Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Samuel Shek"'
Autor:
Jun Li, A. Keith Tanswell, Rosetta Belcastro, Samuel Shek, Azhar Masood, Crystal Kantores, Ben-Hur Johnson, Robert P. Jankov, Adrian J A Ziino, Man Yi
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 300:L319-L329
During early postnatal alveolar formation, the lung tissue of rat pups undergoes a physiological remodeling involving apoptosis of distal lung cells. Exposure of neonatal rats to severe hyperoxia (≥95% O2) both arrests lung growth and results in in
Autor:
Patrick J. McNamara, Man Yi, Samuel Shek, Robert P. Jankov, Mandy Lau, Rosetta Belcastro, Brian P. Kavanagh, Crystal Kantores, A. Keith Tanswell, Jaques Belik, Jingyi Pan, Azhar Masood
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 297:L920-L930
Permissive hypercapnia, achieved using low tidal volume ventilation, has been an effective protective strategy in patients with acute respiratory distress syndrome. To date, no such protective effect has been demonstrated for the chronic neonatal lun
Autor:
Man Yi, A. Keith Tanswell, Samuel Shek, Jun Li, Robert P. Jankov, Rosetta Belcastro, Crystal Kantores, Ben-Hur Johnson, Azhar Masood
Publikováno v:
Pediatric Research. 66:260-265
IL-1 beta, a proinflammatory cytokine, may contribute to the development of the chronic neonatal lung injury, bronchopulmonary dysplasia. Chronic neonatal lung injury was induced in rats, by exposure to 60% O2 for 14 d from birth, to determine whethe
Autor:
Man Yi, A. Keith Tanswell, Judy Cabacungan, Azhar Masood, Sanna Padela, Robert P. Jankov, Samuel Shek, Rosetta Belcastro
Publikováno v:
Pediatric Research. 63:232-238
Mesenchymal cell-derived FGF-7 (fibroblast growth factor-7) induces proliferation in both epithelial and endothelial cells. We found FGF-7 to be expressed in the lungs of neonatal rats from birth to d 14 of age. A role for FGF-7 in early postnatal lu
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 174:581-589
Fibroblast growth factor receptor-1alpha(IIIc) [FGF-R1alpha(IIIc)] regulates recovery of neonatal rat lung growth, after 95% oxygen-mediated growth arrest. Its role in normal postnatal alveologenesis is unknown.To determine if FGF-R1alpha(IIIc) regul
Autor:
Sanna Padela, Judy Cabacungan, A. Keith Tanswell, Samuel Shek, Rosetta Belcastro, Robert P. Jankov, Man Yi
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 172:907-914
Our core hypothesis is that growth factors that have dysregulated expression during experimental neonatal lung injury are likely to be involved in normal postnatal lung growth and alveologenesis.To determine if hepatocyte growth factor (HGF) is upreg
Autor:
Samuel Shek, Richard L. Auten, Martin Post, Ian B. Copland, Robert P. Jankov, Rosetta Belcastro, A. Keith Tanswell, Man Yi, Daryl Humes, Kurt H. Albertine, Neil B. Sweezey
Publikováno v:
American journal of respiratory and critical care medicine. 170(11)
The lungs of newborn rats exposed to 60% oxygen for 14 days develop an injury that shares morphologic similarities to human bronchopulmonary dysplasia (BPD). Neutrophil influx into the lung, as part of an inflammatory response, may play a pivotal rol