Zobrazeno 1 - 10
of 68
pro vyhledávání: '"San Yee"'
Publikováno v:
Heliyon, Vol 10, Iss 21, Pp e39677- (2024)
Oral squamous cell carcinoma (OSCC) is known to be driven by multiple intricated receptor tyrosine kinases (RTKs) including EGFR, PI3K/AKT and MAPK signaling pathways. However, whilst targeting EGFR with cetuximab has been approved for the treatment
Externí odkaz:
https://doaj.org/article/4d3833f21f594f75aed68e2603d4966a
Autor:
ASLAM, MOHAMED1 maslam@um.edu.my, LIEW SAN YEE2 sanyee26@gmail.com
Publikováno v:
Journal of Management & Training for Industries. 2023, Vol. 10 Issue 2, p37-58. 22p.
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Immunotherapy, especially the immune checkpoint inhibitors (ICIs) such as the pembrolizumab and nivolumab have contributed to significant improvements in treatment outcomes and survival of head and neck cancer (HNC) patients. Still, only a subset of
Externí odkaz:
https://doaj.org/article/9d2e7d54699141b896fc79923afb06eb
Autor:
Nur Syafinaz Zainal, Bernard Kok Bang Lee, Zheng Wei Wong, Iuan Sheau Chin, Pei San Yee, Chai Phei Gan, Kein Seong Mun, Zainal Ariff Abdul Rahman, J. Silvio Gutkind, Vyomesh Patel, Sok Ching Cheong
Publikováno v:
Cancer Biology & Medicine, Vol 16, Iss 2, Pp 264-275 (2019)
Objective Lack of effective therapies remains a problem in the treatment of oral squamous cell carcinoma (OSCC), especially in patients with advanced tumors. OSCC development is driven by multiple aberrancies within the cell cycle pathway, including
Externí odkaz:
https://doaj.org/article/0cbed0837b6a4998adfdc5845bbf03bb
Autor:
Kai Hung Tiong, Jit Kang Chang, Dharini Pathmanathan, Muhammad Zaki Hidayatullah Fadlullah, Pei San Yee, Chee Sun Liew, Zainal Ariff Abdul Rahman, Kheng Ling Beh, Sok Ching Cheong
Publikováno v:
BioTechniques, Vol 65, Iss 6, Pp 322-330 (2018)
We describe a novel automated cell detection and counting software, QuickCount® (QC), designed for rapid quantification of cells. The Bland–Altman plot and intraclass correlation coefficient (ICC) analyses demonstrated strong agreement between cel
Externí odkaz:
https://doaj.org/article/40e512ec0d2d4d248c906a19fdb7b561
Genome-wide CRISPR screens of oral squamous cell carcinoma reveal fitness genes in the Hippo pathway
Autor:
Annie Wai Yeeng Chai, Pei San Yee, Stacey Price, Shi Mun Yee, Hui Mei Lee, Vivian KH Tiong, Emanuel Gonçalves, Fiona M Behan, Jessica Bateson, James Gilbert, Aik Choon Tan, Ultan McDermott, Mathew J Garnett, Sok Ching Cheong
Publikováno v:
eLife, Vol 9 (2020)
New therapeutic targets for oral squamous cell carcinoma (OSCC) are urgently needed. We conducted genome-wide CRISPR-Cas9 screens in 21 OSCC cell lines, primarily derived from Asians, to identify genetic vulnerabilities that can be explored as therap
Externí odkaz:
https://doaj.org/article/3808165fca334dd0b13ce47927c27467
Publikováno v:
Open Journal of Geology. 12:1102-1119
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3eeffa8e432f69737a0165e3d0bdd407
https://doi.org/10.4236/ojg.2022.1212052
https://doi.org/10.4236/ojg.2022.1212052
Autor:
Pei San Yee, Annie Wai Yeeng Chai, Shi Mun Yee, Shi Yin Ooi, Yee Hua Tan, Mathew Garnett, Siew Kit Ng, Sok Ching Cheong
Publikováno v:
Cancer Research. 83:1704-1704
Treating oral squamous cell carcinoma (OSCC) remains challenging due to limited knowledge of the critical genes that could affect cell survival in OSCC. We have previously utilized genome-wide CRISPR-Cas9 knockout functional screens to explore the ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0156e6c8b4159d0d5ff18378eb6079cf
https://doi.org/10.1158/1538-7445.am2023-1704
https://doi.org/10.1158/1538-7445.am2023-1704
Publikováno v:
Frontiers in oncology. 12
Immunotherapy, especially the immune checkpoint inhibitors (ICIs) such as the pembrolizumab and nivolumab have contributed to significant improvements in treatment outcomes and survival of head and neck cancer (HNC) patients. Still, only a subset of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cbfad049e290d64b5c738f6c6b3f20b
https://pubmed.ncbi.nlm.nih.gov/35372020
https://pubmed.ncbi.nlm.nih.gov/35372020
Autor:
Khaing, San Yee1 (AUTHOR), Sugai, Yuichi2 (AUTHOR) sugai@mine.kyushu-u.ac.jp, Sasaki, Kyuro2 (AUTHOR)
Publikováno v:
Scientific Reports. 3/12/2019, Vol. 9 Issue 1, p1-10. 10p.