Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Samuel Sprowls"'
Autor:
Christopher Hubert, Kelly Mitchell, Samuel Sprowls, Sajina Shakya, Sonali Arora, Daniel J. Silver, Christopher M. Goins, Lisa Wallace, Gustavo Roversi, Rachel Schafer, Kristen Kay, Tyler E. Miller, Adam Lauko, John Bassett, Anjali Kashyap, J. D’Amato Kass, Erin E. Mulkearns-Hubert, Sadie Johnson, Joseph Alvarado, Jeremy N. Rich, Patrick J. Paddison, Anoop P. Patel, Shaun R. Stauffer, Christopher G. Hubert, Justin D. Lathia
Publikováno v:
Journal of Clinical and Translational Science, Vol 7, Pp 107-107 (2023)
OBJECTIVES/GOALS: Glioblastomas (GBMs) are heterogeneous, treatment-resistant tumors that are driven by populations of cancer stem cells (CSCs). In this study, we perform an epigenetic-focused functional genomics screen in GBM organoids and identify
Externí odkaz:
https://doaj.org/article/38b0f34846504b9fac37c7e24f076612
Autor:
Christopher Butler, Samuel Sprowls, Gabor Szalai, Tasneem Arsiwala, Pushkar Saralkar, Benjamin Straight, Shea Hatcher, Evan Tyree, Michael Yost, William J. Kohler, Benjamin Wolff, Emily Putnam, Paul Lockman, Tuoen Liu
Publikováno v:
Translational Oncology, Vol 13, Iss 6, Pp - (2020)
Breast cancer patients presenting with symptomatic brain metastases have poor prognosis, and current chemotherapeutic agents are largely ineffective. In this study, we evaluated the hypomethylating agent azacitidine (AZA) for its potential as a novel
Externí odkaz:
https://doaj.org/article/ebf2afac0990498984f62850b8f84d41
Autor:
Dionysios Watson, Defne Bayik, Adam Lauko, Samuel Sprowls, Gauravi Deshpande, Sarah Wilifford, Katie Troike, Daniel Silver, Sabrina Wang, Juliana Seder, Kristen Kay, Anita Hjelmeland, Justin Lathia
Publikováno v:
Neuro-Oncology. 24:vii286-vii287
Mitochondrial transfer occurs both in stroke (central nervous system) and inflammatory pain (peripheral nerves). However, its role in glioblastoma (GBM) remains poorly understood. We hypothesized that mitochondrial transfer from non-malignant to GBM