Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Samuel OW"'
Autor:
Jia Li Low, Elaine Lim, Lavina Bharwani, Andrea Wong, Karmen Wong, Samuel Ow, Siew Eng Lim, Matilda Lee, Joan Choo, Joline Lim, Gloria Chan, Robert John Walsh, Vaishnavi Muthu, Natalie Ngoi, Wanqin Chong, Sing Huang Tan, Soo Chin Lee
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 14 (2022)
Background: Oestrogen receptor positive, human epidermal growth factor receptor-2 (HER2) negative breast cancer (BC) is the most frequently diagnosed BC subtype. Combinations of cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) with anti-oestrogen the
Externí odkaz:
https://doaj.org/article/e7fedfe987e74365b96a9e8c0c6b25b7
Autor:
Kay Reen Ting, Pei Yi Ong, Samuel Ow Guan Wei, Rajeev Parameswaran, Chin Meng Khoo, Doddabele Srinivasa Deepak, Soo-Chin Lee
Publikováno v:
Hereditary Cancer in Clinical Practice, Vol 18, Iss 1, Pp 1-11 (2020)
Abstract Background Hereditary paraganglioma (PGL) and pheochromocytoma (PCC) syndromes are rare conditions, with limited data on spectrum of causative gene variants of these syndromes in Asian patients. Methods We describe the clinical characteristi
Externí odkaz:
https://doaj.org/article/cb7eba1770604ae8ac290da41d9c73a5
Autor:
Ravindran Kanesvaran, Puey Ling Chia, Edmund Chiong, Melvin Lee Kiang Chua, Nye Thane Ngo, Samuel Ow, Hong Gee Sim, Min-Han Tan, Kiang Hiong Tay, Alvin Seng Cheong Wong, Siew Wei Wong, Puay Hoon Tan
Publikováno v:
Annals of the Academy of Medicine, Singapore. 52:135-148
Introduction: There has been a rapid evolution in the treatment strategies for metastatic castration-resistant prostate cancer (mCRPC) following the identification of targetable mutations, making genetic testing essential for patient selection. Altho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7c7fd77ec7e74e7d93f17ad5e7ae184
https://doi.org/10.47102/annals-acadmedsg.2022372
https://doi.org/10.47102/annals-acadmedsg.2022372
Autor:
Courage Edem Ketor, Juliet McDonnell, Charles Kwaku Benneh, Emmanuel Sarkodie, Isaac Annobil, Fidelis Atia, Adelaide Mensah, Samuel Owusu Somuah, Selorm Akakpo
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background The Ghana Health Service aims to ensure the health of all Ghanaians. Understanding the factors that influence people’s health-seeking behaviour will help the Ghana Health Service evaluate and enact policies that will enable it t
Externí odkaz:
https://doaj.org/article/ed497009dfc2428b8ab9b42955d20d68
A novel translational model of atherosclerosis, the ex vivo pump-perfused amputated human limb model
Autor:
Adam Hartley, Jonathan Afoke, Guiqing Liu, Samuel Owen, Reza Hajhosseiny, Kimberly Hassen, Prakash Punjabi, Dorian Haskard, Joseph Shalhoub, Ramzi Khamis
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The preclinical study of atherosclerosis has traditionally centred around the use of small animal models, translating to large animal models, prior to first-in-man studies. We propose to disrupt this paradigm by designing an ex vivo pump per
Externí odkaz:
https://doaj.org/article/a21a5569c1134a95a7c1d0b93def871c
Autor:
Gerheart Winfred Ashong, Boansi Adu Ababio, Edward Ebow Kwaansa-Ansah, Enock Gyabeng, Samuel Owusu Nti
Publikováno v:
Toxicology Reports, Vol 12, Iss , Pp 404-413 (2024)
