Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Samy Sakkal"'
Autor:
Rhian Stavely, Ainsley M. Robinson, Sarah Fraser, Rhiannon T. Filippone, Vanesa Stojanovska, Rajaraman Eri, Vasso Apostolopoulos, Samy Sakkal, Kulmira Nurgali
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Current treatments for inflammatory bowel disease (IBD) are often inadequate due to limited efficacy and toxicity, leading to surgical resection in refractory cases. IBD’s broad and complex pathogenesis involving the immune system, enteric
Externí odkaz:
https://doaj.org/article/54b591fab2994f8291ce6a82ddc071cf
Autor:
Erik D. Hanson, Samy Sakkal, Lauren C. Bates-Fraser, Shadney Que, Eunhan Cho, Guillaume Spielmann, Elif Kadife, John A. Violet, Claudio L. Battaglini, Lee Stoner, David B. Bartlett, Glenn K. McConell, Alan Hayes
Publikováno v:
Frontiers in Sports and Active Living, Vol 5 (2023)
BackgroundReduced testosterone levels can influence immune system function, particularly T cells. Exercise during cancer reduces treatment-related side effects and provide a stimulus to mobilize and redistribute immune cells. However, it is unclear h
Externí odkaz:
https://doaj.org/article/e542ae7e8af74c2e8b552d2d8fe126f9
Publikováno v:
Biomolecules, Vol 13, Iss 11, p 1586 (2023)
Oxidative stress is increasingly recognized as a central player in a range of gastrointestinal (GI) disorders, as well as complications stemming from therapeutic interventions. This article presents an overview of the mechanisms of oxidative stress i
Externí odkaz:
https://doaj.org/article/0a2307c5bc53443e86b16efc61c4ce6e
Publikováno v:
Nutrients, Vol 15, Iss 11, p 2562 (2023)
The shift in modern dietary regimens to “Western style” and sedentary lifestyles are believed to be partly responsible for the increase in the global burden of cardiovascular diseases. Natural products have been used throughout human history as t
Externí odkaz:
https://doaj.org/article/7412feccfdfb48848d19eb8e9c5fc17e
Autor:
Rhian Stavely, Lauren Sahakian, Rhiannon T. Filippone, Vanesa Stojanovska, Joel C. Bornstein, Samy Sakkal, Kulmira Nurgali
Publikováno v:
Biomolecules, Vol 12, Iss 12, p 1831 (2022)
High-mobility group box 1 (HMGB1) is a damage-associated molecular pattern released by dying cells to stimulate the immune response. During cell death, HMGB1 is translocated from the nucleus to the cytoplasm and passively released. High levels of sec
Externí odkaz:
https://doaj.org/article/70cf50452d6f465686deeaf42b08e7f2
Autor:
Ainsley M. Robinson, Ahmed A. Rahman, Sarah Miller, Rhian Stavely, Samy Sakkal, Kulmira Nurgali
Publikováno v:
Stem Cell Research & Therapy, Vol 8, Iss 1, Pp 1-18 (2017)
Abstract Background The incidence of inflammatory bowel diseases (IBD) is increasing worldwide with patients experiencing severe impacts on their quality of life. It is well accepted that intestinal inflammation associates with extensive damage to th
Externí odkaz:
https://doaj.org/article/f2b83f468fb240d1a88769c9492e8184
Autor:
Vanesa Stojanovska, Rachel M McQuade, Sarah Fraser, Monica Prakash, Shakuntla Gondalia, Rhian Stavely, Enzo Palombo, Vasso Apostolopoulos, Samy Sakkal, Kulmira Nurgali
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0198359 (2018)
Oxaliplatin is a platinum-based chemotherapeutic used for cancer treatment. Its use associates with peripheral neuropathies and chronic gastrointestinal side-effects. Oxaliplatin induces immunogenic cell death by provoking the presentation of damage
Externí odkaz:
https://doaj.org/article/3e0a45eb421144e59c72d9d01bd85bb6
Autor:
Erik D. Hanson, Claudio L. Battaglini, John Violet, Samy Sakkal, Guillaume Spielmann, Lee Stoner, Elif Kadife, Eunhan Cho, Glenn K. McConell, Alan Hayes, David B. Bartlett, Shadney Que
Publikováno v:
Experimental Physiology. 105:1524-1539
NEW FINDINGS What is the central question of this study? What are the characteristics of the NK cell response following acute moderate-intensity aerobic exercise in prostate cancer survivors and is there a relationship between stress hormones and NK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d44363b3a9830d5ff159752b3f73944
https://doi.org/10.1113/ep088627
https://doi.org/10.1113/ep088627
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0139023 (2015)
BACKGROUND & AIMS:The therapeutic benefits of mesenchymal stem cells (MSCs), such as homing ability, multipotent differentiation capacity and secretion of soluble bioactive factors which exert neuroprotective, anti-inflammatory and immunomodulatory p
Externí odkaz:
https://doaj.org/article/1bd9628a61a6402eac85e2c8a7209704
Publikováno v:
Maturitas. 117:34-44
Platelet-rich plasma is an autologous and safe blood product containing a high concentration of platelets and leucocytes. Platelets, growth factors, leucocytes and plasma are fundamental fibroblast proliferation agents. Leucocytes' plasticity, repara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14e66708075d26e09537e7c06cd9e739
https://doi.org/10.1016/j.maturitas.2018.09.001
https://doi.org/10.1016/j.maturitas.2018.09.001