Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Samuel Waldner"'
Publikováno v:
SoftwareX, Vol 27, Iss , Pp 101796- (2024)
We present a deep-learning-based software pipeline for reconstructing and segmenting large sets of time-resolved micro-computed tomography (µCT) image data. We construct and train a convolutional neural network (CNN) to consistently, rapidly, and au
Externí odkaz:
https://doaj.org/article/e351302dcc6f4fe29b371879b8425e4e
Autor:
Samuel Waldner, Erwin Wendelspiess, Pascal Detampel, Christian M. Schlepütz, Jörg Huwyler, Maxim Puchkov
Publikováno v:
Heliyon, Vol 10, Iss 4, Pp e26025- (2024)
The mechanism governing pharmaceutical tablet disintegration is far from fully understood. Despite the importance of controlling a formulation's disintegration process to maximize the active pharmaceutical ingredient's bioavailability and ensure pred
Externí odkaz:
https://doaj.org/article/053037ade64e40188a124f8ed7a23ecb
Autor:
Jan Stephan Bolten, Christine Tanner, Griffin Rodgers, Georg Schulz, Soledad Levano, Timm Weitkamp, Samuel Waldner, Ramya Deepthi Puligilla, Daniel Bodmer, Bert Müller, Jörg Huwyler
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0284562 (2023)
Nephrotoxicity is an important drug safety aspect to be assessed during drug discovery and development. To study renal toxicity, in vitro cell-based assays are often used. Unfortunately, translating the results of such cell assays to vertebrates incl
Externí odkaz:
https://doaj.org/article/704316967a424cb0acc9a205ec2a8f5e
Autor:
Andreas Schittny, Samuel Waldner, Urs Duthaler, Alexander Vorobyev, Rimma Abramovich, Stephan Krähenbühl, Maxim Puchkov, Jörg Huwyler
Publikováno v:
Pharmaceutics, Vol 13, Iss 3, p 401 (2021)
Amorphous solid dispersions (ASDs) are a promising drug-delivery strategy to overcome poor solubility through formulation. Currently, the understanding of drug absorption mechanisms from ASDs in humans is incomplete. Aiming to gain insights in this m
Externí odkaz:
https://doaj.org/article/534e595be6d94f1ab915b5f71e0c19ac
Autor:
Urs Duthaler, Samuel Waldner, Maxim Puchkov, Andreas Schittny, Jörg Huwyler, R. A. Abramovich, Alexander Vorobyev, Stephan Krähenbühl
Publikováno v:
Pharmaceutics
Pharmaceutics, Vol 13, Iss 401, p 401 (2021)
Volume 13
Issue 3
Pharmaceutics, Vol 13, Iss 401, p 401 (2021)
Volume 13
Issue 3
Amorphous solid dispersions (ASDs) are a promising drug-delivery strategy to overcome poor solubility through formulation. Currently, the understanding of drug absorption mechanisms from ASDs in humans is incomplete. Aiming to gain insights in this m