Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Samuel W. J. Shields"'
Publikováno v:
SynOpen, Vol 02, Iss 02, Pp 0168-0175 (2018)
Abstract The total synthesis of isotopically labelled (9R,10S)-dihydrosterculic acid, a usual cyclopropane fatty acid with biologically relevant toxicity upon desaturation in vivo, is reported. A diastereoselective Corey–Chaykovsky reaction was
Externí odkaz:
https://doaj.org/article/2d3c7bfe259b46c889a94febc691f7ac
Autor:
Christian A. Rosales, Samuel W. J. Shields, Chelsey L. J. Aulenback, Gazmend Elezi, Karl V. Wasslen, Peter J. Pallister, Kym F. Faull, Jeffrey M. Manthorpe, Jeffrey C. Smith
Publikováno v:
Journal of the American Society for Mass Spectrometry. 34:948-957
Autor:
Molly S. Blevins, Samuel W. J. Shields, Wei Cui, Wedad Fallatah, Ann B. Moser, Nancy E. Braverman, Jennifer S. Brodbelt
Publikováno v:
Analytical Chemistry. 94:12621-12629
The biological impact of ether glycerophospholipids (GP) in peroxisomal disorders and other diseases makes them significant targets as biomarkers for diagnostic assays or deciphering pathology of the disorders. Ether lipids include both plasmanyl and
Publikováno v:
Analytical Chemistry. 94:11352-11359
Understanding and elucidating the diverse structures and functions of lipids has motivated the development of many innovative tandem mass spectrometry (MS/MS) strategies. Higher-energy activation methods, such as ultraviolet photodissociation (UVPD),
Autor:
Woo-Ok Jung, Binh Khanh Mai, Minjin Yoo, Samuel W. J. Shields, Jason R. Zbieg, Craig E. Stivala, Peng Liu, Michael J. Krische
Publikováno v:
ACS Catal
The mechanism of π-allyliridium C,O-benzoate-catalyzed allylic amination was studied by (a) reaction progress kinetic analysis (RPKA), (b) tandem ESI-MS analysis, and (c) computational studies involving density functional theory (DFT) calculations.
Autor:
Scott A. McLuckey, Jeffrey C. Smith, Elissia T. Franklin, Jeffrey M. Manthorpe, Samuel W. J. Shields, Yu Xia
Publikováno v:
J Am Soc Mass Spectrom
Shotgun lipidomics provides sensitive and fast lipid identification without the need for chromatographic separation. Challenges faced by shotgun analysis of glycerophospholipids (GPs) include the lack of signal uniformity across GP classes and the in
Autor:
Yu‐An Kuo, Cheulhee Jung, Yu‐An Chen, Hung‐Che Kuo, Oliver S. Zhao, Trung D. Nguyen, James R. Rybarski, Soonwoo Hong, Yuan‐I Chen, Dennis C. Wylie, John A. Hawkins, Jada N. Walker, Samuel W. J. Shields, Jennifer S. Brodbelt, Jeffrey T. Petty, Ilya J. Finkelstein, Hsin‐Chih Yeh
NanoCluster Beacons (NCBs) are multicolor silver nanocluster probes whose fluorescence can be activated or tuned by a proximal DNA strand called the activator. While a single-nucleotide difference in a pair of activators can lead to drastically diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::807e302043c7c4a15261ec93940a523c
https://doi.org/10.1101/2021.12.04.471212
https://doi.org/10.1101/2021.12.04.471212
Autor:
Yu‐An Kuo, Cheulhee Jung, Yu‐An Chen, Hung‐Che Kuo, Oliver S. Zhao, Trung D. Nguyen, James R. Rybarski, Soonwoo Hong, Yuan‐I Chen, Dennis C. Wylie, John A. Hawkins, Jada N. Walker, Samuel W. J. Shields, Jennifer S. Brodbelt, Jeffrey T. Petty, Ilya J. Finkelstein, Hsin‐Chih Yeh
Publikováno v:
Advanced Materials. 34:2270286
Autor:
Christian A. Rosales, Joshua A. Roberts, Jeffrey C. Smith, Samuel W. J. Shields, Peter J. Pallister, Jeffrey M. Manthorpe, Karl V. Wasslen
Publikováno v:
Analytical chemistry. 93(2)
Trimethylation enhancement using diazomethane (TrEnDi) is a derivatization technique that significantly enhances the signal intensity of glycerophospholipid species in mass spectrometry (MS) and tandem mass spectrometry (MS/MS) analyses. Here, we des
Autor:
David Overy, Rajagopal Subramaniam, Kristina Shostak, John Vierula, Christopher Bonner, Amanda Sproule, Indira Thapa, Barbara A. Blackwell, Samuel W. J. Shields
Publikováno v:
Molecular microbiologyREFERENCES. 114(4)
In F. graminearum, the transcription factor TRI6 positively regulates the trichothecene biosynthetic gene cluster (BGC) leading to the production of the secondary metabolite 15-acetyl deoxynivalenol. Secondary metabolites are not essential for surviv