Výsledky vyhledávání - "Samuel Kasson"

Akademický článek

Selective monitoring of the protein-free ADP-ribose released by ADP-ribosylation reversal enzymes.

Autor: Samuel Kasson, Nuwani Dharmapriya, In-Kwon Kim

Publikováno v: PLoS ONE, Vol 16, Iss 6, p e0254022 (2021)

ADP-ribosylation is a key post-translational modification that regulates a wide variety of cellular stress responses. The ADP-ribosylation cycle is maintained by writers and erasers. For example, poly(ADP-ribosyl)ation cycles consist of two predomina

Externí odkaz: https://doaj.org/article/9340367bbbce459eb9ed7f31ae9848b4

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PARG has a robust endo-glycohydrolase activity that releases protein-free poly(ADP-ribose) chains

Autor: Chris M. W. Ho, Samuel Kasson, Linh Tran, In-Kwon Kim, Sookkyung Lim, Yasin Pourfarjam

Publikováno v: Biochemical and biophysical research communications. 527(3)

Poly(ADP-ribosyl)ation (PARylation) regulates DNA damage response, chromatin structure, and cell-fate. Dynamic regulation of cellular PAR levels is crucial for the maintenance of genomic integrity and excessive cellular PAR activates a PAR-dependent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::994655accbd3201ee21b903151e728e5
https://pubmed.ncbi.nlm.nih.gov/32439163

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