Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Samuel Lawn"'
Autor:
Andrew D Campbell, Samuel Lawn, Lynn C McGarry, Heidi C Welch, Bradford W Ozanne, Jim C Norman
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53982 (2013)
Expression of the Rac-guanine nucleotide exchange factor (RacGEF), P-Rex1 is a key determinant of progression to metastasis in a number of human cancers. In accordance with this proposed role in cancer cell invasion and metastasis, we find that ectop
Externí odkaz:
https://doaj.org/article/81340385daf54406a5063cf8a78c1e81
Autor:
Michael G. Brant, Graham A.E. Garnett, Joy Guedia, Manuel Lasalle, Samuel Lawn, Mark E. Petersen, Renee Duan, Jose Mendez-Campos, Truman Hirkala-Schaefer, Geoffrey C. Winters, Stuart D. Barnscher
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. :129348
Autor:
Joanna Pyczek, Bo Young Ahn, Heewon Seo, Samuel Lawn, Shannon Snelling, Katalin Osz, Robyn Flynn, Sorana Morrissy, Jennifer Chan
Publikováno v:
Neuro-Oncology. 24:vii294-vii294
INTRODUCTION Mouse models are instrumental in advancing our understanding of glioblastoma (GBM), however many commonly used models have features that limit their practicality or applicability. These limitations can include an incomplete immune contex
Autor:
Marco A. Marra, Rajiv Dixit, Mana Alshehri, Alexandra D. Rogers, Michael D. Blough, Stephen M. Robbins, Samuel Lawn, Lata Adnani, Jennifer A. Chan, Carol Schuurmans, Shiekh Tanveer Ahmad, Luke Frankiw, Wei Wu, Myra J. Chen, J. Gregory Cairncross
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Nature communications, vol 10, iss 1
Nature communications, vol 10, iss 1
Capicua (Cic) is a transcriptional repressor mutated in the brain cancer oligodendroglioma. Despite its cancer link, little is known of Cic’s function in the brain. We show that nuclear Cic expression is strongest in astrocytes and neurons but weak
Autor:
Patrick J. Cimino, Shazreh Bukhari, Hiba Omairi, Gregory Cairncross, Alexandra Bohm, Cameron J. Grisdale, Jennifer A. Chan, Cindy Chen, Raymond C B Wong, Haley Pedersen, Yaoqing Shen, Lori Maxwell, John Kelly, N. Daniel Berger, Michael D. Blough, Yaping Yu, Steven J.M. Jones, Jessica DePetro, Amanda Gerber, Eric C. Holland, Erin Chahley, V. Wee Yong, Samuel Weiss, Samuel Lawn, Reza Mirzaei, Nicholas Chahley, Carmen Binding, Kaitlin Thomas, Matthaeus Ware
BackgroundImagining ways to prevent or treat glioblastoma (GBM) have been hindered by a lack of understanding of its pathogenesis. Although PDGF-AA overexpression may be an early event, critical details of the core biology are lacking. Existing PDGF-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74bebf32b06aca7bc75919a5a602ee6e
https://doi.org/10.1101/837138
https://doi.org/10.1101/837138
Autor:
Myra J. Chen, Luke Frankiw, Rajiv Dixit, Michael D. Blough, J. Gregory Cairncross, Shiekh Tanveer Ahmad, Wei Wu, Lata Adnani, Stephen M. Robbins, Carol Schuurmans, Samuel Lawn, Mana Alshehri, Alexandra D. Rogers, Jennifer A. Chan
Capicua (Cic) is a transcriptional repressor mutated in the brain cancer oligodendroglioma. Despite its cancer link, little is known of Cic’s function in the brain. Here, we investigated the relationship between Cic expression and cell type specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91e572697c41c0aa36ecad0528801ccc
Autor:
Carol Schuurmans, Jennifer A. Chan, Rajiv Dixit, Gregory Cairncross, Stephen M. Robbins, Samuel Lawn, Alexandra D. Rogers, Lata Adnani, Mana Alshehri, Myra J. Chen, Shiekh Tanveer Ahmad
Publikováno v:
Neuro-Oncology. 18:vi43-vi44
Autor:
Niveditha Krishna, Michelle Fournier, Prakash Chinnaiyan, Philip A. Barker, Samuel Lawn, Michele Zeinieh, J. Gerardo Valadez, Geoffrey T. Gibney, Lisa Potthast, David Fenstermacher, Bruce D. Carter, Michael K. Cooper, Rajappa S. Kenchappa, Peter A. Forsyth, Xiaotao Qu
Publikováno v:
The Journal of biological chemistry. 289(12)
Malignant gliomas are highly invasive, proliferative, and resistant to treatment. Previously, we have shown that p75 neurotrophin receptor (p75NTR) is a novel mediator of invasion of human glioma cells. However, the role of p75NTR in glioma prolifera
Autor:
Deborah M. Kurrasch, Carol Schuurmans, Jennifer A. Chan, Saiqun Li, Samuel Lawn, David D. Eisenstat, Rajiv Dixit, Pierre Mattar, Grey Wilkinson, Cassandra D. Kinch
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 34(6)
Neural cell fate specification is well understood in the embryonic cerebral cortex, where the proneural genesNeurog2andAscl1are key cell fate determinants. What is less well understood is how cellular diversity is generated in brain tumors. Gliomas a
Autor:
Jim C. Norman, Heidi C.E. Welch, Samuel Lawn, Bradford W. Ozanne, Lynn McGarry, Andrew D. Campbell
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 1, p e53982 (2013)
PLoS ONE, Vol 8, Iss 1, p e53982 (2013)
Expression of the Rac-guanine nucleotide exchange factor (RacGEF), P-Rex1 is a key determinant of progression to metastasis in a number of human cancers. In accordance with this proposed role in cancer cell invasion and metastasis, we find that ectop