mimic those of Nature, to serve as switchable devices, optical probes, phase-transfer catalysts, and multifunctional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8032e1a6f7f1265040e7a34d66c887d
https://europepmc.org/articles/PMC3148585/
https://europepmc.org/articles/PMC3148585/
Autor:
Robert Harwell, Sharath R. Kirumakki, Atashi Mukherjee, Sandani Samarajeewa, Abraham Clearfield, Rolfe H. Herber
Publikováno v:
ChemInform. 40
We have designed a new family of layered Sn(iv)phosphonate (SnPP) materials which are very efficient catalysts in the BV oxidation of aromatic aldehydes without any solvent and using aqueous H(2)O(2) (30%) as the oxidant.
Autor:
Sharath R. Kirumakki, Abraham Clearfield, Atashi Mukherjee, Robert Harwell, Rolfe H. Herber, Sandani Samarajeewa
Publikováno v:
Chemical communications (Cambridge, England). (43)
We have designed a new family of layered Sn(iv)phosphonate (SnPP) materials which are very efficient catalysts in the BV oxidation of aromatic aldehydes without any solvent and using aqueous H(2)O(2) (30%) as the oxidant.
Publikováno v:
Journal of Materials Chemistry B. 1:5241
The development of stable nanoparticles that can withstand the changing conditions experienced in a biological setting and also be of low toxicity and immunogenicity is of particular importance to address the problems associated with currently utiliz