Synthesis of the Novel N -(2-Hexadecynoyl)-l-Homoserine Lactone and Evaluation of Its Antiquorum Sensing Activity in Chromobacterium violaceum .

Autor: Sanabria-Ríos DJ; Faculty of Science and Technology, Inter American University of Puerto Rico, Metropolitan Campus, P.O. Box 191293, San Juan, Puerto Rico 00919, United States.; Medicinal Research and Applications Laboratory, Inter American University of Puerto Rico, Metropolitan Campus, P.O. Box 191293, San Juan, Puerto Rico 00919, United States., García-Del-Valle R; Department of Chemistry, University of Puerto Rico, Río Piedras Campus, 17 Ave Universidad STE 1701, San Juan, Puerto Rico 00925, United States., Bosh-Fonseca S; Faculty of Science and Technology, Inter American University of Puerto Rico, Metropolitan Campus, P.O. Box 191293, San Juan, Puerto Rico 00919, United States., González-Pagán J; Faculty of Science and Technology, Inter American University of Puerto Rico, Metropolitan Campus, P.O. Box 191293, San Juan, Puerto Rico 00919, United States., Díaz-Rosa A; Faculty of Science and Technology, Inter American University of Puerto Rico, Metropolitan Campus, P.O. Box 191293, San Juan, Puerto Rico 00919, United States., Acevedo-Rosario K; Faculty of Science and Technology, Inter American University of Puerto Rico, Metropolitan Campus, P.O. Box 191293, San Juan, Puerto Rico 00919, United States., Reyes-Vicente L; Faculty of Science and Technology, Inter American University of Puerto Rico, Metropolitan Campus, P.O. Box 191293, San Juan, Puerto Rico 00919, United States.; Medicinal Research and Applications Laboratory, Inter American University of Puerto Rico, Metropolitan Campus, P.O. Box 191293, San Juan, Puerto Rico 00919, United States., Colom A; Faculty of Science and Technology, Inter American University of Puerto Rico, Metropolitan Campus, P.O. Box 191293, San Juan, Puerto Rico 00919, United States., Carballeira NM; Department of Chemistry, University of Puerto Rico, Río Piedras Campus, 17 Ave Universidad STE 1701, San Juan, Puerto Rico 00925, United States.

Publikováno v: ACS omega [ACS Omega] 2024 Jul 22; Vol. 9 (30), pp. 32536-32546. Date of Electronic Publication: 2024 Jul 22 (Print Publication: 2024).

Antibacterial Activity of Hexadecynoic Acid Isomers toward Clinical Isolates of Multidrug-Resistant Staphylococcus aureus.

Autor: Sanabria-Ríos DJ; Faculty of Science and Technology, Inter American University of Puerto Rico, Metropolitan Campus, PO Box 191293, San Juan, PR, 00919, USA., Morales-Guzmán C; Department of Chemistry, University of Puerto Rico, Río Piedras Campus, 17 Ave Universidad STE 1701, San Juan, PR, 00925, USA., Mooney J; Faculty of Science and Technology, Inter American University of Puerto Rico, Metropolitan Campus, PO Box 191293, San Juan, PR, 00919, USA., Medina S; Faculty of Science and Technology, Inter American University of Puerto Rico, Metropolitan Campus, PO Box 191293, San Juan, PR, 00919, USA., Pereles-De-León T; Faculty of Science and Technology, Inter American University of Puerto Rico, Metropolitan Campus, PO Box 191293, San Juan, PR, 00919, USA., Rivera-Román A; Faculty of Science and Technology, Inter American University of Puerto Rico, Metropolitan Campus, PO Box 191293, San Juan, PR, 00919, USA., Ocasio-Malavé C; Faculty of Science and Technology, Inter American University of Puerto Rico, Metropolitan Campus, PO Box 191293, San Juan, PR, 00919, USA., Díaz D; Faculty of Science and Technology, Inter American University of Puerto Rico, Metropolitan Campus, PO Box 191293, San Juan, PR, 00919, USA., Chorna N; Department of Biochemistry, University of Puerto Rico, Medical Sciences, Campus, PO Box 365067, San Juan, PR, 00936, USA., Carballeira NM; Department of Chemistry, University of Puerto Rico, Río Piedras Campus, 17 Ave Universidad STE 1701, San Juan, PR, 00925, USA.

Publikováno v: Lipids [Lipids] 2020 Mar; Vol. 55 (2), pp. 101-116. Date of Electronic Publication: 2020 Jan 24.

Conjugation inhibitors compete with palmitic acid for binding to the conjugative traffic ATPase TrwD, providing a mechanism to inhibit bacterial conjugation.

Autor: García-Cazorla Y; From the Departamento de Biología Molecular and Instituto de Biomedicina y Biotecnología de Cantabria, Universidad de Cantabria-Consejo Superior de Investigaciones Científicas, 39011 Santander, Spain., Getino M; From the Departamento de Biología Molecular and Instituto de Biomedicina y Biotecnología de Cantabria, Universidad de Cantabria-Consejo Superior de Investigaciones Científicas, 39011 Santander, Spain., Sanabria-Ríos DJ; the Inter-American University of Puerto Rico, Metropolitan Campus, Faculty of Science and Technology, San Juan, Puerto Rico 00919, and., Carballeira NM; the Department of Chemistry, University of Puerto Rico, Rio Piedras Campus, San Juan, Puerto Rico 00925., de la Cruz F; From the Departamento de Biología Molecular and Instituto de Biomedicina y Biotecnología de Cantabria, Universidad de Cantabria-Consejo Superior de Investigaciones Científicas, 39011 Santander, Spain., Arechaga I; From the Departamento de Biología Molecular and Instituto de Biomedicina y Biotecnología de Cantabria, Universidad de Cantabria-Consejo Superior de Investigaciones Científicas, 39011 Santander, Spain, arechagai@unican.es., Cabezón E; From the Departamento de Biología Molecular and Instituto de Biomedicina y Biotecnología de Cantabria, Universidad de Cantabria-Consejo Superior de Investigaciones Científicas, 39011 Santander, Spain, cabezone@unican.es.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2018 Oct 26; Vol. 293 (43), pp. 16923-16930. Date of Electronic Publication: 2018 Sep 10.

