Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Samuel M Wu"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
IntroductionMechanical sensitive channels expressed in mammalian retinas are effectors of elevated pressure stresses, but it is unclear how their activation affects visual function in pressure-related retinal disorders.MethodsThis study investigated
Externí odkaz:
https://doaj.org/article/ff8fe0f511fa4a8db6a09e3669c2357a
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
A chemical synapse is either an action potential (AP) synapse or a graded potential (GP) synapse but not both. This study investigated how signals passed the glutamatergic synapse between the rod photoreceptor and its postsynaptic hyperpolarizing bip
Externí odkaz:
https://doaj.org/article/682c0cc97e7d411ca02053a9f47fe5b8
Publikováno v:
International Journal of Ophthalmology, Vol 10, Iss 9, Pp 1361-1369 (2017)
AIM: To investigate the retinal toxicity and pharmacokinetics of simvastatin intravitreally injected into mice. METHODS: Forty-eight 6-8-week-old C57BL/6J mice were used in this study. Simvastatin was intravitreally injected into the right eye of ea
Externí odkaz:
https://doaj.org/article/bf9d8b76b8d34325ab99da8276607dd0
Autor:
Michela Palmieri, Rituraj Pal, Hemanth R. Nelvagal, Parisa Lotfi, Gary R. Stinnett, Michelle L. Seymour, Arindam Chaudhury, Lakshya Bajaj, Vitaliy V. Bondar, Laura Bremner, Usama Saleem, Dennis Y. Tse, Deepthi Sanagasetti, Samuel M. Wu, Joel R. Neilson, Fred A. Pereira, Robia G. Pautler, George G. Rodney, Jonathan D. Cooper, Marco Sardiello
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-19 (2017)
The transcription factor EB (TFEB) is a master regulator of lysosomal biogenesis. Here authors show that trehalose, an mTOR-independent autophagy inducer, alleviates the pathological phenotypes in a mouse model of neurodegenerative disease. Trehalose
Externí odkaz:
https://doaj.org/article/9d01b8cdb7714197a5184f986c9a6f8a
Publikováno v:
Cells, Vol 10, Iss 6, p 1288 (2021)
(1) Background: High-tension glaucoma damages the peripheral vision dominated by rods. How mechanosensitive channels (MSCs) in the outer retina mediate pressure responses is unclear. (2) Methods: Immunocytochemistry, patch clamp, and channel fluoresc
Externí odkaz:
https://doaj.org/article/f20f405b03ba4616a7f36ccb53f32b79
Autor:
Michela Palmieri, Rituraj Pal, Hemanth R. Nelvagal, Parisa Lotfi, Gary R. Stinnett, Michelle L. Seymour, Arindam Chaudhury, Lakshya Bajaj, Vitaliy V. Bondar, Laura Bremner, Usama Saleem, Dennis Y. Tse, Deepthi Sanagasetti, Samuel M. Wu, Joel R. Neilson, Fred A. Pereira, Robia G. Pautler, George G. Rodney, Jonathan D. Cooper, Marco Sardiello
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-3 (2017)
Nature Communications 8: Article number: 14338 (2017); Published: 6 February 2017; Updated: 13 June 2017 This Article contains errors in Figs 2 and 3, for which we apologize. In Fig. 2c, the four images were inadvertently duplicated from the images i
Externí odkaz:
https://doaj.org/article/ad88932b47944958b842a6eaf7d2a132
Autor:
Samuel M. Wu, Aijun Zhang
Publikováno v:
Vision Research. 186:13-22
Cone photoreceptors are the first neurons along the visual pathway that exhibit center-surround antagonistic receptive fields, the basic building blocks for spatial information processing in the visual system. The surround responses in cones are medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e7c957beb1a9bdb8a25d415390e6165
https://doi.org/10.1016/j.visres.2021.03.013
https://doi.org/10.1016/j.visres.2021.03.013
Autor:
Ryan T. Ash, Ganna Palagina, Jose A. Fernandez-Leon, Jiyoung Park, Rob Seilheimer, Sangkyun Lee, Jasdeep Sabharwal, Fredy Reyes, Jing Wang, Dylan Lu, Muhammad Sarfraz, Emmanouil Froudarakis, Andreas S. Tolias, Samuel M. Wu, Stelios M. Smirnakis
Publikováno v:
J Neurosci
Atypical sensory processing is now thought to be a core feature of the autism spectrum. Influential theories have proposed that both increased and decreased neural response reliability within sensory systems could underlie altered sensory processing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e819ad0a69c05e97d826f69da0ec4a78
https://europepmc.org/articles/PMC9398540/
https://europepmc.org/articles/PMC9398540/
Publikováno v:
Vision Research. 205:108187
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67fe39eae253537e3f321dc1e10c5474
https://doi.org/10.1016/j.visres.2023.108187
https://doi.org/10.1016/j.visres.2023.108187
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience
A chemical synapse is either an action potential (AP) synapse or a graded potential (GP) synapse but not both. This study investigated how signals passed the glutamatergic synapse between the rod photoreceptor and its postsynaptic hyperpolarizing bip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ee6de933fa397a049d9d79cab7b1932
https://doi.org/10.3389/fncel.2021.722533
https://doi.org/10.3389/fncel.2021.722533