Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Samuel Maiser"'
Autor:
Michael Benatar, Eric A. Macklin, Andrea Malaspina, Mary-Louise Rogers, Eran Hornstein, Vittoria Lombardi, Danielle Renfrey, Stephanie Shepheard, Iddo Magen, Yahel Cohen, Volkan Granit, Jeffrey M. Statland, Jeannine M. Heckmann, Rosa Rademakers, Caroline A. McHutchison, Leonard Petrucelli, Corey T. McMillan, Joanne Wuu, Lauren Elman, John Ravits, Jonathan Katz, Jaya Trivedi, Andrea Swenson, Ted M. Burns, James Caress, Carlayne Jackson, Samuel Maiser, Erik P. Pioro, Yuen So
Publikováno v:
EBioMedicine, Vol 108, Iss , Pp 105323- (2024)
Summary: Background: With increasing recognition of the value of incorporating prognostic markers into amyotrophic lateral sclerosis (ALS) trial design and analysis plans, there is a pressing need to understand which among the prevailing clinical and
Externí odkaz:
https://doaj.org/article/e1d4a293db1a412aa52ac92f571d2d19
Autor:
Monica M. Diaz, Xin Hu, Brenda T. Fenton, Ivan Kimuli, Allison Lee, Hayley Lindsey, Jeffrey K. Bigelow, Samuel Maiser, Hamada H. Altalib, Jason J. Sico
Publikováno v:
BMC Neurology, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background While the burden of neurologic illness in developing countries is increasing, less is known about mortality among patients admitted to sub-Saharan African hospitals with neurologic disease. We sought to characterize the rate and p
Externí odkaz:
https://doaj.org/article/9428f7590e5d414889f9923a3531fff2
Autor:
Katerina Placek, Michael Benatar, Joanne Wuu, Evadnie Rampersaud, Laura Hennessy, Vivianna M Van Deerlin, Murray Grossman, David J Irwin, Lauren Elman, Leo McCluskey, Colin Quinn, Volkan Granit, Jeffrey M Statland, Ted M Burns, John Ravits, Andrea Swenson, Jon Katz, Erik P Pioro, Carlayne Jackson, James Caress, Yuen So, Samuel Maiser, David Walk, Edward B Lee, John Q Trojanowski, Philip Cook, James Gee, Jin Sha, Adam C Naj, Rosa Rademakers, The CReATe Consortium, Wenan Chen, Gang Wu, J Paul Taylor, Corey T McMillan
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 1, Pp n/a-n/a (2021)
Abstract Amyotrophic lateral sclerosis (ALS) is a multi‐system disease characterized primarily by progressive muscle weakness. Cognitive dysfunction is commonly observed in patients; however, factors influencing risk for cognitive dysfunction remai
Externí odkaz:
https://doaj.org/article/c97ccf4df05c438e987a0ef12c4302e4
Publikováno v:
MedEdPORTAL, Vol 15 (2019)
Introduction Acute neuromuscular respiratory failure is a source of morbidity and mortality in neurological diseases, including acute inflammatory demyelinating polyneuropathy (AIDP), also known as Guillain-Barré syndrome. It is important for health
Externí odkaz:
https://doaj.org/article/de1b470ae0d945f999bb6f65579acfcc
Autor:
Sabrina Paganoni, Suzanne Hendrix, Samuel P Dickson, Newman Knowlton, James D Berry, Michael A Elliott, Samuel Maiser, Chafic Karam, James B Caress, Margaret Ayo Owegi, Adam Quick, James Wymer, Stephen A Goutman, Daragh Heitzman, Terry D Heiman-Patterson, Carlayne Jackson, Colin Quinn, Jeffrey D Rothstein, Edward J Kasarskis, Jonathan Katz, Liberty Jenkins, Shafeeq S Ladha, Timothy M Miller, Stephen N Scelsa, Tuan H Vu, Christina Fournier, Kristin M Johnson, Andrea Swenson, Namita Goyal, Gary L Pattee, Suma Babu, Marianne Chase, Derek Dagostino, Meghan Hall, Gale Kittle, Mathew Eydinov, Joseph Ostrow, Lindsay Pothier, Rebecca Randall, Jeremy M Shefner, Alexander V Sherman, Eric Tustison, Prasha Vigneswaran, Hong Yu, Joshua Cohen, Justin Klee, Rudolph Tanzi, Walter Gilbert, Patrick Yeramian, Merit Cudkowicz
Publikováno v:
Journal of neurology, neurosurgery, and psychiatry, vol 93, iss 8
BackgroundCoformulated sodium phenylbutyrate/taurursodiol (PB/TURSO) was shown to prolong survival and slow functional decline in amyotrophic lateral sclerosis (ALS).ObjectiveDetermine whether PB/TURSO prolonged tracheostomy/ventilation-free survival
Autor:
