Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Samuel M Meier"'
Autor:
Viktoria Pai, Andrea Bileck, Nikolaus Hommer, Patrick Janku, Theresa Lindner, Victoria Kauer, Benedikt Rumpf, Helmuth Haslacher, Gerhard Hagn, Samuel M. Meier-Menches, Leopold Schmetterer, Doreen Schmidl, Christopher Gerner, Gerhard Garhöfer
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The aim of the present study was to investigate retinal microcirculatory and functional metabolic changes in patients after they had recovered from a moderate to severe acute COVID-19 infection. Retinal perfusion was quantified using laser s
Externí odkaz:
https://doaj.org/article/379544e6fa5e4b9d974846a653e524ea
Autor:
Samuel M Meier, Besnik Muqaku, Ronald Ullmann, Andrea Bileck, Dominique Kreutz, Johanna C Mader, Siegfried Knasmüller, Christopher Gerner
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140367 (2015)
Classical drug assays are often confined to single molecules and targeting single pathways. However, it is also desirable to investigate the effects of complex mixtures on complex systems such as living cells including the natural multitude of signal
Externí odkaz:
https://doaj.org/article/453a6e208e864e57941dd32c22891b26
Autor:
Derek Long, Liam Eade, Matthew P. Sullivan, Katharina Dost, Samuel M. Meier-Menches, David C. Goldstone, Christian G. Hartinger, Jörg S. Wicker, Katerina Taškova
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Mass spectrometry (MS) is an analytical technique for molecule identification that can be used for investigating protein-metal complex interactions. Once the MS data is collected, the mass spectra are usually interpreted manually to identify
Externí odkaz:
https://doaj.org/article/4b0d56182a504a0c8b7b8f6d706ad956
Autor:
Dina Baier, Theresa Mendrina, Beatrix Schoenhacker‐Alte, Christine Pirker, Thomas Mohr, Mate Rusz, Benedict Regner, Martin Schaier, Nicolas Sgarioto, Noël J.‐M. Raynal, Karin Nowikovsky, Wolfgang M. Schmidt, Petra Heffeter, Samuel M. Meier‐Menches, Gunda Koellensperger, Bernhard K. Keppler, Walter Berger
Publikováno v:
Advanced Science, Vol 10, Iss 32, Pp n/a-n/a (2023)
Abstract The leading first‐in‐class ruthenium‐complex BOLD‐100 currently undergoes clinical phase‐II anticancer evaluation. Recently, BOLD‐100 is identified as anti‐Warburg compound. The present study shows that also deregulated lipid m
Externí odkaz:
https://doaj.org/article/574893a0a400479184a02dd6ac444ed6
Autor:
Johannes J. Kovarik, Andrea Bileck, Gerhard Hagn, Samuel M. Meier-Menches, Tobias Frey, Anna Kaempf, Marlene Hollenstein, Tarik Shoumariyeh, Lukas Skos, Birgit Reiter, Marlene C. Gerner, Andreas Spannbauer, Ena Hasimbegovic, Doreen Schmidl, Gerhard Garhöfer, Mariann Gyöngyösi, Klaus G. Schmetterer, Christopher Gerner
Publikováno v:
iScience, Vol 26, Iss 1, Pp 105717- (2023)
Summary: To investigate long COVID-19 syndrome (LCS) pathophysiology, we performed an exploratory study with blood plasma derived from three groups: 1) healthy vaccinated individuals without SARS-CoV-2 exposure; 2) asymptomatic recovered patients at
Externí odkaz:
https://doaj.org/article/c79bb1880aec4fe7a52179bead2c26ff
Autor:
Julia Brunmair, Mathias Gotsmy, Laura Niederstaetter, Benjamin Neuditschko, Andrea Bileck, Astrid Slany, Max Lennart Feuerstein, Clemens Langbauer, Lukas Janker, Jürgen Zanghellini, Samuel M. Meier-Menches, Christopher Gerner
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Biomonitoring of sweat from fingertips overcomes current limitations in time-resolved metabolomic profiling of humans and may prove to become a powerful, noninvasive tool for precision medicine. Here, in a feasibility study of short interval sampling
Externí odkaz:
https://doaj.org/article/4fc1196107f94af98aae222ec98214f4
Autor:
Samuel M. Meier-Menches, Benjamin Neuditschko, Lukas Janker, Marlene C. Gerner, Klaus G. Schmetterer, Albrecht Reichle, Christopher Gerner
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Acute promyelocytic leukaemia (APL) can be cured by the co-administration of arsenic trioxide (ATO) and all-trans retinoic acid (ATRA). These small molecules relieve the differentiation blockade of the transformed promyelocytes and trigger their matu
Externí odkaz:
https://doaj.org/article/f9e84bc747254bcea26bd6bbee47c70b
Autor:
Stephan Mokesch, Klaudia Cseh, Heiko Geisler, Michaela Hejl, Matthias H. M. Klose, Alexander Roller, Samuel M. Meier-Menches, Michael A. Jakupec, Wolfgang Kandioller, Bernhard K. Keppler
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
A series of 2-phenylbenzothiazole derivatives and their corresponding organometallic ruthenium(II) and osmium(II) complexes were synthesized, designed to exploit both, the attributes of the half-sandwich transition metal scaffold and the bioactivity
Externí odkaz:
https://doaj.org/article/68571d82c92d4b019aea10e20ae51176
Autor:
Dina Baier, Beatrix Schoenhacker-Alte, Mate Rusz, Christine Pirker, Thomas Mohr, Theresa Mendrina, Dominik Kirchhofer, Samuel M. Meier-Menches, Katharina Hohenwallner, Martin Schaier, Evelyn Rampler, Gunda Koellensperger, Petra Heffeter, Bernhard Keppler, Walter Berger
Publikováno v:
Pharmaceutics, Vol 14, Iss 2, p 238 (2022)
Cellular energy metabolism is reprogrammed in cancer to fuel proliferation. In oncological therapy, treatment resistance remains an obstacle and is frequently linked to metabolic perturbations. Identifying metabolic changes as vulnerabilities opens u
Externí odkaz:
https://doaj.org/article/7c0e455d4c484ce7be28ed3666638e66
Autor:
Benjamin Neuditschko, Marlene Leibetseder, Julia Brunmair, Gerhard Hagn, Lukas Skos, Marlene C. Gerner, Samuel M. Meier-Menches, Iveta Yotova, Christopher Gerner
Publikováno v:
Biomolecules, Vol 11, Iss 8, p 1230 (2021)
Endometriosis is a benign disease affecting one in ten women of reproductive age worldwide. Although the pain level is not correlated to the extent of the disease, it is still one of the cardinal symptoms strongly affecting the patients’ quality of
Externí odkaz:
https://doaj.org/article/c9e693d7fe934bb3a61e451adc56f28a