Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Samuel W, Schaffter"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Molecular biosensors that accurately measure protein concentrations without external equipment are critical for solving numerous problems in diagnostics and therapeutics. Modularly transducing the binding of protein antibodies, protein switc
Externí odkaz:
https://doaj.org/article/a4d9604f50f246d4a1188d8f1ec761f6
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Gaining control over crystallization processes is challenging. Herein, the authors describe a protocol for the controlled growth of DNA nanotubes by feedback regulation: the coupling of a reversible bimolecular monomer buffering reaction delivers the
Externí odkaz:
https://doaj.org/article/7694235319dd4daeba447ac6fd30051b
Autor:
Kuan-Lin Chen, Jackson O'Brien, Madeline Noble, Arvind Murugan, Samuel W. Schaffter, Rebecca Schulman
Publikováno v:
Nature Chemistry. 14:1224-1232
Engineered far-from-equilibrium synthetic chemical networks that pulse or switch states in response to environmental signals could precisely regulate the kinetics of chemical synthesis or self-assembly pathways. Currently, such networks must be exten
Cotranscriptionally encoded RNA strand displacement (ctRSD) circuits are an emerging tool for programmable molecular computation with potential applications spanningin vitrodiagnostics to continuous computation inside living cells. In ctRSD circuits,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0f00d273100789358801b5acb05deff
https://doi.org/10.1101/2023.02.01.526534
https://doi.org/10.1101/2023.02.01.526534
Autor:
Deepak K. Agrawal, Terence M. Murphy, Joanna Schneider, Samuel W. Schaffter, Eric Rothchild, Michael S. Pacella, Rebecca Schulman
Publikováno v:
ACS Nano. 14:13451-13462
Molecular assemblies inside cells often undergo structural reconfiguration in response to stimuli to alter their function. Adaptive reconfiguration of cytoskeletal networks, for example, enables cellular shape change, movement, and cargo transport an
Engineered molecular circuits that process information in biological systems could address emerging human health and biomanufacturing needs. However, such circuits can be difficult to rationally design and scale. DNA-based strand displacement reactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce97fdd8622405cfdedbe3fe927e1d6c
https://doi.org/10.1101/2021.07.20.450530
https://doi.org/10.1101/2021.07.20.450530
Publikováno v:
Current Dermatology Reports. 8:14-25
To summarize the use of nanotechnology-based drug delivery systems for psoriasis therapies, focusing on recent studies of treatment efficacy in humans and murine models. Both topical and oral psoriasis medications, in addition to alternative psoriasi
Autor:
Samuel W. Schaffter, Kuan-Lin Chen, Jackson O’Brien, Madeline Noble, Arvind Murugan, Rebecca Schulman
Publikováno v:
Nature Chemistry. 14:1335-1335
Autor:
Samuel W, Schaffter, Joanna, Schneider, Deepak K, Agrawal, Michael S, Pacella, Eric, Rothchild, Terence, Murphy, Rebecca, Schulman
Publikováno v:
ACS nano. 14(10)
Molecular assemblies inside cells often undergo structural reconfiguration in response to stimuli to alter their function. Adaptive reconfiguration of cytoskeletal networks, for example, enables cellular shape change, movement, and cargo transport an
Autor:
Hari K. K. Subramanian, Samuel W. Schaffter, Elisa Franco, Joanna Schneider, Rebecca Schulman, Leopold N. Green
Publikováno v:
Nucleic Acids Research
The use of proteins that bind and catalyze reactions with DNA alongside DNA nanostructures has broadened the functionality of DNA devices. DNA binding proteins have been used to specifically pattern and tune structural properties of DNA nanostructure