Estradiol reduction through aromatase inhibition impairs cocaine seeking in male rats

Autor: John K. Alvarado-Torres, Roberto Morales-Silva, Alexia Sanabria Ponce de Leon, Genesis Rodriguez-Torres, Joshua Perez-Torres, Yobet Perez-Perez, Devin Mueller, Marian T. Sepulveda-Orengo

Publikováno v: Frontiers in Behavioral Neuroscience, Vol 17 (2024)

IntroductionClinical and preclinical research on cocaine use disorder (CUD) has shown that sex differences in drug seeking are influenced by hormonal fluctuations. Estradiol (E2), a sex steroid hormone, has been linked to female drug effects, vulnera

Externí odkaz: https://doaj.org/article/91b26fd6f4084f0dae9ceecf21ff5e39

Estradiol reduction through aromatase inhibition impairs cocaine seeking in male rats.

Autor: Alvarado-Torres JK; Basic Sciences Department, Ponce Research Institute, Ponce Health Sciences University, Ponce, Puerto Rico., Morales-Silva R; Basic Sciences Department, Ponce Research Institute, Ponce Health Sciences University, Ponce, Puerto Rico., Sanabria Ponce de Leon A; Department of Biomedical Sciences, Pontifical Catholic University of Puerto Rico, Ponce, Puerto Rico., Rodriguez-Torres G; Basic Sciences Department, Ponce Research Institute, Ponce Health Sciences University, Ponce, Puerto Rico., Perez-Torres J; Basic Sciences Department, Ponce Research Institute, Ponce Health Sciences University, Ponce, Puerto Rico., Perez-Perez Y; Basic Sciences Department, Ponce Research Institute, Ponce Health Sciences University, Ponce, Puerto Rico., Mueller D; Department of Biological Sciences, Kent State University, Kent, OH, United States., Sepulveda-Orengo MT; Basic Sciences Department, Ponce Research Institute, Ponce Health Sciences University, Ponce, Puerto Rico.

Publikováno v: Frontiers in behavioral neuroscience [Front Behav Neurosci] 2024 Jan 16; Vol. 17, pp. 1307606. Date of Electronic Publication: 2024 Jan 16 (Print Publication: 2023).