Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sanaz Manteghi"'
Autor:
Sanaz Manteghi, Marie-Claude Gingras, Dmitri Kharitidi, Luc Galarneau, Maud Marques, Ming Yan, Regina Cencic, Francis Robert, Marilène Paquet, Michael Witcher, Jerry Pelletier, Arnim Pause
Publikováno v:
Cell Reports, Vol 15, Iss 9, Pp 1893-1900 (2016)
Endosomal sorting complexes required for transport (ESCRT) drive cell surface receptor degradation resulting in attenuation of oncogenic signaling and pointing to a tumor suppressor function. Here, we show that loss of function of an ESCRT protein (H
Externí odkaz:
https://doaj.org/article/20c7418fb9944e4c9e74f85af9af9e62
Autor:
Dmitri Kharitidi, Pirjo M. Apaja, Sanaz Manteghi, Kei Suzuki, Elena Malitskaya, Ariel Roldan, Marie-Claude Gingras, Junichi Takagi, Gergely L. Lukacs, Arnim Pause
Publikováno v:
Cell Reports, Vol 13, Iss 3, Pp 599-609 (2015)
Membrane trafficking of integrins plays a pivotal role in cell proliferation and migration. How endocytosed integrins are targeted either for recycling or lysosomal delivery is not fully understood. Here, we show that fibronectin (FN) binding to α5
Externí odkaz:
https://doaj.org/article/1e10c0e967634d08996299c6e5f36acf
Autor:
Elite Possik, Andrew Ajisebutu, Sanaz Manteghi, Marie-Claude Gingras, Tarika Vijayaraghavan, Mathieu Flamand, Barry Coull, Kathrin Schmeisser, Thomas Duchaine, Maurice van Steensel, David H Hall, Arnim Pause
Publikováno v:
PLoS Genetics, Vol 11, Iss 10, p e1005520 (2015)
Mechanisms of adaptation to environmental changes in osmolarity are fundamental for cellular and organismal survival. Here we identify a novel osmotic stress resistance pathway in Caenorhabditis elegans (C. elegans), which is dependent on the metabol
Externí odkaz:
https://doaj.org/article/5b4735d582f84756839b416b31cd3182
Autor:
Jerry Pelletier, Maud Marques, Sanaz Manteghi, Regina Cencic, Marilène Paquet, Ming Yan, Luc Galarneau, Arnim Pause, Michael Witcher, Francis Robert, Dmitri Kharitidi, Marie-Claude Gingras
Publikováno v:
Cell Reports, Vol 15, Iss 9, Pp 1893-1900 (2016)
SummaryEndosomal sorting complexes required for transport (ESCRT) drive cell surface receptor degradation resulting in attenuation of oncogenic signaling and pointing to a tumor suppressor function. Here, we show that loss of function of an ESCRT pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01b995ab327a2b31ee3d2f7e2dc5fee0
https://doi.org/10.1016/j.celrep.2016.04.076
https://doi.org/10.1016/j.celrep.2016.04.076
Chronic AMPK activation via loss of FLCN induces functional beige adipose tissue through PGC-1α/ERRα
Autor:
Ming Yan, Masaya Baba, Benjamin Walker, Sanaz Manteghi, Vincent Giguère, Arnim Pause, Julie St-Pierre, Catherine R. Dufour, Étienne Audet-Walsh
Publikováno v:
Genes & Development. 30:1034-1046
The tumor suppressor folliculin (FLCN) forms a repressor complex with AMP-activated protein kinase (AMPK). Given that AMPK is a master regulator of cellular energy homeostasis, we generated an adipose-specific Flcn (Adipoq-FLCN) knockout mouse model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b07a5bbf6db649de7f7b6129564490e7
https://doi.org/10.1101/gad.281410.116
https://doi.org/10.1101/gad.281410.116
Autor:
Kei Suzuki, Arnim Pause, Marie-Claude Gingras, Junichi Takagi, Ariel Roldan, Pirjo M. Apaja, Sanaz Manteghi, Gergely L. Lukacs, Dmitri Kharitidi, Elena Malitskaya
Publikováno v:
Cell Reports, Vol 13, Iss 3, Pp 599-609 (2015)
SummaryMembrane trafficking of integrins plays a pivotal role in cell proliferation and migration. How endocytosed integrins are targeted either for recycling or lysosomal delivery is not fully understood. Here, we show that fibronectin (FN) binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa3695150fbc08f77cf515d6f4a8632e
Autor:
Sagi Abelson, John Douglas Mcpherson, Fouad Yousif, Sanaz Manteghi, Jian Chen, Johann K. Hitzler, Yue Li
Publikováno v:
Blood. 132:442-442
INTRODUCTION . Transient Leukemia (TL; also termed Transient Myeloproliferative disorder, TMD, and Transient Abnormal Myelopoiesis, TAM) occurs in 10-30% of newborns with Down syndrome (DS). Approx. 20% of infants with TL go on to develop acute myelo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::060aa7f852b2a6b23c881f936bfd6911
https://doi.org/10.1182/blood-2018-99-117198
https://doi.org/10.1182/blood-2018-99-117198
Autor:
Neda Vaseli-Hagh, Sanaz Manteghi, Pardis Khosravani, Abdolkhaleg Deezagi, Zahra-Soheila Soheili
Publikováno v:
Leukemia & Lymphoma. 50:1519-1527
The purpose of this research was to understand the effect of hyperthermia on the telomerase activity in human leukemic cell lines (HL-60, K562, and TF-1). The cells were treated by hyperthermia at the range of 41-44 degrees C for 120 min and incubate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::972268e88a2bd8a42134fffe45bf903d
https://doi.org/10.1080/10428190903129130
https://doi.org/10.1080/10428190903129130
Autor:
Barry J. Coull, Tarika Vijayaraghavan, Maurice A.M. van Steensel, Marie-Claude Gingras, Sanaz Manteghi, Elite Possik, Thomas F. Duchaine, Arnim Pause, David H. Hall, Kathrin Schmeisser, Andrew Ajisebutu, Mathieu N. Flamand
Publikováno v:
PLoS Genetics, Vol 11, Iss 10, p e1005520 (2015)
PLoS Genetics
PLoS Genetics
Mechanisms of adaptation to environmental changes in osmolarity are fundamental for cellular and organismal survival. Here we identify a novel osmotic stress resistance pathway in Caenorhabditis elegans (C. elegans), which is dependent on the metabol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbde789844834e74ad01da69ca8dcaea
http://europepmc.org/articles/PMC4595296?pdf=render
http://europepmc.org/articles/PMC4595296?pdf=render
Publikováno v:
Methods (San Diego, Calif.). 65(2)
Protein tyrosine phosphatases (PTPs) are key enzymes in the regulation of cellular homeostasis and signaling pathways. Strikingly, not all PTPs bear enzymatic activity. A considerable fraction of PTPs are enzymatically inactive and are known as pseud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5fc565bc0c49b9648cf02f5bae16018
https://pubmed.ncbi.nlm.nih.gov/24064037
https://pubmed.ncbi.nlm.nih.gov/24064037