TriOptimize VII: Improvement of health-related quality of life after 3 months treatmentwith extrafine single inhaler triple therapy in COPD patients in a real-world setting

Autor: Sanaz Bahari Javan, R Hövelmann, K. Melchior, C Geßner, George Georges, Carl-Peter Criée

Publikováno v: Airway pharmacology and treatment.

Introduction: TriOptimize is the first real-world (RW) study collecting data from patients treated with extrafine single inhaler triple therapy (efSITT). Here, we present an interim analysis of changes in health-related quality of life (HRQoL) after

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::63805b413a97553c6e3e7a073d3adbd7
https://doi.org/10.1183/13993003.congress-2020.978

Formin 2 links neuropsychiatric phenotypes at young age to an increased risk for dementia

Autor: Andrea Schmitt, Nelson Rebola, Susanne Burkhardt, Christophe Mulle, Eva Benito, Ivana Delalle, Roberto Carlos Agis-Balboa, Alexander Jatzko, Gaurav Jain, Patricia A. Zunszain, Sanaz Bahari-Javan, Paulo S. Pinheiro, Julius C. Pape, Markus Dettenhofer, Peter Falkai, Michael Gertig, Farahnaz Sananbenesi, Cemil Kerimoglu, Elisabeth B. Binder, Andre Fischer

Publikováno v: Agís-Balboa, R C, Pinhero, P, Rebola, N, Kerimoglu, C, Benito, E, Gertig, M, Bahari-Javan, S, Jain, G, Burkhardt, S, Delalle, I, Jatzko, A, Dettenhofer, M, Zunszain, P A, Schmitt, A, Falkai, P, Pape, J C, Binder, E B, Mulle, C, Fischer, A & Sananbenesi, F 2017, ' Formin 2 links neuropsychiatric phenotypes at young age to an increased risk for dementia ', The EMBO journal, vol. 36, no. 19, pp. 2815-2828 . https://doi.org/10.15252/embj.201796821
The EMBO journal 36(19), 2815-2828 (2017). doi:10.15252/embj.201796821
RUNA. Repositorio da Consellería de Sanidade e Sergas
Servizo Galego de Saúde (SERGAS)
EMBO JOURNAL
The EMBO Journal

Age-associated memory decline is due to variable combinations of genetic and environmental risk factors. How these risk factors interact to drive disease onset is currently unknown. Here we begin to elucidate the mechanisms by which post-traumatic st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88c13c908d6e0f860de3484a7771db35
https://kclpure.kcl.ac.uk/ws/files/80023520/Formin_2_links_neuropsychiatric_AGILS_BALBOA_Publishedonline2August2017_GOLD_VoR_CC_BY_.pdf

DNA methylation changes in plasticity genes accompany the formation and maintenance of memory

Autor: Frauke van Bebber, Vincenzo Capece, Eva Benito, Magali Hennion, Ramon O. Vidal, Sanaz Bahari Javan, Orr Shomroni, Stefan Bonn, Christian Haass, Susanne Burkhardt, Ashish Rajput, Tonatiuh Pena Centeno, Rashi Halder, Julio C. Garcia Vizcaino, Andre Fischer, Magdalena Navarro Sala, Raza-Ur Rahman, Anna-Lena Schuetz, Bettina Schmid

Publikováno v: Nature reviews / Neuroscience 19(1), 102-110 (2016). doi:10.1038/nn.4194

The ability to form memories is a prerequisite for an organism's behavioral adaptation to environmental changes. At the molecular level, the acquisition and maintenance of memory requires changes in chromatin modifications. In an effort to unravel th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30e9af6097307419096d12871ff24691
https://pub.dzne.de/record/138297

The anaphase promoting complex is required for memory function in mice

Autor: Farahnaz Sananbenesi, Kim Nasmyth, Andre Fischer, Tanja Kuczera, Hung-En Hsia, Stefan Irniger, Roman M. Stilling, Sanaz Bahari-Javan

Publikováno v: Learning & Memory. 18:49-57

Learning and memory processes critically involve the orchestrated regulation of de novo protein synthesis. On the other hand it has become clear that regulated protein degradation also plays a major role in neuronal plasticity and learning behavior.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::943f6dc132d1eb95491e8edc6108a0fd
https://doi.org/10.1101/lm.1998411

Histone-acetylation: a link between Alzheimer's disease and post-traumatic stress disorder?

Autor: Andre Fischer, Sanaz Bahari-Javan, Farahnaz Sananbenesi

Publikováno v: Frontiers in Neuroscience
Frontiers in neuroscience 8, 160 (2014). doi:10.3389/fnins.2014.00160
Frontiers in Neuroscience, Vol 8 (2014)

The orchestration of gene-expression programs is essential for cellular homeostasis. Epigenetic processes provide to the cell a key mechanism that allows the regulation of gene-expression networks in response to environmental stimuli. Recently epigen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea78cd16d5540b0e038c1e40524d9b4a
https://pubmed.ncbi.nlm.nih.gov/25009454