Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Samuel Ruiz de Martin Esteban"'
Autor:
Ana M. Fernandez, Laura Martinez-Rachadell, Marta Navarrete, Julia Pose-Utrilla, Jose Carlos Davila, Jaime Pignatelli, Sonia Diaz-Pacheco, Santiago Guerra-Cantera, Emilia Viedma-Moreno, Rocio Palenzuela, Samuel Ruiz de Martin Esteban, Ricardo Mostany, Cristina Garcia-Caceres, Matthias Tschöp, Teresa Iglesias, Maria L. de Ceballos, Antonia Gutierrez, Ignacio Torres Aleman
Publikováno v:
Proc. Natl. Acad. Sci. U.S.A. 119:e2204527119 (2022)
Digital.CSIC. Repositorio Institucional del CSIC
instname
DDFV. Repositorio Institucional de la Universidad Francisco de Vitoria
Digital.CSIC. Repositorio Institucional del CSIC
instname
DDFV. Repositorio Institucional de la Universidad Francisco de Vitoria
Mice with insulin receptor (IR)-deficient astrocytes (GFAP-IR knockout [KO] mice) show blunted responses to insulin and reduced brain glucose uptake, whereas IRdeficient astrocytes show disturbed mitochondrial responses to glucose. While exploring th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::835057f9dc0c75bd197071238b9fc85a
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=67284
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=67284
The Insulin Receptor in Astrocytes is Involved in the Entrance of Circulating Insulin into the Brain
Autor:
Ana M. Fernandez, M. Navarrete, Jose Carlos Davila, Cristina Garcia-Caceres, Rocio Palenzuela, Samuel Ruiz de Martin Esteban, Ricardo Mostany, Matthias Tschöp, Antonia Gutierrez, Ignacio Torres Aleman
Circulating insulin enters into the brain through mechanisms that are not yet entirely understood. We now report that mice lacking insulin receptors (IR) in astrocytes show reduced uptake of circulating insulin and blunted brain responses to this cir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09b555a31ff651df3426197e978d4208
Autor:
Gonzalo Ruiz-Pérez, Samuel Ruiz de Martín Esteban, Sharai Marqués, Noelia Aparicio, M. Teresa Grande, Irene Benito-Cuesta, Ana M. Martínez-Relimpio, M. Andrea Arnanz, Rosa M. Tolón, María Posada-Ayala, Benjamin F. Cravatt, José A. Esteban, Julián Romero, Rocío Palenzuela
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-19 (2021)
Abstract Background The complex pathophysiology of Alzheimer’s disease (AD) hampers the development of effective treatments. Attempts to prevent neurodegeneration in AD have failed so far, highlighting the need for further clarification of the unde
Externí odkaz:
https://doaj.org/article/04889a4e705342f5872aede81d9dbb99
Autor:
Samuel Ruiz de Martín Esteban, Irene Benito-Cuesta, Itziar Terradillos, Ana M. Martínez-Relimpio, M. Andrea Arnanz, Gonzalo Ruiz-Pérez, Claudia Korn, Catarina Raposo, Roman C. Sarott, Matthias V. Westphal, Izaskun Elezgarai, Erick M. Carreira, Cecilia J. Hillard, Uwe Grether, Pedro Grandes, M. Teresa Grande, Julián Romero
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The distribution and roles of the cannabinoid CB2 receptor in the CNS are still a matter of debate. Recent data suggest that, in addition to its presence in microglial cells, the CB2 receptor may be also expressed at low levels, yet biologically rele
Externí odkaz:
https://doaj.org/article/971c3ccb7b28416a96223192611a4cd6