Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Samuel M. Pope"'
Autor:
Samuel M. Pope, Cecilia Lässer
Publikováno v:
Journal of Extracellular Vesicles, Vol 2, Iss 0, Pp 1-8 (2013)
Background: Until recently thought to be of little significance unless occurring during pregnancy, Toxoplasma gondii infection of human hosts is now known to play a larger role in mental health and is a growing concern in the health care community. W
Externí odkaz:
https://doaj.org/article/887f268b7e7a437dac98f1d3590a676c
Autor:
Samuel M. Pope
Publikováno v:
Disaster medicine and public health preparedness. 11(2)
The purpose of this communication is to explore the implications of genome editing techniques, such as CRISPR/Cas9, on public health–related responses to outbreaks of disease. The recent commercialization of genome editing techniques makes the crea
Autor:
Emily E. Muntel, Yoshihiro Yamada, Marc E. Rothenberg, Samuel M. Pope, Simon P. Hogan, Eric B. Brandt, Nives Zimmermann, Anil Mishra
Publikováno v:
Clinical Experimental Allergy. 36:543-553
Background Of the numerous adhesion molecules expressed by eosinophils, the alpha4-integrin has been identified as critically involved in eosinophil trafficking in the lung. Most studies have focused on the role of the alpha4beta1-adhesion complex, b
Publikováno v:
The Journal of Immunology. 175:5341-5350
The eotaxin chemokines have been implicated in allergen-induced eosinophil responses in the lung. However, the individual and combined contribution of each of the individual eotaxins is not well defined. We aimed to examine the consequences of geneti
Autor:
Patricia C. Fulkerson, Nina E. King, Keith F. Stringer, Samuel M. Pope, Matthew P. Doepker, David P. Witte, Anil Mishra, Nikolaos M. Nikolaidis, Fred D. Finkelman, Eric B. Brandt, Marc E. Rothenberg, Marsha Wills-Karp, Nives Zimmermann
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 32:428-435
Asthma is a complex inflammatory pulmonary disorder that is on the rise despite intense ongoing research. We aimed to elucidate novel pathways involved in the pathogenesis of asthma. Employing asthma models induced by different allergens (ovalbumin a
Autor:
Marc E. Rothenberg, David P. Witte, Patricia C. Fulkerson, Nikolaos M. Nikolaidis, Samuel M. Pope, Nives Zimmermann, Anil Mishra, Nina E. King
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 31:257-265
Asthma, a complex chronic inflammatory pulmonary disorder, is on the rise despite intense ongoing research. To elucidate novel pathways involved in asthma pathogenesis, we used transcript expression profiling in a murine model of asthma. Employing as
Autor:
Anil Mishra, Paul S. Foster, Simon P. Hogan, Eric B. Brandt, Michael P. Royalty, Nives Zimmermann, Marc E. Rothenberg, Samuel M. Pope
Publikováno v:
Nature Immunology. 2:353-360
Although eosinophils have been implicated in the pathogenesis of gastrointestinal disorders, their function has not been established. Using a murine model of oral antigen-induced eosinophil-associated gastrointestinal disease, we report the pathologi
Autor:
Hiroko Saito Akei, Patricia C. Fulkerson, Nikolaos M. Nikolaidis, Jeffery D. Molkentin, Samuel M. Pope, Carine Blanchard, Marc E. Rothenberg, Nives Zimmermann
Publikováno v:
The Journal of biological chemistry. 280(14)
Pulmonary eosinophilia, a hallmark pathologic feature of allergic lung disease, is regulated by interleukin-13 (IL-13) as well as the eotaxin chemokines, but the specific role of these cytokines and their cooperative interaction are only partially un
Autor:
Anil Mishra, Nives Zimmermann, Marc E. Rothenberg, Samuel M. Pope, Nina E. King, Nikolaos M. Nikolaidis, Fred D. Finkelman
Publikováno v:
American journal of respiratory cell and molecular biology. 29(4)
Asthma, a complex chronic inflammatory pulmonary disorder, is on the rise despite intense ongoing research, underscoring the need for new scientific inquiry. In an effort to provide unbiased insight into the pathogenesis of this disease, we took an e
Autor:
Marc E. Rothenberg, Anil Mishra, Simon P. Hogan, Eric B. Brandt, Klaus I. Matthaei, Samuel M. Pope, Nives Zimmermann, Paul S. Foster
Publikováno v:
ResearcherID
Background: IL-13 induces several characteristic features of asthma, including airway eosinophilia, airway hyperresponsiveness, and mucus overproduction; however, the mechanisms involved are largely unknown. Objective: We hypothesized that IL-13–in