Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Samuel Vega Estevez"'
Autor:
Jessica Fletcher, James O'Connor-Moneley, Dean Frawley, Peter R Flanagan, Leenah Alaalm, Pilar Menendez-Manjon, Samuel Vega Estevez, Shane Hendricks, Andrew L Woodruff, Alessia Buscaino, Matthew Z Anderson, Derek J Sullivan, Gary P Moran
Publikováno v:
PLoS Genetics, Vol 19, Iss 12, p e1011082 (2023)
The Candida albicans genome contains between ten and fifteen distinct TLO genes that all encode a Med2 subunit of Mediator. In order to investigate the biological role of Med2/Tlo in C. albicans we deleted all fourteen TLO genes using CRISPR-Cas9 mut
Externí odkaz:
https://doaj.org/article/6874864e6b33490da8798f1d41d1bd22
Autor:
Marzia Rizzo, Natthapon Soisangwan, Jan Soetaert, Samuel Vega-Estevez, Anna Selmecki, Alessia Buscaino
Stress-induced genome instability in microbial organisms is emerging as a critical regulatory mechanism for driving rapid and reversible adaption to drastic environmental changes. In Candida albicans, a human fungal pathogen that causes life-threaten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee712ae0ae8d3c2d1db9dcc5ab18dc35
https://doi.org/10.1101/2021.12.06.471441
https://doi.org/10.1101/2021.12.06.471441
Autor:
Marzia Rizzo, Natthapon Soisangwan, Samuel Vega-Estevez, Robert Jordan Price, Chloe Uyl, Elise Iracane, Matt Shaw, Jan Soetaert, Anna Selmecki, Alessia Buscaino
Publikováno v:
PLOS Genetics. 18:e1010576
A delicate balance between genome stability and instability ensures genome integrity while generating genetic diversity, a critical step for evolution. Indeed, while excessive genome instability is harmful, moderated genome instability can drive adap