Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Sanda Iacobas"'
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 3, Pp 2355-2385 (2024)
Low-salt diet (LSD) is a constant recommendation to hypertensive patients, but the genomic mechanisms through which it improves cardiac pathophysiology are still not fully understood. Our publicly accessible transcriptomic dataset of the left ventric
Externí odkaz:
https://doaj.org/article/94901d09412f4896aa657580d58536fd
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 12, Pp 9471-9499 (2023)
Clear cell renal cell carcinoma (ccRCC) is the most frequent form of kidney cancer. Metastatic stages of ccRCC reduce the five-year survival rate to 15%. In this report, we analyze the ccRCC-induced remodeling of the five KEGG-constructed excretory f
Externí odkaz:
https://doaj.org/article/5c1771a9a6664041b3ccb1f8ec367c2b
Autor:
Dumitru Andrei Iacobas, Sanda Iacobas
Publikováno v:
Genes, Vol 15, Iss 5, p 621 (2024)
The genetic causes of the differentiated, highly treatable, and mostly non-fatal papillary thyroid cancer (PTC) are not yet fully understood. The mostly accepted PTC etiology blames the altered sequence or/and expression level of certain biomarker ge
Externí odkaz:
https://doaj.org/article/0391193b69ac465692c756bb18bb3a21
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 6, Pp 4850-4874 (2023)
The high morbidity and mortality rate of pulmonary arterial hypertension (PAH) is partially explained by metabolic deregulation. The present study complements our previous publication in “Genes” by identifying significant increases of the glucose
Externí odkaz:
https://doaj.org/article/6ca1675324ab4d858c75a100eb531ed8
Autor:
Sanda Iacobas, Dumitru Andrei Iacobas
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 1, Pp 360-382 (2022)
Many years and billions spent for research did not yet produce an effective answer to prostate cancer (PCa). Not only each human, but even each cancer nodule in the same tumor, has unique transcriptome topology. The differences go beyond the expressi
Externí odkaz:
https://doaj.org/article/805d58cc948c470f9f6d0babe98dfb1e
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-20 (2021)
Abstract Myocardium transcriptomes of left and right atria and ventricles from four adult male C57Bl/6j mice were profiled with Agilent microarrays to identify the differences responsible for the distinct functional roles of the four heart chambers.
Externí odkaz:
https://doaj.org/article/431fbd67d01f40adbe625ea726fe307e
Autor:
Lindice M. Nisimura, Laura L. Coelho, Tatiana G. de Melo, Paloma de Carvalho Vieira, Pedro H. Victorino, Luciana R. Garzoni, David C. Spray, Dumitru A. Iacobas, Sanda Iacobas, Herbert B. Tanowitz, Daniel Adesse
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Chagas disease is responsible for more than 10,000 deaths per year and about 6 to 7 million infected people worldwide. In its chronic stage, patients can develop mega-colon, mega-esophagus, and cardiomyopathy. Differences in clinical outcomes may be
Externí odkaz:
https://doaj.org/article/8d5c0668d6294b36980734a44734049d
Publikováno v:
Genes, Vol 12, Iss 8, p 1172 (2021)
Neuropsychiatric manifestations of systemic lupus erythematosus (SLE), specifically cognitive dysfunction and mood disorders, are widely prevalent in SLE patients, and yet poorly understood. TNF-like weak inducer of apoptosis (TWEAK) has previously b
Externí odkaz:
https://doaj.org/article/9fdd8ca524014dc9ba6a24912fc85325
Autor:
Sanda Iacobas, Dumitru A. Iacobas
Publikováno v:
Cells, Vol 10, Iss 7, p 1644 (2021)
Decades of research identified genomic similarities among prostate cancer patients and proposed general solutions for diagnostic and treatments. However, each human is a dynamic unique with never repeatable transcriptomic topology and no gene therapy
Externí odkaz:
https://doaj.org/article/14ca92ff90174314a44c6d710b582eb9
Autor:
Pedro Henrique Victorino, Camila Marra, Dumitru Andrei Iacobas, Sanda Iacobas, David C. Spray, Rafael Linden, Daniel Adesse, Hilda Petrs-Silva
Publikováno v:
Genes, Vol 12, Iss 3, p 403 (2021)
Glaucoma is a multifactorial neurodegenerative disease, characterized by degeneration of the retinal ganglion cells (RGCs). There has been little progress in developing efficient strategies for neuroprotection in glaucoma. We profiled the retina tran
Externí odkaz:
https://doaj.org/article/b5be9afbc7a546bfb4675ce39c70422f