Cellular density-dependent down-regulation of EP4 prostanoid receptors via the up-regulation of hypoxia-inducible factor-1 α in HCA-7 human colon cancer cells.

Autor: Otake, Sho, Yoshida, Kenji, Seira, Naofumi, Sanchez, Christopher M., Regan, John W., Fujino, Hiromichi, Murayama, Toshihiko

Publikováno v: Pharmacology Research & Perspectives; Feb2015, Vol. 3 Issue 1, pn/a-N.PAG, 13p

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Cellular density-dependent down-regulation of EP4 prostanoid receptors via the up-regulation of hypoxia-inducible factor-1α in HCA-7 human colon cancer cells.

Autor: Otake S; Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University Chuo-ku, Chiba, 260-8675, Japan., Yoshida K; Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University Chuo-ku, Chiba, 260-8675, Japan., Seira N; Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University Chuo-ku, Chiba, 260-8675, Japan., Sanchez CM; Department of Pharmacology & Toxicology, College of Pharmacy, The University of Arizona Tucson, Arizona, 85721-0207., Regan JW; Department of Pharmacology & Toxicology, College of Pharmacy, The University of Arizona Tucson, Arizona, 85721-0207., Fujino H; Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University Chuo-ku, Chiba, 260-8675, Japan., Murayama T; Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University Chuo-ku, Chiba, 260-8675, Japan.

Publikováno v: Pharmacology research & perspectives [Pharmacol Res Perspect] 2015 Feb; Vol. 3 (1), pp. e00083. Date of Electronic Publication: 2014 Nov 07.