Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Samuel Montcalm"'
Autor:
Kristy Favell, Christopher B. Kent, Rhalena A. Thomas, Kathleen Daignault, Melissa A. Wright, Gino B. Ferraro, Alyson E. Fournier, Jordi Pérez-Tur, Madeline Pool, Yves Durocher, Philip A. Barker, Samuel Montcalm, José Manuel Morante-Redolat
Publikováno v:
The Journal of Neuroscience. 30:6607-6612
Mutations in leucine-rich glioma inactivated (LGI1) are a genetic cause of autosomal dominant temporal lobe epilepsy with auditory features. LGI1 is a secreted protein that shares homology with members of the SLIT family, ligands that direct axonal r
Autor:
Alyson E. Fournier, Samuel Montcalm, Mohammad R. Khazaei, Stephan Ong Tone, Adriana Di Polo, Yves Durocher
Publikováno v:
Journal of molecular neuroscience : MN. 55(2)
Neurons fail to re-extend their processes within the central nervous system environment in vivo, and this is partly because of inhibitory proteins expressed within myelin debris and reactive astrocytes that actively signal to the injured nerve cells
Autor:
Zuomei Li, Alain Ajamian, Sukhdev Manku, Silvana Leit, Marielle Fournel, Martin Allan, Jeffrey M. Besterman, Yves Andre Chantigny, Amal Wahhab, Eric Therrien, Theresa P. Yan, Sylvain Lefebvre, Jubrail Rahil, Andrea J. Petschner, Alina Nicolescu, David Smil, Robert Deziel, Aihua Lu, Samuel Montcalm, Natalie Nguyen
Publikováno v:
Bioorganicmedicinal chemistry letters. 19(2)
The sulfamide moiety has been utilized to design novel HDAC inhibitors. The potency and selectivity of these inhibitors were influenced both by the nature of the scaffold, and the capping group. Linear long-chain-based analogs were primarily HDAC6-se