Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Samuel Martin-Fonseca"'
Autor:
Antonio Martínez, Andrés García-Granados, Rosa M. Ferrer-Martín, Andrés Parra, Samuel Martin-Fonseca, Fernando J. Reyes-Zurita, José A. Lupiáñez, Francisco Rivas, Marta Medina-O'Donnell
Publikováno v:
European Journal of Medicinal Chemistry. 118:64-78
Several PEGylated derivatives of oleanolic and maslinic acids have been semi-synthesized, attaching one acid-PEG reagent to the hydroxyl group/s at C-2 or C-2/C-3 of the A rings of these natural triterpenes, and also to their corresponding C-28 benzy
Autor:
Marta Medina-O'Donnell, Amalia Pérez-Jiménez, Eva E. Rufino-Palomares, Fernando J. Reyes-Zurita, Juan Peragón, Rosa M. Ferrer-Martín, Samuel Martin-Fonseca, Andrés Parra, José A. Lupiáñez, Francisco Rivas, Andrés García-Granados, Khalida Mokhtari, Pedro P. Medina, Leticia García-Salguero, Antonio Martínez
Publikováno v:
Digibug. Repositorio Institucional de la Universidad de Granada
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Oleanolic acid (1) is a pentacyclic triterpene present in olive pomace, which is known to induce apoptosis and to have anti-tumor properties; however, high concentrations of this product are necessary to produce cytotoxic effects. The 3-O-succinyl-28
Autor:
Fernando Albericio, Antonio Martínez, Francisco Rivas, Andrés García-Granados, Eva E. Rufino-Palomares, Fernando J. Reyes-Zurita, Andrés Parra, José A. Lupiáñez, Marta Medina-O'Donnell, Samuel Martin-Fonseca
Publikováno v:
ACS Combinatorial Science. 16:428-447
A wide set of 264 compounds has been semisynthesized with high yields and purities. These compounds have been obtained through easy synthetic processes based on a solid-phase combinatorial methodology. All the members of this library have one central