The disposal of polymer post-treatment sludge (PTS) from Barekese Water Treatment Plants (WTPs) as organic fertilizer and aquatic feed is a common practice in Ghana, necessitating a thorough evaluation of its ecological and human health risks. This s
Externí odkaz:
https://doaj.org/article/e9303eb370e342b9997d4904c59a5971
Autor:
Matilda Xinwei Lee, Andrea L. A. Wong, Samuel Ow, Raghav Sundar, David S. P. Tan, Ross A. Soo, Cheng Ean Chee, Joline S. J. Lim, Wei Peng Yong, Siew Eng Lim, Boon Cher Goh, Lingzhi Wang, Soo Chin Lee
Publikováno v:
Targeted oncology. 17(2)
Varlitinib is a highly potent, small-molecule, pan-HER inhibitor targeting HER1, HER2, and HER4. It has demonstrated activity in gastric, biliary tract, and breast cancers.We conducted a phase Ib dose confirmation study to determine safety and early
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47e60cc090a077974fbe6f3446f7049f
https://pubmed.ncbi.nlm.nih.gov/35195837
https://pubmed.ncbi.nlm.nih.gov/35195837
Autor:
Ming-Shen Dai, Yin Hsun Feng, Shang Wen Chen, Norikazu Masuda, Chung Cheung Thomas Yau, Shou Tung Chen, Yen Shen Lu, Yoon Sim Yap, Peter Cher Siang Ang, Sung Chao Chu, Ava Kwong, Keun Seok Lee, Samuel Ow, Sung Bae Kim, Johnson Lin, Hyun Cheol Chung, Roger Ngan, Victor C. Kok, Kun Ming Rau, Takafumi Sangai, Ting Ying Ng, Ling Ming Tseng, Richard Bryce, Kiana Keyvanjah, Judith Bebchuk, Mei Chieh Chen, Ming-Feng Hou
Purpose: Neratinib, an irreversible pan-HER tyrosine kinase inhibitor, has demonstrated systemic efficacy and intracranial activity in various stages of HER2+ breast cancer. NALA was a phase III randomized trial that assessed the efficacy and safety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::981e0a30098eb7c9a7ed1bc47ef2cf3d
https://doi.org/10.21203/rs.3.rs-404446/v1
https://doi.org/10.21203/rs.3.rs-404446/v1
Autor:
Takafumi Sangai, Thomas Yau, Yen-Shen Lu, Kun Ming Rau, Ting Ying Ng, Ming-Shen Dai, Roger K.C. Ngan, Johnson Lin, Ming-Feng Hou, Sung-Bae Kim, Peter Ang, Ava Kwong, Mei Chieh Chen, Shang Wen Chen, Norikazu Masuda, Richard A. Bryce, Sung Chao Chu, Hyun Cheol Chung, Samuel Ow, Judith Bebchuk, Yin Hsun Feng, Yoon Sim Yap, Keun Seok Lee, Ling Ming Tseng, Victor C. Kok, Shou Tung Chen
Publikováno v:
Breast Cancer Research and Treatment
Purpose Neratinib, an irreversible pan-HER tyrosine kinase inhibitor, has demonstrated systemic efficacy and intracranial activity in various stages of HER2+breast cancer. NALA was a phase III randomized trial that assessed the efficacy and safety of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4478f4b9a2bc4209d4e29babb70294a3
https://pubmed.ncbi.nlm.nih.gov/34553296
https://pubmed.ncbi.nlm.nih.gov/34553296
Autor:
Soo-Chin Lee, Kay Reen Ting, Samuel Ow Guan Wei, Doddabele Srinivasa Deepak, Pei Yi Ong, Chin Meng Khoo, Rajeev Parameswaran
Publikováno v:
Hereditary Cancer in Clinical Practice
Hereditary Cancer in Clinical Practice, Vol 18, Iss 1, Pp 1-11 (2020)
Hereditary Cancer in Clinical Practice, Vol 18, Iss 1, Pp 1-11 (2020)
Background Hereditary paraganglioma (PGL) and pheochromocytoma (PCC) syndromes are rare conditions, with limited data on spectrum of causative gene variants of these syndromes in Asian patients. Methods We describe the clinical characteristics and ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89f152329489b0c10af2c8131157d19d
https://doi.org/10.1186/s13053-020-00156-9
https://doi.org/10.1186/s13053-020-00156-9