Guidance document on the impact of water treatment processes on residues of active substances or their metabolites in water abstracted for the production of drinking water

Autor: European Chemicals Agency (ECHA) and European Food Safety Authority (EFSA), Roberta Hofman‐Caris, Milou Dingemans, Astrid Reus, Sanah Majid Shaikh, Julian Muñoz Sierra, Ursula Karges, Tim aus der Beek, Eugénia Nogueiro, Christopher Lythgo, Juan Manuel Parra Morte, Maria Bastaki, Rositsa Serafimova, Anja Friel, Daniele Court Marques, Andreas Uphoff, Lucie Bielska, Claudio Putzu, Laura Ruggeri, Paschalina Papadaki

Publikováno v: EFSA Journal, Vol 21, Iss 8, Pp n/a-n/a (2023)

Abstract This guidance document provides a tiered framework for risk assessors and facilitates risk managers in making decisions concerning the approval of active substances (AS) that are chemicals in plant protection products (PPPs) and biocidal pro

Externí odkaz: https://doaj.org/article/738cdbc6c29a429badc1019877f4afac

Application of AOPs to assist regulatory assessment of chemical risks – Case studies, needs and recommendations

Autor: Lola Bajard, Ondrej Adamovsky, Karine Audouze, Kirsten Baken, Robert Barouki, Joost B. Beltman, Anna Beronius, Eva Cecilie Bonefeld-Jørgensen, German Cano-Sancho, Milo L. de Baat, Filippo Di Tillio, Mariana F. Fernández, Rex E. FitzGerald, Claudia Gundacker, Antonio F. Hernández, Klara Hilscherova, Spyros Karakitsios, Eliska Kuchovska, Manhai Long, Mirjam Luijten, Sanah Majid, Philip Marx-Stoelting, Vicente Mustieles, Chander K. Negi, Dimosthenis Sarigiannis, Stefan Scholz, Iva Sovadinova, Rob Stierum, Shihori Tanabe, Knut Erik Tollefsen, Annick D. van den Brand, Carolina Vogs, Maria Wielsøe, Clemens Wittwehr, Ludek Blaha

Publikováno v: Environmental Research
Environmental Research. Elsevier BV
Bajard, L, Adamovsky, O, Audouze, K, Baken, K, Barouki, R, Beltman, J B, Beronius, A, Bonefeld-Jørgensen, E C, Cano-Sancho, G, de Baat, M L, Di Tillio, F, Fernández, M F, FitzGerald, R E, Gundacker, C, Hernández, A F, Hilscherova, K, Karakitsios, S, Kuchovska, E, Long, M, Luijten, M, Majid, S, Marx-Stoelting, P, Mustieles, V, Negi, C K, Sarigiannis, D, Scholtz, S, Sovadinova, I, Stierum, R, Tanabe, S, Tollefsen, K E, van den Brand, A D, Vogs, C, Wielsøe, M, Wittwehr, C & Blaha, L 2023, ' Application of AOPs to assist regulatory assessment of chemical risks-Case studies, needs and recommendations ', Environmental Research, vol. 217, 114650 . https://doi.org/10.1016/j.envres.2022.114650

While human regulatory risk assessment (RA) still largely relies on animal studies, new approach methodologies (NAMs) based on in vitro, in silico or non-mammalian alternative models are increasingly used to evaluate chemical hazards. Moreover, human

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1237a39508f13a4f75cb37a29540292