Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Samuel O Pine"'
Autor:
Natasha Dubois Cauwelaert, Anthony L Desbien, Thomas E Hudson, Samuel O Pine, Steven G Reed, Rhea N Coler, Mark T Orr
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146372 (2016)
The Toll-like receptor 4 agonist glucopyranosyl lipid adjuvant formulated in a stable emulsion (GLA-SE) promotes strong TH1 and balanced IgG1/IgG2 responses to protein vaccine antigens. This enhanced immunity is sufficient to provide protection again
Externí odkaz:
https://doaj.org/article/9f915c23edb44b2d9941d80c3a0e1d95
Autor:
Samuel O Pine, James G Kublin, Scott M Hammer, Joleen Borgerding, Yunda Huang, Danilo R Casimiro, M Juliana McElrath
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18526 (2011)
The results of the recent Step Study highlight a need to clarify the effects of pre-existing natural immunity to a vaccine vector on vaccine-induced T-cell responses. To investigate this interaction, we examined the relationship between pre-existing
Externí odkaz:
https://doaj.org/article/01ea84be10164d5fbaab8fb7118ddb29
Autor:
Swati Gupta, Sylvie Bertholet, Daniela Verthelyi, Jason Delcarpini, George R Gunn, Richard Siggers, Anna Ma, Fabio Garofolo, Lisa Kierstead, Mark Milton, Francis Dessy, Johann Poetzl, Arno Kromminga, Boris Gorovits, Marco Petrillo, Madeleine Dahlbäck, Lynne Jesaitis, Robert J Kubiak, Becky Schweighardt, Mohsen Rajabi Abhari, Kay Stubenrauch, Meina Liang, Yanmei Lu, Susan Kirshner, Haoheng Yan, John Kamerud, Rocio Murphy, Naveen Dakappagari, Holger Koch, Akiko Ishii-Watabe, Yuanxin Xu, Sam Song, Michael A Partridge, Lucia Zhang, Chris Stebbins, Vibha Jawa, Andrew Exley, Elana Cherry, Jim McNally, Manoj Rajadhyaksha, Bart Corsaro, Bonnie Wu, Therese Solstad, Jean-Claude Marshall, Isabelle Cludts, Ivo Sonderegger, Sumit Kar, Tong-Yuan Yang, Roland F Staack, João Pedras-Vasconcelos, Natasha Savoie, Yuling Wu, Samuel O. Pine, Ghanashyam Sarikonda
Publikováno v:
Bioanalysis. 13:415-463
The 14th edition of the Workshop on Recent Issues in Bioanalysis (14th WRIB) was held virtually on June 15-29, 2020 with an attendance of over 1000 representatives from pharmaceutical/biopharmaceutical companies, biotechnology companies, contract res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78dad76399423931f3bb96a1903bd264
https://doi.org/10.4155/bio-2021-0007
https://doi.org/10.4155/bio-2021-0007
Autor:
Anne S. De Groot, Sophie Tourdot, Gregor P Lotz, Nikki Dellas, Arno Kromminga, Luca Piccoli, Carolina B Quaglia, Susan M. Richards, Günter Waxenecker, Eric Guillemare, Federico Mingozzi, Samuel O. Pine, Paul Chamberlain, Daniel Kramer
Publikováno v:
Bioanalysis. 12:1043-1048
Given the expanding number of complex therapeutic protein drugs and advanced therapy medicinal products that are being developed, improving our ability to assess the potential immunogenicity of biologics is critical to ensuring treatment efficacy and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dd5ecdcdd60ae786fc79bc551b2df8d
https://doi.org/10.4155/bio-2020-0150
https://doi.org/10.4155/bio-2020-0150
Autor:
Samuel O. Pine, Eric Woolf, Jeb Adams, Ryan Kelly, Jason Kentner, Michelle L. Dawes, Joel Usansky, Kimberly Honrine, John F. Kellie, Scott Davis, Shibani Mitra-Kaushik, John Evens, Hannes Hochreiner, Sean M. Crawford
Publikováno v:
Bioanalysis. 13(17)
Challenges for data storage during drug development have become increasingly complex as the pharmaceutical industry expands in an environment that requires on-demand availability of data and resources for users across the globe. While the efficiency
