Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Samuel Miravet-Verde"'
Autor:
Miquel Anglada-Girotto, Ludovica Ciampi, Sophie Bonnal, Sarah A. Head, Samuel Miravet-Verde, Luis Serrano
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Alternative splicing is crucial for cancer progression and can be targeted pharmacologically, yet identifying driver exons genome-wide remains challenging. We propose identifying such exons by associating statistically gene-level cancer depe
Externí odkaz:
https://doaj.org/article/47cd56bdd35f4ce69a02ba166469da0f
Autor:
Samuel Miravet-Verde, Rocco Mazzolini, Carolina Segura-Morales, Alicia Broto, Maria Lluch-Senar, Luis Serrano
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Identifying open reading frames (ORFs) being translated is not a trivial task. ProTInSeq is a technique designed to characterize proteomes by sequencing transposon insertions engineered to express a selection marker when they occur in-frame
Externí odkaz:
https://doaj.org/article/4737d8ad11ee4bcea5a868ec42cd75f1
Autor:
Samuel Miravet-Verde, Rocco Mazzolini, Carolina Segura-Morales, Alicia Broto, Maria Lluch-Senar, Luis Serrano
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/9acad02bbe4e4edaa1de285c4c5178bf
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-9 (2022)
Abstract Background Independent Component Analysis (ICA) allows the dissection of omic datasets into modules that help to interpret global molecular signatures. The inherent randomness of this algorithm can be overcome by clustering many iterations o
Externí odkaz:
https://doaj.org/article/84befb490a774110805f0c0b715aabc2
Autor:
Alicia Broto, Erika Gaspari, Samuel Miravet-Verde, Vitor A. P. Martins dos Santos, Mark Isalan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Mycoplasmas are minimal cell model organisms but lack genetic tools. Here the authors provide a robust genetic toolkit for Mycoplasma demonstrating gene circuit engineering applications.
Externí odkaz:
https://doaj.org/article/c48ffcf56ee64f81b6a8d4c02e5ebac5
Publikováno v:
Microbial Biotechnology, Vol 14, Iss 6, Pp 2403-2419 (2021)
Summary The removal of unwanted genetic material is a key aspect in many synthetic biology efforts and often requires preliminary knowledge of which genomic regions are dispensable. Typically, these efforts are guided by transposon mutagenesis studie
Externí odkaz:
https://doaj.org/article/37be770e951f4fe5b809c00854c92a1a
Autor:
Ana Martín-Pardillos, Ángeles Valls Chiva, Gemma Bande Vargas, Pablo Hurtado Blanco, Roberto Piñeiro Cid, Pedro J. Guijarro, Stefan Hümmer, Eva Bejar Serrano, Aitor Rodriguez-Casanova, Ángel Diaz-Lagares, Josep Castellvi, Samuel Miravet-Verde, Luis Serrano, María Lluch-Senar, Víctor Sebastian, Ana Bribian, Laura López-Mascaraque, Rafael López-López, Santiago Ramón y Cajal
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-26 (2019)
Abstract Background Cancer is a rapidly evolving, multifactorial disease that accumulates numerous genetic and epigenetic alterations. This results in molecular and phenotypic heterogeneity within the tumor, the complexity of which is further amplifi
Externí odkaz:
https://doaj.org/article/ae4d1b255d0540ae8d2c501bbcc4b97b
Autor:
Ariadna Montero-Blay, Carlos Piñero-Lambea, Samuel Miravet-Verde, Maria Lluch-Senar, Luis Serrano
Publikováno v:
Cell Reports, Vol 31, Iss 9, Pp - (2020)
Summary: Here, we propose an approach to identify active metabolic pathways by integrating gene essentiality analysis and protein abundance. We use two bacterial species (Mycoplasma pneumoniae and Mycoplasma agalactiae) that share a high gene content
Externí odkaz:
https://doaj.org/article/7c2f43429beb46dd8fdb8db1d1f74c0b
Autor:
Samuel Miravet‐Verde, Tony Ferrar, Guadalupe Espadas‐García, Rocco Mazzolini, Anas Gharrab, Eduard Sabido, Luis Serrano, Maria Lluch‐Senar
Publikováno v:
Molecular Systems Biology, Vol 15, Iss 2, Pp n/a-n/a (2019)
Abstract Identification of small open reading frames (smORFs) encoding small proteins (≤ 100 amino acids; SEPs) is a challenge in the fields of genome annotation and protein discovery. Here, by combining a novel bioinformatics tool (RanSEPs) with
Externí odkaz:
https://doaj.org/article/1d0bc80f694d49b2a6fc9d864463ce06
Autor:
Ludovica, Ciampi, Federica, Mantica, Laura, López-Blanch, Jon, Permanyer, Cristina, Rodriguez-Marín, Jingjing, Zang, Damiano, Cianferoni, Senda, Jiménez-Delgado, Sophie, Bonnal, Samuel, Miravet-Verde, Verena, Ruprecht, Stephan C F, Neuhauss, Sandro, Banfi, Sabrina, Carrella, Luis, Serrano, Sarah A, Head, Manuel, Irimia
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(29)
Retinal photoreceptors have a distinct transcriptomic profile compared to other neuronal subtypes, likely reflecting their unique cellular morphology and function in the detection of light stimuli by way of the ciliary outer segment. We discovered a