Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Samy Hakroush"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionRapidly progressive glomerulonephritis (RPGN) is characterized by a rapid loss of kidney function, affecting both renal and overall patient survival. Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a small vessel
Externí odkaz:
https://doaj.org/article/d7c51c5908bb4b779dc2de2d31204ad8
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a small vessel vasculitis often leading to critical illness by multi-organ failure. Data for patients with specifically ANCA-associated renal vasculitis requiring inte
Externí odkaz:
https://doaj.org/article/ff78bf281c0742ff964a56d1437ec8cd
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundImmune checkpoint inhibitors (ICIs) are novel drugs targeting programmed cell death protein 1-ligand 1 (PD-L1) or its receptor (PD-1). Enhancing the immune system has also been associated with a wide range of immune-related adverse events (
Externí odkaz:
https://doaj.org/article/5fda8c097734485db87d67cb9220ec3d
Autor:
Ann-Kathrin Schäfer, Sascha Dierks, Moritz Schnelle, Peter Korsten, Samy Hakroush, Björn Tampe
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Plasma exchange rapidly depletes pathogenic anti-neutrophil cytoplasmic autoantibodies (ANCAs) and is considered for induction therapy in severe ANCA-associated vasculitis. The aim of plasma exchange is to remove putative disease mediators from the c
Externí odkaz:
https://doaj.org/article/80612cb656804b39b9a3e34a090f3997
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 713 (2024)
Involvement of the complement system is key to the pathogenesis of antineutrophil cytoplasmic antibody (ANCA)-associated renal vasculitis, but immunometabolic implications, especially on serum uric acid (UA) levels, still need to be elucidated. A tot
Externí odkaz:
https://doaj.org/article/67767815c70a4863826b356d6dde4ec3
Autor:
Matthias Kettwig, Katharina Ternka, Kristin Wendland, Dennis Manfred Krüger, Silvia Zampar, Charlotte Schob, Jonas Franz, Abhishek Aich, Anne Winkler, M. Sadman Sakib, Lalit Kaurani, Robert Epple, Hauke B. Werner, Samy Hakroush, Julia Kitz, Marco Prinz, Eva Bartok, Gunther Hartmann, Simone Schröder, Peter Rehling, Marco Henneke, Susann Boretius, A. Alia, Oliver Wirths, Andre Fischer, Christine Stadelmann, Stefan Nessler, Jutta Gärtner
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Studies on interferon-driven brain pathology have so far been hampered by the lack of appropriate animal models. Here the authors characterize RNASET2-deficient mice and show that neuroinflammation and brain atrophy are IFNAR1-dependent.
Externí odkaz:
https://doaj.org/article/bd1fa646273840d68762f26fc8a37047
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionAntineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a potentially life-threatening systemic small-vessel vasculitis that is characterized by pauci-immune glomerulonephritis, depicting in turn a major denominator of A
Externí odkaz:
https://doaj.org/article/8e8cbada8c9640b09866b5d0de7c7c9d
Publikováno v:
Lupus Science and Medicine, Vol 9, Iss 1 (2022)
Objective Lupus nephritis is one of the most common and serious complications of systemic lupus erythematosus (SLE). Lupus nephritis is a major cause of kidney failure in patients with SLE, attributed to increased morbidity and mortality. The in situ
Externí odkaz:
https://doaj.org/article/6ee99fafaa704d2c94dd5bda00b273f9
Publikováno v:
RMD Open, Vol 8, Iss 2 (2022)
Lupus nephritis is one of the most common and serious complications of systemic lupus erythematosus, attributed to increased morbidity and mortality. The in situ deposition of intrarenal immune complexes promote the accumulation of inflammatory cells
Externí odkaz:
https://doaj.org/article/99bd9cf3babf4151b708804d8dd14028
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
BackgroundDue to advances in cancer therapy, immune checkpoint inhibitors (ICIs) are new classes of drugs targeting programmed cell death protein 1-ligand 1 (PD-L1) or its receptor (PD-1) used in many cancer therapies. Acute interstitial nephritis (A
Externí odkaz:
https://doaj.org/article/0172e261e56b4a36a3e7ec50374ee2c2