Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Sanaa Tahiri"'
Autor:
W. Michael Korn, Sanaa Tahiri, Regina Linetskaya, Ryan Courtin, Sharvina Ziyeh, Anna Ong, Elizabeth Dito, Alan P. Venook, R. Kate Kelley, Eric A. Collisson, Margaret A. Tempero, Peter Kuhn, AmirAli Talasaz, Nancy M. Joseph, Olga M. Mirzoeva, Jessica Van Ziffle, Tanios Bekaii-Saab, Andrew H. Ko
Purpose: On the basis of preclinical evidence of synergistic activity between MEK and EGFR inhibitors in pancreatic ductal adenocarcinoma (PDAC), we evaluated the safety and efficacy of selumetinib, a MEK1/2 inhibitor, plus erlotinib in patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c150d61e444e1d4c5806c0617b36149
https://doi.org/10.1158/1078-0432.c.6524340.v1
https://doi.org/10.1158/1078-0432.c.6524340.v1
Autor:
W. Michael Korn, Sanaa Tahiri, Regina Linetskaya, Ryan Courtin, Sharvina Ziyeh, Anna Ong, Elizabeth Dito, Alan P. Venook, R. Kate Kelley, Eric A. Collisson, Margaret A. Tempero, Peter Kuhn, AmirAli Talasaz, Nancy M. Joseph, Olga M. Mirzoeva, Jessica Van Ziffle, Tanios Bekaii-Saab, Andrew H. Ko
Supplemental figure 3. Mutation frequencies in pre-and on-treatment plasma samples as determined by next-generation sequencing of cfDNA using the Guardant360 assay.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4d178c527541c3780f64e59a214d8d0
https://doi.org/10.1158/1078-0432.22459914.v1
https://doi.org/10.1158/1078-0432.22459914.v1
Autor:
Gregory B. Lesinski, Tanios Bekaii-Saab, Miguel Villalona-Calero, Anne M. Noonan, Daniel Ahn, Sanaa Tahiri, Kristen Ciombor, Christina Wu, Sameh Mikhail, Susan Geyer, Thomas A. Mace, Matthew R. Farren
supplemental legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::541ea24e0e66538aa04451521f16f756
https://doi.org/10.1158/1078-0432.22458234
https://doi.org/10.1158/1078-0432.22458234
Autor:
Gregory B. Lesinski, Tanios Bekaii-Saab, Miguel Villalona-Calero, Anne M. Noonan, Daniel Ahn, Sanaa Tahiri, Kristen Ciombor, Christina Wu, Sameh Mikhail, Susan Geyer, Thomas A. Mace, Matthew R. Farren
Purpose: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with a 5-year survival rate Experimental Design: Peripheral blood was collected from 73 patients presenting with previously untreated metastatic PDAC. Extensive immunologic prof
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d4bc9804b0eab79b0267b82851a905c
https://doi.org/10.1158/1078-0432.c.6523881
https://doi.org/10.1158/1078-0432.c.6523881
Autor:
Gregory B. Lesinski, Tanios Bekaii-Saab, Miguel Villalona-Calero, Anne M. Noonan, Daniel Ahn, Sanaa Tahiri, Kristen Ciombor, Christina Wu, Sameh Mikhail, Susan Geyer, Thomas A. Mace, Matthew R. Farren
Table S1. Antibodies used for flow cytometry Table S2. Monte Carlo cross-validation of continuous measure markers. Table S3. Monte Carlo cross-validation of dichotomous measure markers. Table S4. Pancreatic cancer patient circulating immune cell freq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04f56ce42cf207d1d863bbd554765992
https://doi.org/10.1158/1078-0432.22458237.v1
https://doi.org/10.1158/1078-0432.22458237.v1
Autor:
W. Michael Korn, Sanaa Tahiri, Regina Linetskaya, Ryan Courtin, Sharvina Ziyeh, Anna Ong, Elizabeth Dito, Alan P. Venook, R. Kate Kelley, Eric A. Collisson, Margaret A. Tempero, Peter Kuhn, AmirAli Talasaz, Nancy M. Joseph, Olga M. Mirzoeva, Jessica Van Ziffle, Tanios Bekaii-Saab, Andrew H. Ko