Meghan Hall, Janet P. Wittes, Gary L. Pattee, Eric A. Macklin, Eric Tustison, Tuan Vu, Zi-Fan Yu, Samuel P. Dickson, Rudolph E. Tanzi, Liberty Jenkins, Suma Babu, Michael A. Elliott, Jonathan S. Katz, Chafic Karam, Patricia L. Andres, Terry Heiman-Patterson, Stephen N. Scelsa, Christina Fournier, Joseph Ostrow, Timothy M. Miller, Joshua N Cohen, Daragh Heitzman, Edward J. Kasarskis, Derek Dagostino, Patrick D. Yeramian, Colin Quinn, Rebecca Randall, Lindsay Pothier, James Wymer, Hong Yu, Gale Kittle, Newman Knowlton, Michelle McGovern, Shafeeq Ladha, Jason Walker, Jeffrey D. Rothstein, Adam Quick, James Chan, Kent L. Leslie, Prasha Vigneswaran, Maria E. St. Pierre, Kristin M. Johnson, Walter Gilbert, Namita Goyal, James B. Caress, Marianne Chase, Sabrina Paganoni, Jonathan D. Glass, Justin Klee, Merit Cudkowicz, Jeremy M. Shefner, Suzanne Hendrix, Carlayne E. Jackson, Margaret Owegi, James D. Berry, David A. Schoenfeld, Alexander Sherman, Stephen A. Goutman, Matthew Eydinov, Andrea Swenson, Samuel Maiser
Publikováno v:
Muscle & Nerve
An orally administered, fixed‐dose coformulation of sodium phenylbutyrate‐taurursodiol (PB‐TURSO) significantly slowed functional decline in a randomized, placebo‐controlled, phase 2 trial in ALS (CENTAUR). Herein we report results of a long
Autor:
Sabrina, Paganoni, Fabiola, De Marchi, James, Chan, Sara K, Thrower, Nathan P, Staff, Neil, Datta, Yaz Y, Kisanuki, Vivian, Drory, Christina, Fournier, Erik P, Pioro, Stephen A, Goutman, Nazem, Atassi, Maryangel, Jeon, Sarah, Caldwell, Timothy, Mcdonough, Caroline, Gentile, Jianing, Liu, Michelle, Turner, Carol, Denny, Kevin, Felice, Misty, Green, Stephanie, Scarberry, Saad, Abu-Saleh, Beatrice, Nefussy, Debbie, Hastings, Sangri, Kim, Blake, Swihart, Ximena, Arcila-Londono, Daniel S, Newman, Michael, Silverman, Angela, Genge, Kristiana, Salmon, Lauren, Elman, Leo, Mccluskey, Kelly, Almasy, Marc, Gotkine, Kimberly, Goslin, Arlena, Cummings, Eli K, Edwards, Michael, Rivner, Kristy, Bouchard, Brandy, Quarles, Justin, Kwan, Matthew, Jaffa, Robert, Baloh, Peggy, Allred, David, Walk, Samuel, Maiser, Georgios, Manousakis, Valerie, Ferment, J Americo M, Fernandes, Pariwat, Thaisetthawatkul, Deborah, Heimes, Melissa, Phillips, Laura, Sams, Melissa, Kahler, Alecia, Corcoran, Daniel G, Larriviere, Sadie, Chotto, Gracy, Juba
Publikováno v:
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 21:74-81
Primary lateral sclerosis (PLS) is a neurodegenerative disease characterized by progressive upper motor neuron dysfunction. Because PLS patients represent only 1 to 4% of patients with adult motor neuron diseases, there is limited information about t
Autor:
Elizabeth Pedowitz, Luqi Chi, Joss C Cohen, Ambereen K. Mehta, Elyse A. Everett, Samuel Maiser, Jessica Besbris, Christopher A Jones
Publikováno v:
Journal of Palliative Medicine. 23:842-847
Amyotrophic lateral sclerosis (ALS) is a rapidly progressive and fatal neurodegenerative disorder with enormous palliative care (PC) needs that begin at the time of diagnosis. Although it is an uncommon disease, clinicians who work in PC or hospice a
Autor:
Namita Goyal, Nathan P. Staff, Malath Makhay, Bjorn Oskarsson, Seiichi Yasui, Richard Bedlack, Emelia Klonowski, John Turnbull, Nicholas J. Maragakis, Benjamin Rix Brooks, Jenny A Meyer, Kazuko Matsuda, Lorne Zinman, Cynthia Bodkin, Nicholas Olney, Samuel Maiser, Angela Genge
Publikováno v:
Neurodegenerative disease management. 11(6)
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with motor neuron loss as a defining feature. Despite significant effort, therapeutic breakthroughs have been modest. MN-166 (ibudilast) has demonstrated neuroprotective action by var
Autor:
Colin Quinn, Corey T. McMillan, Adam C. Naj, David J. Irwin, Andrea Swenson, John Ravits, Leo McCluskey, John Q. Trojanowski, Jeffrey Statland, Evadnie Rampersaud, J. Paul Taylor, Philip A. Cook, Rosa Rademakers, Michael Benatar, Joanne Wuu, James C. Gee, Ted M. Burns, Gang Wu, Yuen T. So, James Caress, Edward B. Lee, David Walk, Wenan Chen, Katerina Placek, Erik P. Pioro, Laura Hennessy, Lauren Elman, Murray Grossman, J. S. Katz, Volkan Granit, Samuel Maiser, Jin Sha, Carlayne E. Jackson, Vivianna M. Van Deerlin
Publikováno v:
EMBO molecular medicine
EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 13, Iss 1, Pp n/a-n/a (2021)
EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 13, Iss 1, Pp n/a-n/a (2021)
Amyotrophic lateral sclerosis (ALS) is a multi‐system disease characterized primarily by progressive muscle weakness. Cognitive dysfunction is commonly observed in patients; however, factors influencing risk for cognitive dysfunction remain elusive