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DNA origami vaccine (DoriVac) nanoparticles improve both humoral and cellular immune responses to infectious diseases.

Autor: Zeng YC; Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA.; Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts 02115, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA., Young OJ; Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts 02115, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA.; Harvard-Massachusetts Institute of Technology (MIT) Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, USA., Si L; Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts 02115, USA., Ku MW; Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts 02115, USA., Isinelli G; Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts 02115, USA., Rajwar A; Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts 02115, USA., Jiang A; Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts 02115, USA., Wintersinger CM; Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA., Graveline AR; Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts 02115, USA., Vernet A; Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts 02115, USA., Sanchez M; Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts 02115, USA., Ryu JH; Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA.; Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea., Kwon IC; Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA.; Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea.; KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul 02841, Republic of Korea., Goyal G; Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts 02115, USA., Ingber DE; Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts 02115, USA.; Vascular Biology Program, Department of Surgery, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA.; Harvard John A. Paulson School of Engineering and Applied Sciences, Cambridge, MA, USA., Shih WM; Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA.; Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts 02115, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jan 02. Date of Electronic Publication: 2024 Jan 02.