The (5Z)-5-Pentacosenoic and 5-Pentacosynoic Acids Inhibit the HIV-1 Reverse Transcriptase.

Autor: Moreira LG; Department of Chemistry, University of Puerto Rico, Rio Piedras Campus, PO Box 23346, San Juan, PR, 00931-3346, USA., Orellano EA; Department of Chemistry, University of Puerto Rico, Rio Piedras Campus, PO Box 23346, San Juan, PR, 00931-3346, USA., Rosado K; Department of Chemistry, University of Puerto Rico, Rio Piedras Campus, PO Box 23346, San Juan, PR, 00931-3346, USA., Guido RV; Laboratório de Química Medicinal e Computacional, Centro de Pesquisa e Inovação em Biodiversidade e Fármacos, Instituto de Física de São Carlos, Universidade de São Paulo, Avenida João Dagnone 1100, Jardim Santa Angelina, São Carlos, SP, 13563-120, Brazil., Andricopulo AD; Laboratório de Química Medicinal e Computacional, Centro de Pesquisa e Inovação em Biodiversidade e Fármacos, Instituto de Física de São Carlos, Universidade de São Paulo, Avenida João Dagnone 1100, Jardim Santa Angelina, São Carlos, SP, 13563-120, Brazil., Soto GO; Department of Microbiology and Immunology, Universidad Central del Caribe School of Medicine, PO Box 60327, Bayamón, PR, 00960, USA., Rodríguez JW; Department of Microbiology and Immunology, Universidad Central del Caribe School of Medicine, PO Box 60327, Bayamón, PR, 00960, USA., Sanabria-Ríos DJ; Faculty of Science and Technology, Inter American University of Puerto Rico, Metropolitan Campus, PO Box 191293, San Juan, PR, 00919, USA., Carballeira NM; Department of Chemistry, University of Puerto Rico, Rio Piedras Campus, PO Box 23346, San Juan, PR, 00931-3346, USA. nestor.carballeira1@upr.edu.

Publikováno v: Lipids [Lipids] 2015 Oct; Vol. 50 (10), pp. 1043-50. Date of Electronic Publication: 2015 Sep 07.

Synthesis of novel C5-curcuminoid-fatty acid conjugates and mechanistic investigation of their anticancer activity.

Autor: Sanabria-Ríos DJ; Faculty of Science and Technology, Inter American University of Puerto Rico, Metropolitan Campus, PO Box 191293, San Juan, PR 00919, United States. Electronic address: dsanabria@intermetro.edu., Rivera-Torres Y; Faculty of Science and Technology, Inter American University of Puerto Rico, Metropolitan Campus, PO Box 191293, San Juan, PR 00919, United States., Rosario J; Faculty of Science and Technology, Inter American University of Puerto Rico, Metropolitan Campus, PO Box 191293, San Juan, PR 00919, United States., Ríos C; Faculty of Science and Technology, Inter American University of Puerto Rico, Metropolitan Campus, PO Box 191293, San Juan, PR 00919, United States., Gutierrez R; Faculty of Science and Technology, Inter American University of Puerto Rico, Metropolitan Campus, PO Box 191293, San Juan, PR 00919, United States., Carballeira NM; Department of Chemistry, University of Puerto Rico, Rio Piedras Campus, PO Box 23346, San Juan, PR 00931-3346, United States., Vélez C; School of Environmental Affairs, Universidad Metropolitana, PO Box 21150, San Juan, PR 00928, United States., Zayas B; School of Environmental Affairs, Universidad Metropolitana, PO Box 21150, San Juan, PR 00928, United States., Álvarez-Colón F; Department of Microbiology and Immunology, Universidad Central del Caribe School of Medicine, PO Box 60327, Bayamón, PR 00960, United States., Ortiz-Soto G; Department of Microbiology and Immunology, Universidad Central del Caribe School of Medicine, PO Box 60327, Bayamón, PR 00960, United States., Serrano V; Department of Microbiology and Immunology, Universidad Central del Caribe School of Medicine, PO Box 60327, Bayamón, PR 00960, United States., Altieri-Rivera J; Department of Microbiology and Immunology, Universidad Central del Caribe School of Medicine, PO Box 60327, Bayamón, PR 00960, United States., Ríos-Olivares E; Department of Microbiology and Immunology, Universidad Central del Caribe School of Medicine, PO Box 60327, Bayamón, PR 00960, United States., Rodríguez JW; Department of Microbiology and Immunology, Universidad Central del Caribe School of Medicine, PO Box 60327, Bayamón, PR 00960, United States.

Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2015; Vol. 25 (10), pp. 2174-80. Date of Electronic Publication: 2015 Mar 31.