Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Samuel T. Pellom"'
Autor:
Samuel T. Pellom, Claire Smalley Rumfield, Y. Maurice Morillon II, Nicholas Roller, Lisa K. Poppe, Douglas E. Brough, Helen Sabzevari, Jeffrey Schlom, Caroline Jochems
Publikováno v:
JCI Insight, Vol 6, Iss 7 (2021)
There are approximately 44,000 cases of human papillomavirus–associated (HPV-associated) cancer each year in the United States, most commonly caused by HPV types 16 and 18. Prophylactic vaccines successfully prevent healthy people from acquiring HP
Externí odkaz:
https://doaj.org/article/23d2fa7a4ec74f2a9d94ecf908385524
Autor:
Y. Maurice Morillon, Claire Smalley Rumfield, Samuel T. Pellom, Ariana Sabzevari, Nicholas T. Roller, Lucas A. Horn, Caroline Jochems, Claudia Palena, John W. Greiner, Jeffrey Schlom
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
The lack of serial biopsies in patients with a range of carcinomas has been one obstacle in our understanding of the mechanism of action of immuno-oncology agents as well as the elucidation of mechanisms of resistance to these novel therapeutics. Whi
Externí odkaz:
https://doaj.org/article/17c83c0e943345a1970124ea7637a98b
Autor:
Caroline Jochems, Sarah R. Tritsch, Karin M. Knudson, Sofia R. Gameiro, Claire Smalley Rumfield, Samuel T. Pellom, Y. Maurice Morillon, Robby Newman, Warren Marcus, Christopher Szeto, Shahrooz Rabizadeh, Hing C. Wong, Patrick Soon-Shiong, Jeffrey Schlom
Publikováno v:
OncoImmunology, Vol 8, Iss 2 (2019)
Here we describe a novel bifunctional fusion protein, designated N-809. This molecule comprises the IL-15/IL15Rα superagonist complex containing the Fc-domain of IgG1 (N-803, formerly designated as ALT-803) fused to two single chain anti-PD-L1 domai
Externí odkaz:
https://doaj.org/article/44c44230f6754047981633a4bd819a06
Publikováno v:
Clinical Medicine Insights: Gastroenterology, Vol 2015, Iss 8, Pp 29-44 (2015)
Externí odkaz:
https://doaj.org/article/8655eafb47054d039f2fb7eb10fe5348
Autor:
Thomas J. Sayers, Dan L. Longo, William J. Murphy, Daniel W. McVicar, Hideo Yagita, Alan D. Brooks, Rachel L. de Kluyver, Menaka C. Thounaojam, Duafalia F. Dudimah, Samuel T. Pellom, Anil Shanker
Cancer immunotherapy shows great promise but many patients fail to show objective responses, including in cancers that can respond well, such as melanoma and renal adenocarcinoma. The proteasome inhibitor bortezomib sensitizes solid tumors to apoptos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c2d10a5b3584ba5c29a7d7591ec47ca
https://doi.org/10.1158/0008-5472.c.6507486.v1
https://doi.org/10.1158/0008-5472.c.6507486.v1
Autor:
Thomas J. Sayers, Dan L. Longo, William J. Murphy, Daniel W. McVicar, Hideo Yagita, Alan D. Brooks, Rachel L. de Kluyver, Menaka C. Thounaojam, Duafalia F. Dudimah, Samuel T. Pellom, Anil Shanker
Calreticulin expression on bortezomib-treated tumor cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::328acbc375c77ffdc243cddb3ec9e979
https://doi.org/10.1158/0008-5472.22408215
https://doi.org/10.1158/0008-5472.22408215
Autor:
Thomas J. Sayers, Dan L. Longo, William J. Murphy, Daniel W. McVicar, Hideo Yagita, Alan D. Brooks, Rachel L. de Kluyver, Menaka C. Thounaojam, Duafalia F. Dudimah, Samuel T. Pellom, Anil Shanker
Legends for Supplementary Figures S1-S3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f36cfd0a66cb7c0cd9f4f2cf6b4196e
https://doi.org/10.1158/0008-5472.22408224
https://doi.org/10.1158/0008-5472.22408224
Publikováno v:
Cancer Causes & Control. 31:795-800
Breast cancer is a commonly diagnosed malignancy and the second leading cause of cancer-related death among American women today. The literature suggests that African American Women (AAW) are more likely to die from the disease each year compared to
Autor:
Helen Sabzevari, Jeffrey Schlom, Nicholas Roller, Samuel T. Pellom, Claire Smalley Rumfield, Douglas E. Brough, Caroline Jochems, Lisa K. Poppe, Y. Maurice Morillon
Publikováno v:
JCI Insight
JCI Insight, Vol 6, Iss 7 (2021)
JCI Insight, Vol 6, Iss 7 (2021)
There are approximately 44,000 cases of human papillomavirus–associated (HPV-associated) cancer each year in the United States, most commonly caused by HPV types 16 and 18. Prophylactic vaccines successfully prevent healthy people from acquiring HP
Autor:
Caroline Jochems, Nicole Toney, Claire Smalley Rumfield, James L. Gulley, Renee N. Donahue, Samuel T. Pellom, Yo-Ting Tsai, Jeffrey Schlom, Julius Strauss
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background The safety and efficacy of bintrafusp alfa, a first-in-class bifunctional fusion protein composed of the extracellular domain of the TGF-βRII receptor (a TGF-β ‘trap’) fused to a human IgG1 mAb blocking PD-L1, have been demonstrated