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99a6803fff65a83d92d507d84c7b4bcf
https://pubmed.ncbi.nlm.nih.gov/34515519
https://pubmed.ncbi.nlm.nih.gov/34515519
Autor:
Bart, Corsaro, Tong-Yuan, Yang, Rocio, Murphy, Ivo, Sonderegger, Andrew, Exley, Sylvie, Bertholet, Naveen, Dakappagari, Francis, Dessy, Fabio, Garofolo, Lisa, Kierstead, Holger, Koch, Ghanashyam, Sarikonda, Natasha, Savoie, Richard, Siggers, Therese, Solstad, Yanmei, Lu, Mark, Milton, Jean-Claude, Marshall, Jason, DelCarpini, Boris, Gorovits, Swati, Gupta, Lynne, Jesaitis, John, Kamerud, Arno, Kromminga, Anna, Ma, Jim, McNally, Haoheng, Yan, Bonnie, Wu, Daniela, Verthelyi, Susan, Kirshner, Joao, Pedras-Vasconcelos, Manoj, Rajadhyaksha, Roland F, Staack, Elana, Cherry, Isabelle, Cludts, Madeleine, Dahlbäck, George R, Gunn, Akiko, Ishii-Watabe, Vibha, Jawa, Robert, Kubiak, Michael, Partridge, Marco, Petrillo, Samuel O, Pine, Johann, Poetzl, Sam, Song, Chris, Stebbins, Yuling, Wu, Lucia, Zhang, Sumit, Kar, Meina, Liang, Mohsen Rajabi, Abhari, Becky, Schweighardt, Kay, Stubenrauch, Yuanxin, Xu
Publikováno v:
Bioanalysis. 13(6)
The 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::40e211e9d228d8f55e8aa54ba0385b30
https://pubmed.ncbi.nlm.nih.gov/33533276
https://pubmed.ncbi.nlm.nih.gov/33533276
Publikováno v:
Journal of Immunological Methods. 487:112896
Detection of anti-drug antibodies (ADA) that have a neutralizing capacity is an important aspect of immunogenicity evaluation during development of biotherapeutics, but developing and validating neutralizing antibody (NAb) assays that show direct int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfad33b5cb78ce5177fcedf310ae3cd0
https://doi.org/10.1016/j.jim.2020.112896
https://doi.org/10.1016/j.jim.2020.112896
Autor:
Anna Marie Beckmann, Stuart J. Kahn, Karen D. Cowgill, Edva P. Vieira, Evaldo Nascimento, Demetrios F. Fernandes, Samuel O. Pine, Rhea N. Coler, Franco M. Piazza, Lisa Y. Bogatzki, Jill A. Ashman, Antonio Campos-Neto, Fabiana P. Alves, Steven G. Reed
Publikováno v:
Vaccine. 28:6581-6587
Forty-four adult patients with cutaneous leishmaniasis (CL) were enrolled in a randomized, double-blind, controlled, dose-escalating clinical trial and were randomly assigned to receive three injections of either the LEISH-F1 + MPL-SE vaccine (consis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b564f7439a7497b97b5bd4632c6fe7ea
https://doi.org/10.1016/j.vaccine.2010.07.063
https://doi.org/10.1016/j.vaccine.2010.07.063
Publikováno v:
AIDS, vol. 23, no. 18, pp. 2387-2395
OBJECTIVES: Toll-like receptors (TLRs) are innate immune sensors that are integral to resisting chronic and opportunistic infections. Mounting evidence implicates TLR polymorphisms in susceptibilities to various infectious diseases, including HIV-1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71d1ffadbaac2220f9686d07ab3b27c7
https://doi.org/10.1097/qad.0b013e328330b489
https://doi.org/10.1097/qad.0b013e328330b489
Autor:
Mark T. Orr, Magdalini Moutaftsi, Aarthy C. Vallur, Samuel O. Pine, Steven G. Reed, Susan L. Baldwin, Sylvie Bertholet, Elyse Lucas, Lance K. Ching, Rhea N. Coler
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 191(5)
Considerable effort has been directed to develop Mycobacterium tuberculosis vaccines to boost bacille Calmette-Guérin or for those who cannot be immunized with bacille Calmette-Guérin. We hypothesized that CD4+ and CD8+ T cell responses with a hete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21c1e15418605e56cf0566120df9c82d
https://pubmed.ncbi.nlm.nih.gov/23904160
https://pubmed.ncbi.nlm.nih.gov/23904160