Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Sana, Hibino"'
Autor:
Masahiro Okada, Shunsuke Chikuma, Taisuke Kondo, Sana Hibino, Hiroaki Machiyama, Tadashi Yokosuka, Miyako Nakano, Akihiko Yoshimura
Publikováno v:
Cell Reports, Vol 20, Iss 5, Pp 1017-1028 (2017)
Summary: Programmed cell death 1 (PD-1) is highly expressed on exhausted T cells and inhibits T cell activation. Antibodies that block the interaction between PD-1 and its ligand prevent this inhibitory signal and reverse T cell dysfunction, providin
Externí odkaz:
https://doaj.org/article/447b1be0ffb445a390e9d533575a28d9
Autor:
Akihiko Yoshimura, Setsuko Omata-Mise, Hiroko Nakatsukasa, Minako Ito, Taisuke Kondo, Shunsuke Chikuma, Sana Hibino
Supplementary methods and legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1afb47aa67335ceb1d18c457cd0d9fc3
https://doi.org/10.1158/0008-5472.22420338
https://doi.org/10.1158/0008-5472.22420338
Autor:
Akihiko Yoshimura, Setsuko Omata-Mise, Hiroko Nakatsukasa, Minako Ito, Taisuke Kondo, Shunsuke Chikuma, Sana Hibino
Camptothecin and a COX-2 inhibitor regulate Treg-mediated down-regulation of costimulatory molecules on tumor-infiltrating DCs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81f5efce35c211cefd9e268a318aaec3
https://doi.org/10.1158/0008-5472.22420341
https://doi.org/10.1158/0008-5472.22420341
Autor:
Akihiko Yoshimura, Setsuko Omata-Mise, Hiroko Nakatsukasa, Minako Ito, Taisuke Kondo, Shunsuke Chikuma, Sana Hibino
Enhanced infiltration of regulatory T cells (Treg) into tumor tissue is detrimental to patients with cancer and is closely associated with poor prognosis as they create an immunosuppressive state that suppresses antitumor immune responses. Therefore,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8491f41138b5e29f6bdc3c47d6b8318b
https://doi.org/10.1158/0008-5472.c.6510627
https://doi.org/10.1158/0008-5472.c.6510627
Autor:
Takashi Sekiya, Sana Hibino, Keita Saeki, Mitsuhiro Kanamori, Satoshi Takaki, Akihiko Yoshimura
Publikováno v:
Cell Reports, Vol 24, Iss 6, Pp 1627-1638.e6 (2018)
Summary: Regulatory T (Treg) cells develop from a self-reactive, CD4-single positive (CD4SP) precursor cell pool. Thus, Treg-fated developing thymocytes are expected to possess the potential to generate pathogenic self-reactive cells. However, no suc
Externí odkaz:
https://doaj.org/article/66a305dfc10540d8a353519d34058c55
Autor:
Hideyuki Yanai, Daisuke Yamamoto, Kazuhiko Koike, Ching-Yun Chang, Tatsuhiko Kodama, Sho Hangai, Masanobu Oshima, Sana Hibino, Takeshi Kawamura, Hiroko Oshima, Yousuke Nakai, Ryosuke Tateishi, Tadatsugu Taniguchi, Kyoji Moriya, Yoshitaka Kimura
Publikováno v:
Nature Immunology. 22:947-957
One of most challenging issues in tumor immunology is a better understanding of the dynamics in the accumulation of myeloid-derived suppressor cells (MDSCs) in the tumor microenvironment (TIME), as this would lead to the development of new cancer the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7543c14999072755a25b49254891dae7
https://doi.org/10.1038/s41590-021-00967-5
https://doi.org/10.1038/s41590-021-00967-5
Autor:
Sana Hibino, Shotaro Eto, Sho Hangai, Keiko Endo, Sanae Ashitani, Maki Sugaya, Tsuyoshi Osawa, Tomoyoshi Soga, Tadatsugu Taniguchi, Hideyuki Yanai
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 6/13/2023, Vol. 120 Issue 24, p1-10, 31p
Autor:
Shinji Itoh, Hidenori Kasahara, Takatsugu Ishimoto, Koji Taniguchi, Tetsuro Kawazoe, Sana Hibino, Mamiko Sakata-Yanagimoto
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 5421, p 5421 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 5421, p 5421 (2021)
Inflammation, especially chronic inflammation, plays a pivotal role in tumorigenesis and metastasis through various mechanisms and is now recognized as a hallmark of cancer and an attractive therapeutic target in cancer. In this review, we discuss re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6314addbf1c7ae08707e3356522d8f2e
http://europepmc.org/articles/PMC8196678
http://europepmc.org/articles/PMC8196678
Autor:
Naoyuki, Senda, Hideyuki, Yanai, Sana, Hibino, Lei, Li, Yu, Mizushima, Tomomitsu, Miyagaki, Mai, Saeki, Yusuke, Kishi, Sho, Hangai, Junko, Nishio, Makoto, Sugaya, Tadatsugu, Taniguchi, Shinichi, Sato
Publikováno v:
Proc Natl Acad Sci U S A
Dysregulation of inflammatory cytokines in keratinocytes promote the pathogenesis of the skin inflammation, such as allergic contact dermatitis (ACD). High-mobility group box 1 protein (HMGB1) has been implicated in the promotion of skin inflammation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::09d64f67d940704f296cb243036edc5f
https://pubmed.ncbi.nlm.nih.gov/33443188
https://pubmed.ncbi.nlm.nih.gov/33443188
Autor:
Yu Mizushima, Lei Li, Tadatsugu Taniguchi, Sana Hibino, Yusuke Kishi, Hideyuki Yanai, Shinichi Sato, Mai Saeki, Tomomitsu Miyagaki, Makoto Sugaya, Junko Nishio, Naoyuki Senda, Sho Hangai
Publikováno v:
Proceedings of the National Academy of Sciences. 118
Dysregulation of inflammatory cytokines in keratinocytes promote the pathogenesis of the skin inflammation, such as allergic contact dermatitis (ACD). High-mobility group box 1 protein (HMGB1) has been implicated in the promotion of skin inflammation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fecde0a876ad35c5734c7e2679f5d294
https://doi.org/10.1073/pnas.2022343118
https://doi.org/10.1073/pnas.2022343118