Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Samuel Luisier"'
Autor:
Samuel Luisier, Christian J. Leumann
Publikováno v:
CHIMIA, Vol 62, Iss 4 (2008)
Two novel bicyclo nucleoside isomers carrying the base thymine in the furanose ring and an ester substituent in the carbocyclic ring were synthesized from a common bicyclic sugar precursor via a cyclopropanation/fragmentation pathway in nine steps. T
Externí odkaz:
https://doaj.org/article/1e3efcd4d3c34626b1768f886cc07934
Autor:
Christian J. Leumann, Samuel Luisier
Publikováno v:
ChemBioChem. 9:2244-2253
The synthesis of two novel pyrimidine bicyclonucleosides (bc(ox)-nucleosides) has been accomplished. These bicyclonucleosides each carry a lipophilic benzyloxime substituent on the carbocyclic ring and show improved conformational similarity to 2'-de
Publikováno v:
ChemInform. 42
An efficient convergent synthesis of human proinsulin by chemical ligation of three synthetic peptide segments is presented.
A convergent synthetic strategy based on modern chemical ligation methods was used to make human proinsulin. The synthetic protein was characterized by LCMS, CD spectroscopy, and by 1D- and 2D-NMR spectroscopy. Synthetic human proinsulin had full bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35e330294c0d30baf899b9bdbe391ca4
https://europepmc.org/articles/PMC3835593/
https://europepmc.org/articles/PMC3835593/
Publikováno v:
Nucleic acids symposium series (2004). (52)
The N-iodosuccinimide (NIS) induced nucleosidation of protected natural bases with bicyclo[3.3.0] sugar precursors was investigated. It was found that this method is particularly suited for the synthesis of N(1)-pyrimidine nucleosides and provides a
Autor:
Christian J. Leumann, Samuel Luisier
Publikováno v:
Luisier, Samuel; Leumann, Christian J. (2008). Synthesis of bicyclo-DNA nucleosides with additional functionalization in the carbocyclic ring. CHIMIA, 62(4), pp. 270-272. Bern: Schweizerische Chemische Gesellschaft 10.2533/chimia.2008.270
CHIMIA, Vol 62, Iss 4 (2008)
CHIMIA, Vol 62, Iss 4 (2008)
Two novel bicyclo nucleoside isomers carrying the base thymine in the furanose ring and an ester substituent in the carbocyclic ring were synthesized from a common bicyclic sugar precursor via a cyclopropanation/fragmentation pathway in nine steps. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c37fc35f8e4e83004090ebc58fff8afa
https://boris.unibe.ch/31037/1/s19.pdf
https://boris.unibe.ch/31037/1/s19.pdf
Autor:
Christian J. Leumann, Samuel Luisier
Publikováno v:
HETEROCYCLES. 82:775
The synthesis of a novel bicyclo-thymidine nucleoside bearing an ester functionality at C(6') (bc(alpha-alk)-nucleosides) is reported. This nucleoside was incorporated into oligodeoxynucleotides via solid phase phosphoramidite chemistry, and the este
Publikováno v:
Chimia; 2023, Vol. 77 Issue 12, pA901-A906, 6p
Publikováno v:
Chemical Communications; Nov2010, Vol. 46 Issue 43, p8075-8092, 18p