An RNA aptamer that shifts the reduction potential of metabolic cofactors.

Autor: Samuelian JS; Department of Chemistry, Saint Louis University, St. Louis, MO, USA., Gremminger TJ; Department of Biochemistry, University of Missouri, Columbia, MO, USA.; KCAS, LLC, Shawnee, KS, USA., Song Z; Department of Biochemistry, University of Missouri, Columbia, MO, USA., Poudyal RR; Department of Biochemistry, University of Missouri, Columbia, MO, USA.; Bond Life Sciences Center, University of Missouri, Columbia, MO, USA.; Pfizer, Biomedicine Design, Cambridge, MA, USA., Li J; Department of Physics, University of Missouri, Columbia, MO, USA., Zhou Y; Department of Physics, University of Missouri, Columbia, MO, USA., Staller SA; Department of Biochemistry, University of Missouri, Columbia, MO, USA.; Laronde, Inc., Cambridge, MA, USA., Carballo JA; Department of Chemistry, Saint Louis University, St. Louis, MO, USA., Roychowdhury-Saha M; Department of Chemistry, Indiana University, Bloomington, IN, USA.; GRAIL, Menlo Park, CA, USA., Chen SJ; Department of Biochemistry, University of Missouri, Columbia, MO, USA.; Department of Physics, University of Missouri, Columbia, MO, USA.; Institute for Data Science and Informatics, University of Missouri, Columbia, MO, USA., Burke DH; Department of Biochemistry, University of Missouri, Columbia, MO, USA. burkedh@missouri.edu.; Bond Life Sciences Center, University of Missouri, Columbia, MO, USA. burkedh@missouri.edu.; Department of Biological Engineering, University of Missouri, Columbia, MO, USA. burkedh@missouri.edu.; Department of Molecular Microbiology and Immunology, University of Missouri, Columbia, MO, USA. burkedh@missouri.edu., Heng X; Department of Biochemistry, University of Missouri, Columbia, MO, USA. hengx@missouri.edu., Baum DA; Department of Chemistry, Saint Louis University, St. Louis, MO, USA. dana.baum@slu.edu.

Publikováno v: Nature chemical biology [Nat Chem Biol] 2022 Nov; Vol. 18 (11), pp. 1263-1269. Date of Electronic Publication: 2022 Sep 12.