Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Samuel McGee"'
Autor:
Huiping Shi, Bojing Shao, Liang Gao, Thamizhiniyan Venkatesan, John Michael McDaniel, Meixiang Zhou, Samuel McGee, Pengchun Yu, Jasimuddin Ahamed, Janna Journeycake, James N. George, Lijun Xia
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(34)
Vaso-occlusive episode (VOE) is a common and critical complication of sickle cell disease (SCD). Its pathogenesis is incompletely understood. von Willebrand factor (VWF), a multimeric plasma hemostatic protein synthesized and secreted by endothelial
Autor:
Yizhi Jiang, Lijun Xia, Yaqiong Tang, Changgeng Ruan, Jamey D. Marth, Bojing Shao, Yue Han, Florea Lupu, Depei Wu, J. Michael McDaniel, Robert Silasi-Mansat, Meixiang Zhou, Damien Restagno, Xia Bai, Liang Gao, Samuel McGee, Yuji Kondo, Christopher Hoover, Miao Jiang, Dongping Huang
Publikováno v:
Cell Death and Differentiation
The liver has recently been identified as a major organ for destruction of desialylated platelets. However, the underlying mechanism remains unclear. Kupffer cells, which are professional phagocytic cells in the liver, comprise the largest population
Autor:
Venu Lagishetty, Lijun Xia, Courtney W. Houchen, Justin L. Sonnenburg, Timothy M. Griffin, Liang Gao, David Casero, Negin Kazemian, Rodger P. McEver, J. Michael McDaniel, Bojing Shao, Sepideh Pakpour, Samuel McGee, Jonathan Braun, Chinthalapally V. Rao, Kirk Bergstrom, Christopher M. Hoover, Wesley F. Zandberg, Jonathan P. Jacobs, Albert Batushansky, Xindi Shan, Yuji Kondo, Benjamin Noyovitz, Deanna L. Gibson
Publikováno v:
Science (New York, N.Y.), vol 370, iss 6515
Science
Science
So much more to mucus Mammals accommodate a dense community of metabolically active microorganisms in their gut. This is not a passive relationship, and host and microbe have antagonistic as well as mutualistic responses to each other. Using a whole-
Autor:
Bojing Shao, Christopher Hoover, Huiping Shi, Yuji Kondo, Robert H. Lee, Junmei Chen, Xindi Shan, Jianhua Song, J. Michael McDaniel, Meixiang Zhou, Samuel McGee, Karen Vanhoorelbeke, Wolfgang Bergmeier, José A. López, James N. George, Lijun Xia
Publikováno v:
Blood. 139(16)
Microvascular thrombosis in patients with thrombotic thrombocytopenic purpura (TTP) is initiated by GPIbα-mediated platelet binding to von Willebrand factor (VWF). Binding of VWF to GPIbα causes activation of the platelet surface integrin αIIbβ3.
Autor:
Lijun Xia, Yuji Kondo, Christopher Hoover, Wolfgang Bergmeier, Rodger P. McEver, Samuel McGee, Michael McDaniel, Sidney W. Whiteheart, Robert H. Lee, Bojing Shao
Publikováno v:
Blood. 137(20)
During early embryonic development in mammals, including humans and mice, megakaryocytes (Mks) first originate from primitive hematopoiesis in the yolk sac. These embryonic Mks (eMks) circulate in the vasculature with unclear function. Herein, we rep
Autor:
Harini Bagavant, Yuji Kondo, Kai Song, Florea Lupu, Robert Silasi-Mansat, Brett H. Herzog, Hong Chen, Jianhua Song, J. Michael McDaniel, Jianxin Fu, Lijun Xia, Samuel McGee, Kirk Bergstrom
Publikováno v:
Journal of Biological Chemistry. 292:16491-16497
The kidney's filtration activity is essential for removing toxins and waste products from the body. The vascular endothelial cells of the glomerulus are fenestrated, flattened, and surrounded by podocytes, specialized cells that support glomerular en
Autor:
Divya Vatsa, Samuel McGee, Emily Wood, Christopher J. Smith, B. Blair Braden, Leslie C. Baxter, Amiee Thompson, Tyler K. Glaspy, Angela E. Abbott
Publikováno v:
Autism Research. 10:1945-1959
There is a rapidly growing group of aging adults with autism spectrum disorder (ASD) who may have unique needs, yet cognitive and brain function in older adults with ASD is understudied. We combined functional and structural neuroimaging and neuropsy
Autor:
Rodger P. McEver, Zhenghui Liu, Changgeng Ruan, Roberto Sonon, Jamey D. Marth, Samuel McGee, Yuji Kondo, Jianxin Fu, J. Michael McDaniel, Yannan Qin, Yun Li, Tadayuki Yago, Yun Ling, Christopher Hoover, Parastoo Azadi, Xia Bai, Bojing Shao, Jianhua Song, Lijun Xia
Publikováno v:
Proceedings of the National Academy of Sciences. 114:8360-8365
Most platelet membrane proteins are modified by mucin-type core 1-derived glycans (O-glycans). However, the biological importance of O-glycans in platelet clearance is unclear. Here, we generated mice with a hematopoietic cell-specific loss of O-glyc
Autor:
Leland S. Hu, Laura C. Bell, Ashley M. Stokes, Leslie C. Baxter, Samuel McGee, C. Chad Quarles
Publikováno v:
Tomography
Volume 3
Issue 2
Pages 89-95
Tomography : a journal for imaging research
Tomography; Volume 3; Issue 2; Pages: 89-95
Volume 3
Issue 2
Pages 89-95
Tomography : a journal for imaging research
Tomography; Volume 3; Issue 2; Pages: 89-95
With DSC-MRI, contrast agent leakage effects in brain tumors can either be leveraged for percent signal recovery (PSR) measurements or be adequately resolved for accurate relative cerebral blood volume (rCBV) measurements. Leakage effects can be dimi
Autor:
Fei Liu, Xindi Shan, Kirk Bergstrom, Jianxin Fu, Weichang Chen, Xia Bai, Lijun Xia, J. Michael McDaniel, Samuel McGee
Publikováno v:
The Journal of Experimental Medicine
Mucin-type O-glycans (O-glycans) are a major component of gastric mucus with an unclear function. Liu et al. reports that O-glycans protect gastric mucosa from inflammation and cancer mediated by activation of caspases 1 and 11–dependent inflammaso