Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Samuel S. Newton"'
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders with strong genetic heterogeneity and more prevalent in males than females. Recent human genetic studies have identified multiple high-risk genes for ASD, which produce similar
Externí odkaz:
https://doaj.org/article/a2d5b8fd77a7429181a0fae035206247
Publikováno v:
Life, Vol 13, Iss 9, p 1826 (2023)
Trophic factors are secreted proteins that can modulate neuronal integrity, structure, and function. Previous preclinical studies have shown synergistic effects on decreasing apoptosis and improving behavioral performance after stroke when combining
Externí odkaz:
https://doaj.org/article/4ea63d6cb0734886bfc3be67e6ecbc30
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11507 (2023)
Cerebral hypoperfusion is associated with enhanced cognitive decline and increased risk of neuropsychiatric disorders. Erythropoietin (EPO) is a neurotrophic factor known to improve cognitive function in preclinical and clinical studies of neurodegen
Externí odkaz:
https://doaj.org/article/0b2bb91e65674e4bbb74c465e11d465a
Autor:
Monica Sathyanesan, Samuel S. Newton
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
A significant body of research has demonstrated that antidepressants regulate neurotrophic factors and that neurotrophins themselves are capable of independently producing antidepressant-like effects. While brain derived neurotrophic factor (BDNF) re
Externí odkaz:
https://doaj.org/article/c5a35d2891f34cc9b4c73d6f2700c63b
Autor:
Avery D. Franzen, Tukiet T. Lam, Kenneth R. Williams, Angus C. Nairn, Ronald S. Duman, Monica Sathyanesan, Vikas Kumar, Linda L. Carpenter, Samuel S. Newton
Publikováno v:
BMC Psychiatry, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background Depression affects approximately 7.1% of the United States population every year and has an annual economic burden of over $210 billion dollars. Several recent studies have sought to investigate the pathophysiology of depression u
Externí odkaz:
https://doaj.org/article/a114c8eade1c4e04a18a234e204ff3ee
Autor:
Samuel S. Newton, Monica Sathyanesan
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Cognitive deficits are widespread in psychiatric disorders, including major depression and schizophrenia. These deficits are known to contribute significantly to the accompanying functional impairment. Progress in the development of targeted treatmen
Externí odkaz:
https://doaj.org/article/4903a4a0106341d4b7796aa1313aa0cc
Publikováno v:
Life, Vol 11, Iss 4, p 359 (2021)
In recent years, erythropoietin (EPO) has emerged as a useful neuroprotective and neurotrophic molecule that produces antidepressant and cognitive-enhancing effects in psychiatric disorders. However, EPO robustly induces erythropoiesis and elevates r
Externí odkaz:
https://doaj.org/article/10fdf6195f834c6eb21dd333601c5c60
Publikováno v:
Neurobiology of Stress, Vol 10, Iss , Pp - (2019)
The two strains of inbred mice, BALB/c and C57BL/6, are widely used in pre-clinical psychiatry research due to their differences in stress susceptibility. Gene profiling studies in these strains have implicated the inflammation pathway as the main co
Externí odkaz:
https://doaj.org/article/609cac17865d4ca187fb04861c39e126
Publikováno v:
Drug Design, Development and Therapy. 14:5393-5403
Introduction Carbamoylated erythropoietin (CEPO) is a chemically engineered, nonhematopoietic derivative of erythropoietin (EPO) that retains its antidepressant and pro-cognitive effects, which are attributed to the increased expression of neurotroph
Publikováno v:
Life, Vol 11, Iss 359, p 359 (2021)
Life
Volume 11
Issue 4
Life
Volume 11
Issue 4
In recent years, erythropoietin (EPO) has emerged as a useful neuroprotective and neurotrophic molecule that produces antidepressant and cognitive-enhancing effects in psychiatric disorders. However, EPO robustly induces erythropoiesis and elevates r