Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Samuele, Melis"'
Autor:
Gian Luigi Gessa, Giancarlo Colombo, Daniela Molinari, Roberto Seghizzi, Giuliana Brunetti, Ezio Bombardelli, Giovanni Vacca, Salvatore Serra, Mauro A.M. Carai, Paolo Morazzoni, Samuele Melis
Publikováno v:
Phytotherapy Research. 17:537-541
A previous study demonstrated that an extract of Salvia miltiorrhiza, a medicinal herb highly valued in Chinese folk medicine for the treatment of different pathologies, including insomnia, was capable of reducing voluntary alcohol intake in selectiv
Autor:
Giovanni Vacca, Salvatore Serra, Gian Luigi Gessa, Giuliana Brunetti, Giancarlo Colombo, Samuele Melis, Mauro A.M. Carai
Publikováno v:
European Journal of Pharmacology. 433:101-104
The present study investigated the effect of the administration of the GABA(B) receptor antagonists, SCH 50911 [(2S)(+)-5,5-dimethyl-2-morpholineacetic acid], CGP 46381 [(3-aminopropyl)(cyclohexylmethyl)phosphinic acid] and CGP 52432 (3-[[(3,4-dichlo
Autor:
Mauro A.M. Carai, Giovanni Vacca, Salvatore Serra, Giuliana Brunetti, Giancarlo Colombo, Angelo M. Pistuddi, Gian Luigi Gessa, Costantino Solinas, Giorgio Cignarella, Giovanna Minardi, Samuele Melis, Sarah Mastinu
Publikováno v:
European Journal of Pharmacology. 428:315-321
The present study was aimed at identifying the receptor systems involved in the mediation of the sedative/hypnotic effect of γ-hydroxybutyric acid (GHB) in DBA mice. Administration of the putative antagonist of the GHB binding site, 6,7,8,9-tetrahyd
Autor:
Mauro A.M. Carai, Gian Luigi Gessa, Giuliana Brunetti, Raquel Gómez, Samuele Melis, Giovanni Vacca, Salvatore Serra, Giancarlo Colombo
Publikováno v:
Psychopharmacology. 159:181-187
Rationale: Recent studies have shown that the cannabinoid CB1 receptor antagonist, SR 141716, is capable of reducing voluntary ethanol intake in rodents, suggesting the involvement of the CB1 receptor in the neural circuitry mediating the positive re
Autor:
Marialaura Pani, Giovanni Vacca, Salvatore Serra, Mauro A.M. Carai, Gian Luigi Gessa, Giacomo Diaz, Giuliana Brunetti, Carla Lobina, Giancarlo Colombo, Samuele Melis
Publikováno v:
Brain Research Protocols. 8:74-81
The exogenous administration of γ-hydroxybutyric acid (GHB), a constituent of the mammalian brain where it likely functions as a neurotransmitter or a neuromodulator, exerts a number of pharmacological effects, including sedation and hypnosis. The p
Autor:
Gian Luigi Gessa, Giuliana Brunetti, Samuele Melis, Giancarlo Colombo, Raquel Gómez, Giovanni Vacca, Salvatore Serra, Mauro A.M. Carai
Publikováno v:
European Journal of Pharmacology. 430:369-371
The cannabinoid CB1 receptor antagonist, N-piperidino-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-3-pyrazole-carboxamide) (SR 141716); 0.3–3 mg/kg, i.p., twice daily for 10 days), prevented the acquisition of alcohol drinking behavior in rat
Autor:
Giovanni, Vacca, Giancarlo, Colombo, Giuliana, Brunetti, Samuele, Melis, Daniela, Molinari, Salvatore, Serra, Roberto, Seghizzi, Paolo, Morazzoni, Ezio, Bombardelli, Gian Luigi, Gessa, Mauro A M, Carai
Publikováno v:
Phytotherapy research : PTR. 17(5)
A previous study demonstrated that an extract of Salvia miltiorrhiza, a medicinal herb highly valued in Chinese folk medicine for the treatment of different pathologies, including insomnia, was capable of reducing voluntary alcohol intake in selectiv
Autor:
Mauro A.M. Carai, Gian Luigi Gessa, Giovanni Vacca, Salvatore Serra, Giancarlo Colombo, Samuele Melis
Publikováno v:
Alcohol and alcoholism (Oxford, Oxfordshire). 37(2)
Previous experiments demonstrated that the selectively bred Sardinian alcohol-preferring (sP) rats possess a genetically based proclivity to consume pharmacologically relevant doses of gamma-hydroxybutyric acid (GHB). The present study was aimed at c