Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Samuel S. Wong"'
Autor:
G Reda Hanna, Paul W. Erhardt, Mark E. Sullivan, William C. Lumma, Samuel S. Wong, John W. Lampe
Publikováno v:
Journal of Medicinal Chemistry. 32:688-693
A series of heterocyclic N-[(diethylamino)alkyl]arenamides related to acecainide was prepared and examined for antiarrhythmic activity. The compounds were synthesized from the corresponding known heterocyclic carboxylic acids or esters by using stand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f29e04a6bc65c4b8dac76cd63917f0
https://doi.org/10.1021/jm00123a033
https://doi.org/10.1021/jm00123a033
Publikováno v:
European Journal of Pharmacology. 100:321-327
The effects of the monocarboxylic ionophore, salinomycin (K+-selective), on isometric twitches, high K+-induced contracture and transmembrane action potentials were compared with those of the monocarboxylic ionophore, monensin (Na+-selective), in iso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ac944104fc0c978d7f1016538e22ad
https://doi.org/10.1016/0014-2999(84)90008-6
https://doi.org/10.1016/0014-2999(84)90008-6
Publikováno v:
European Journal of Pharmacology. 80:323-329
The electrophysiologic effects of encainide were determined in normal and acutely ischemic (30 min) rabbit ventricular muscle cells. Encainide (10(-6), 5 X 10(-6) and 10(-5) M) had no effect on resting potential (RP); 10(-6) M encainide reduced overs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e0657cfa207a8d029a59008fee18a67
https://doi.org/10.1016/0014-2999(82)90077-2
https://doi.org/10.1016/0014-2999(82)90077-2
Autor:
Mark E. Sullivan, Ronald A. Wohl, Chung Nan Wan, Anthony J. Marisca, David D. Davey, Thomas Kenneth Morgan, William C. Lumma, Samuel S. Wong, Robert P. Gomez, Martha Briggs
Publikováno v:
Journal of Medicinal Chemistry. 29:1398-1405
The syntheses of seven 4-(substituted phenyl)but-2-en(or yn)yl quaternary ammonium salts and four related tertiary amines are described. The Meerwein arylation reaction was the preferred synthetic method for the required intermediate 1-aryl-4-halo-2-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a69fbac3ec0ef6812fa30c74eab0bed0
https://doi.org/10.1021/jm00158a014
https://doi.org/10.1021/jm00158a014
Autor:
Kristina Epstein, Arthur L. Bassett, Robert J. Myerburg, Marion S. Gaide, John S. Cameron, Samuel S. Wong
Publikováno v:
European Journal of Pharmacology. 90:283-287
The effects of verapamil (0.1–4.0 μg/ml) on transmembrane action potential configuration was examined in various regions of the normal cat left ventricular endocardium. Surface electrograms showed that the sequence of activation of anterior papill
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d56aeb80cbfd8b062b3ee7f1b1a2c9f5
https://doi.org/10.1016/0014-2999(83)90251-0
https://doi.org/10.1016/0014-2999(83)90251-0
Electrophysiologic consequences of chronic experimentally induced left ventricular pressure overload
Autor:
Paul A. Guse, Kristina Epstein, Samuel S. Wong, Henry Gelband, Marion S. Gaide, T. Ralph Alvarez, Arthur L. Bassett, John S. Cameron, Robert J. Myerburg
Publikováno v:
Journal of the American College of Cardiology. (3):481-487
Cardiac electrophysiologic alterations were evaluated 1 to 8 months after partial supracoronary aortic constriction in cats. This procedure induced left ventricular systolic hypertension and hypertrophy with marked connective tissue infiltration. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7c35202107ce7f98e7e7fe3b519629b
Autor:
Arthur L. Bassett, Robert J. Myerburg, Patricia L. Kozlovskis, John S. Cameron, Robert W. Rubin, Samuel S. Wong, Marion S. Gaide, J.D. Silver
Publikováno v:
Journal of molecular and cellular cardiology. 16(6)
Densitometric scanning of SDS-polyacrylamide gels was used to measure myosin heavy chain concentration in left ventricular specimens obtained from cat heart 3 to 12 months after healing of small experimental myocardial infarctions. The study was desi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f34253912cd1159d575a585660d62db
https://pubmed.ncbi.nlm.nih.gov/6748090
https://pubmed.ncbi.nlm.nih.gov/6748090
Autor:
J. Wiggins, Samuel S. Wong, Mark E. Sullivan, Robert J. DeVita, Thomas M. Argentieri, Anthony J. Marisca, T. K. Jun. Morgan, David D. Davey, Robert P. Gomez, R. A. Wohl, W. C. Jun. Lumma, H. J. Reiser, V. K. Jain
Publikováno v:
ChemInform. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93429ab961ab89bb32ef050791f7a7e6
https://doi.org/10.1002/chin.198746155
https://doi.org/10.1002/chin.198746155
Autor:
Samuel S. Wong, Robert P. Gomez, R. A. Wohl, Anthony J. Marisca, W. C. Jun. Lumma, Mark E. Sullivan, T. K. Jun. Morgan, M. Briggs, David D. Davey, C.-N. Wan
Publikováno v:
ChemInform. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::010aa9e6240e84e94d61c971c3486568
https://doi.org/10.1002/chin.198703141
https://doi.org/10.1002/chin.198703141
Autor:
Kristina Epstein, Arthur L. Bassett, Samuel S. Wong, M. Nadji, Robert J. Myerburg, Henry Gelband, Azorides R. Morales, Alan M. Ezrin, Marion S. Gaide
Publikováno v:
Archives internationales de physiologie et de biochimie. 89(5)
(2 figures)The effect of coronary artery ligation on electrophysiologic properties of cat ventricular muscle cells was studied. Depression of resting potential, action potential rate of rise and amplitude was observed in infarcted cells, 30 min to 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7715b6e092459a5adacbaa0dd9a65860
https://pubmed.ncbi.nlm.nih.gov/6176198
https://pubmed.ncbi.nlm.nih.gov/6176198