Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Samuel Pena-Díaz"'
Autor:
Samuel Pena-Díaz, Salvador Ventura
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 3, Pp 508-511 (2022)
Parkinson’s disease, the second most prevalent neurodegenerative disorder worldwide, is characterized by a progressive loss of dopaminergic neurons in substantia nigra pars compacta, causing motor symptoms. This disorder’s main hallmark is the fo
Externí odkaz:
https://doaj.org/article/a1d3dd449573489eb7b0d148fb0550e4
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 3, Pp 509-511 (2024)
Externí odkaz:
https://doaj.org/article/e62a20daa9d94a74a0630d61a018c189
Autor:
Jaime Santos, Pablo Gracia, Susanna Navarro, Samuel Peña-Díaz, Jordi Pujols, Nunilo Cremades, Irantzu Pallarès, Salvador Ventura
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
α-Synuclein (αS) aggregation is a driver of several neurodegenerative disorders. Here, the authors identify a class of peptides that bind toxic αS oligomers and amyloid fibrils but not monomeric functional protein, and prevent further αS aggregat
Externí odkaz:
https://doaj.org/article/babb4836107c429db56c82e49b2776a5
Autor:
Serena Vittorio, Ilenia Adornato, Rosaria Gitto, Samuel Peña-Díaz, Salvador Ventura, Laura De Luca
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 1727-1735 (2020)
Parkinson’s disease is one of the most common neurodegenerative disorders in elderly age. One of the mechanisms involved in the neurodegeneration appears related to the aggregation of the presynaptic protein alpha synuclein (α-syn) into toxic olig
Externí odkaz:
https://doaj.org/article/8e22f912610347c8ba292a3ad609a7b1
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 839 (2023)
Parkinson’s disease, the second most common neurodegenerative disorder worldwide, is characterized by the accumulation of protein deposits in the dopaminergic neurons. These deposits are primarily composed of aggregated forms of α-Synuclein (α-Sy
Externí odkaz:
https://doaj.org/article/551dec901af841c685af46318052492d
Autor:
Samuel Peña-Díaz, Jordi Pujols, Francisca Pinheiro, Jaime Santos, Irantzu Pallarés, Susanna Navarro, María Conde-Gimenez, Jesús García, Xavier Salvatella, Esther Dalfó, Javier Sancho, Salvador Ventura
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Synucleinopathies are a group of disorders characterized by the accumulation of α-Synuclein amyloid inclusions in the brain. Preventing α-Synuclein aggregation is challenging because of the disordered nature of the protein and the stochastic nature
Externí odkaz:
https://doaj.org/article/83c408dfd2af40d4873f844dcb3eb62c
Publikováno v:
Neural Regeneration Research, Vol 15, Iss 12, Pp 2260-2261 (2020)
Externí odkaz:
https://doaj.org/article/b04b3d2c297f469d8ba05192d8dda935
Autor:
Samuel Peña-Díaz, Jordi Pujols, María Conde-Giménez, Anita Čarija, Esther Dalfo, Jesús García, Susanna Navarro, Francisca Pinheiro, Jaime Santos, Xavier Salvatella, Javier Sancho, Salvador Ventura
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
α-Synuclein (α-Syn) forms toxic intracellular protein inclusions and transmissible amyloid structures in Parkinson’s disease (PD). Preventing α-Syn self-assembly has become one of the most promising approaches in the search for disease-modifying
Externí odkaz:
https://doaj.org/article/271de745d09441ae8c687f01fdd96906