Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Samuele Cesaro"'
Autor:
Miroslava Didiasova, Samuele Cesaro, Simon Feldhoff, Ilaria Bettin, Nana Tiegel, Vera Füssgen, Mariarita Bertoldi, Ritva Tikkanen
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 10, p 5237 (2024)
Succinic semialdehyde dehydrogenase (SSADH) is a mitochondrial enzyme involved in the catabolism of the neurotransmitter γ-amino butyric acid. Pathogenic variants in the gene encoding this enzyme cause SSADH deficiency, a developmental disease that
Externí odkaz:
https://doaj.org/article/35209843c6534c3dbabfab12d3c713ca
Autor:
Mario Cano-Muñoz, Julie Lucas, Li-Yun Lin, Samuele Cesaro, Christiane Moog, Francisco Conejero-Lara
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 5, p 2794 (2022)
Inhibition of the HIV-1 fusion process constitutes a promising strategy to neutralize the virus at an early stage before it enters the cell. In this process, the envelope glycoprotein (Env) plays a central role by promoting membrane fusion. We previo
Externí odkaz:
https://doaj.org/article/3a798f8cf97c4f2897de49f0ae0b0b83
Autor:
Mario Cano-Muñoz, Samuele Cesaro, Bertrand Morel, Julie Lucas, Christiane Moog, Francisco Conejero-Lara
Publikováno v:
Biomolecules, Vol 11, Iss 4, p 566 (2021)
A promising strategy to neutralize HIV-1 is to target the gp41 spike subunit to block membrane fusion with the cell. We previously designed a series of single-chain proteins (named covNHR) that mimic the trimeric coiled-coil structure of the gp41 N-t
Externí odkaz:
https://doaj.org/article/754f2b1ff26f4685906317111bfd0fb0
Autor:
Patrizia Polverino de Laureto, Samuele Cesaro, Massimo Stefani, Monica Bucciantini, Manuela Leri, Luana Palazzi
Publikováno v:
Biochemical pharmacology. 173
Parkinson's disease (PD) is the second most prevalent neurodegenerative disease in the elderly people. To date, drugs able to reverse the disease are not available; the gold standard is levodopa that only relieves clinical symptoms, yet with severe s