Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Samuele Calò"'
Autor:
Samuele Calò, Donatella Tondi, Alberto Venturelli, Stefania Ferrari, Piergiorgio Pecorari, Marcella Rinaldi, Stefano Ghelli, M. Paola Costi
Publikováno v:
ARKIVOC, Vol 2004, Iss 5, Pp 382-396 (2004)
Externí odkaz:
https://doaj.org/article/327ff35b7ce14240bab26364dad47b8d
Autor:
Paul A.M. Michels, Domantas Motiejunas, Véronique Hannaert, M. Paola Costi, Samuele Calò, Erika Nerini, Shreedhara Gupta, Alberto Venturelli, Stefan Henrich, Sandra Lazzari, Rosaria Luciani, Stefania Ferrari, Rebecca C. Wade, Federica Morandi
Publikováno v:
ResearcherID
Folate analogue inhibitors of Leishmania major pteridine reductase (PTR1) are potential antiparasitic drug candidates for combined therapy with dihydrofolate reductase (DHFR) inhibitors. To identify new molecules with specificity for PTR1, we carried
Autor:
Donatella Tondi, Maria Paola Costi, Alberto Venturelli, Stefania Ferrari, Daniela Barlocco, Samuele Calò
Publikováno v:
Current Medicinal Chemistry. 12:2241-2258
Recent methodologies applied to the drug discovery process, such as genomics and proteomics, have greatly implemented our basic understanding of drug action and are giving more input to medicinal chemists, in finding genuinely new targets and opportu
Autor:
Stefano Mangani, Luca Costantino, Rosaria Luciani, Flavio Di Pisa, Samuele Calò, Stefania Ferrari, Cecilia Pozzi, Susan Sammak, Rosalida Leone, M. Paola Costi
Thymidylate synthase (TS) is a target for antifolate-based chemotherapies of microbial and human diseases. Here, ligand-based, synthetic, and X-ray crystallography studies led to the discovery of 6-(3-cyanobenzoyloxy)-2-oxo-2H-naphto[1,8-bc]furan, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::327cb7b4a33102f834aadd455264633c
http://pubs.acs.org/doi/abs/10.1021/jm4014086
http://pubs.acs.org/doi/abs/10.1021/jm4014086
Publikováno v:
Bioorganicmedicinal chemistry letters. 20(11)
A small set of boronic acids acting as low nanomolar inhibitors of AmpC beta-lactamase were designed and synthesized in the effort to improve affinity, pharmacokinetic properties, and to provide a valid lead compound. X-ray crystallography revealed t
Autor:
Federica Pellati, Paola Nieri, Stefania Benvenuti, Barbara Adinolfi, Samuele Calò, Michele Melegari
Publikováno v:
Phytochemistry. 67(13)
Bioassay-guided fractionation of n -hexane extracts of Echinacea pallida (Asteraceae) roots led to the isolation and structure elucidation of two polyacetylenes ( 1 , 3 ) and three polyenes ( 2 , 4 , 5 ). Two are known hydroxylated compounds, namely
Autor:
Valentina Buzzoni, Samuele Calò, Alberto Venturelli, Jesús Blázquez, Stefania Ferrari, M. Paola Costi
Publikováno v:
Bioorganicmedicinal chemistry letters. 14(15)
With the aim of improving the ability of non-beta-lactam inhibitors to inhibit AmpC-beta-lactamase, a series of 3-aza-phenyl-boronic acid derivatives was obtained using in parallel synthesis. The molecules were tested against Escherichia coli AmpC-be
Publikováno v:
Diversity, Vol 13, Iss 8, p 374 (2021)
Considering the rapid growth of tourism in recent years and the acknowledgement that exposure to solar UV radiation may cause skin cancer, sunscreens have been widely used by beachgoers in recent decades. UV filters contained in sunscreens, however,
Externí odkaz:
https://doaj.org/article/c4419268cd18486f96a2d7312c11b09c