Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Samuel S. Hinman"'
Autor:
Yuli Wang, Raehyun Kim, Samuel S. Hinman, Bailey Zwarycz, Scott T. Magness, Nancy L. Allbritton
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 5, Iss 3, Pp 440-453.e1 (2018)
The relationship between intestinal stem cells (ISCs) and the surrounding niche environment is complex and dynamic. Key factors localized at the base of the crypt are necessary to promote ISC self-renewal and proliferation, to ultimately provide a co
Externí odkaz:
https://doaj.org/article/2942040691604e8896017a199718e22d
Autor:
Samuel S. Hinman, Angelo Massaro, Yuli Wang, Christopher E. Sims, Raehyun Kim, Nancy L. Allbritton
Publikováno v:
Advanced biology. 6(11)
The human colon plays a critical role in fluid and salt absorption and harbors the largest immune compartment. There is a widespread need for in vitro models of human colon physiology with its innate immune system. A method is described to produce a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3a41eb435fb2a9f3047d01a924d56e3
https://pubmed.ncbi.nlm.nih.gov/35773243
https://pubmed.ncbi.nlm.nih.gov/35773243
Autor:
Samuel S. Hinman, Peter J. Attayek, Nancy L. Allbritton, Johanna S. Dutton, Raehyun Kim, Mallory Maurer, Christopher S Sims
Publikováno v:
Integr Biol (Camb)
Hyperglycemia is thought to increase production of inflammatory cytokines and permeability of the large intestine. Resulting intestinal inflammation is then often characterized by excess secretion of tumor necrosis factor alpha (TNFα). Thus, hypergl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fda3509db50bf01743413f27749dd59e
https://doi.org/10.1093/intbio/zyab008
https://doi.org/10.1093/intbio/zyab008
Publikováno v:
Anal Chem
Biochemical gradients across the intestinal epithelium play a major role in governing intestinal stem cell compartmentalization, differentiation dynamics, and organ-level self-renewal. Advances in primary cell-derived in vitro models, in which a full
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffc13c1bcc5eae5388ff29944740fad9
https://doi.org/10.1021/acs.analchem.9b04217
https://doi.org/10.1021/acs.analchem.9b04217
Publikováno v:
Trends Biotechnol
The development of physiologically relevant intestinal models fueled by breakthroughs in primary cell-culture methods has enabled successful recapitulation of key features of intestinal physiology. These advances, paired with engineering methods, for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6a509323b6e8c5be9e82367754435da
https://doi.org/10.1016/j.tibtech.2018.12.001
https://doi.org/10.1016/j.tibtech.2018.12.001
Publikováno v:
Nat Protoc
The large intestine, with its array of crypts lining the epithelium and diverse luminal contents, regulates homeostasis throughout the body. In vitro crypts formed from primary human intestinal epithelial stem cells on a three-dimensional shaped hydr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92874d922970277cafcedb3f88e85394
https://pubmed.ncbi.nlm.nih.gov/33299154
https://pubmed.ncbi.nlm.nih.gov/33299154
Autor:
Nancy L. Allbritton, K. Scott Phillips, Raehyun Kim, Samuel S. Hinman, Peter J. Attayek, Yuli Wang
Publikováno v:
Curr Opin Biomed Eng
Design parameters for microphysiological systems (MPS) are driven by the need for new tools to answer questions focusing on human physiology in a robust and reliable manner. Within this perspective, engineering benchmarks and principles are identifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f27a5ae5dcf4cba15749b1a6bc7250da
https://pubmed.ncbi.nlm.nih.gov/32095672
https://pubmed.ncbi.nlm.nih.gov/32095672
Autor:
Quan Cheng, Yiwen Guan, Xiaoya Hu, Samuel S. Hinman, Yue Cao, Kristy S. McKeating, Juan Li, Zhanjun Yang
Publikováno v:
Biosensors and Bioelectronics. 100:304-311
Dual-functional cupric oxide nanorods (CuONRs) as peroxidase mimics are proposed for the development of a flow-through, label-free chemiluminescent (CL) immunosensor. Forming the basis of this cost-efficient, label-free immunoassay, CuONRs, synthesiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a451b42fcdb54e2eb34c644f856b1957
https://doi.org/10.1016/j.bios.2017.09.011
https://doi.org/10.1016/j.bios.2017.09.011
Autor:
Scott T. Magness, Raehyun Kim, Bailey Zwarycz, Nancy L. Allbritton, Samuel S. Hinman, Yuli Wang
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 5, Iss 3, Pp 440-453.e1 (2018)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
The relationship between intestinal stem cells (ISCs) and the surrounding niche environment is complex and dynamic. Key factors localized at the base of the crypt are necessary to promote ISC self-renewal and proliferation, to ultimately provide a co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aea8c4f8eb2812e2f06ed7ce0ac97cc8
http://www.sciencedirect.com/science/article/pii/S2352345X18300146
http://www.sciencedirect.com/science/article/pii/S2352345X18300146
Publikováno v:
Advanced Healthcare Materials. 10:2101318
The second messenger, intracellular free calcium (Ca2+ ), acts to transduce mitogenic and differentiation signals incoming to the colonic epithelium. A self-renewing monolayer of primary murine colonic epithelial cells is formed over a soft, transpar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8abb3a15f278b89e58e0f2272e9eff1
https://doi.org/10.1002/adhm.202101318
https://doi.org/10.1002/adhm.202101318