Supplemental figure 1. Abdominal CT scans from a patient who achieved minor response following 2 cycles of treatment. Representative sections from baseline (left) and on-treatment (right) scans are shown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f36492a194cf605b505dc14b2c73725
https://doi.org/10.1158/1078-0432.22459920.v1
https://doi.org/10.1158/1078-0432.22459920.v1
Autor:
W. Michael Korn, Sanaa Tahiri, Regina Linetskaya, Ryan Courtin, Sharvina Ziyeh, Anna Ong, Elizabeth Dito, Alan P. Venook, R. Kate Kelley, Eric A. Collisson, Margaret A. Tempero, Peter Kuhn, AmirAli Talasaz, Nancy M. Joseph, Olga M. Mirzoeva, Jessica Van Ziffle, Tanios Bekaii-Saab, Andrew H. Ko
Supplemental figure 2. Distribution of proportion of E-cadherin expressing tumor cells across all cases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f941dd6998462a78f3a157d69c60ce1
https://doi.org/10.1158/1078-0432.22459917
https://doi.org/10.1158/1078-0432.22459917
Autor:
Sanaa Tahiri, Amir Ali Talasaz, Elizabeth Dito, R. Kate Kelley, Anna Ong, W. Michael Korn, Andrew H. Ko, Ryan Courtin, Eric A. Collisson, Tanios Bekaii-Saab, Nancy M. Joseph, Regina Linetskaya, Jessica Van Ziffle, Olga M. Mirzoeva, Margaret A. Tempero, Peter Kuhn, Alan P. Venook, Sharvina Ziyeh
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research, vol 22, iss 1
Purpose: On the basis of preclinical evidence of synergistic activity between MEK and EGFR inhibitors in pancreatic ductal adenocarcinoma (PDAC), we evaluated the safety and efficacy of selumetinib, a MEK1/2 inhibitor, plus erlotinib in patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fdb6a0a11a33489f81fa6895fc40168
https://doi.org/10.1158/1078-0432.ccr-15-0979
https://doi.org/10.1158/1078-0432.ccr-15-0979
Autor:
Marlo Blazer, Sameh Mikhail, Samer El-Dika, Michael V. Knopp, D J Clark, Lai Wei, Jon P. Walker, J Liu, Jonathan Rock, Xiangyu Yang, Cynthia Timmers, Christina Wu, James L. Chen, Alison Neal, T. Bekaii-Saab, Sanaa Tahiri
Publikováno v:
British Journal of Cancer
Background: Blockade of the vascular endothelial growth factor (VEGF) pathway shows evidence of activity in gastro-oesophageal (GE) and oesophageal cancer. We investigated the efficacy of sunitinib, a multikinase VEGF inhibitor, in patients with rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ad724317b2876702236ef06975d170a
http://europepmc.org/articles/PMC4506385
http://europepmc.org/articles/PMC4506385
Autor:
Thomas Olencki, Gregory B. Lesinski, Sanaa Tahiri, Kari Kendra, Amir Mortazavi, Thomas A. Mace, Susan Geyer, William E. Carson, Arvinder Bhinder, Steven K. Clinton, Elaine T. Lam, Paul Monk
Publikováno v:
Journal of Immunotherapy (Hagerstown, Md. : 1997)
This study was designed to evaluate the safety and feasibility of high-dose interleukin-2 (HD IL-2) followed by sorafenib in patients with metastatic melanoma (MM) and renal cell carcinoma (RCC). Biomarkers relevant to the antitumor effects of IL-2 t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cb300e66e2c671b0c53e2d61cd5cf0f
http://europepmc.org/articles/PMC3966917
http://europepmc.org/articles/PMC3966917