Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Samuel Kantonen"'
Publikováno v:
Biochimica et biophysica acta. General subjects, vol 1862, iss 3
Background In theory, binding enthalpies directly obtained from calorimetry (such as ITC) and the temperature dependence of the binding free energy (van't Hoff method) should agree. However, previous studies have often found them to be discrepant. Me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::071e78dd3e51e088a71db54fc9ab2f1c
https://doi.org/10.1016/j.bbagen.2017.11.020
https://doi.org/10.1016/j.bbagen.2017.11.020
We utilize a previously described Minimal Basis Iterative Stockholder (MBIS) method to carry out an atoms-in-molecules partitioning of electron densities. Information from these atomic densities is then mapped to Lennard-Jones parameters using a set
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::657bc6572aa8b5a041d20854a94ccc41
https://doi.org/10.26434/chemrxiv.9121367.v1
https://doi.org/10.26434/chemrxiv.9121367.v1
Researchers developing software to predict the binding constants of small molecules for proteins have, in recent years, turned to host-guest systems as simple, computationally tractable model systems to test and improve these computational methods. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c22171b9d8b9c1ec6c802958fe8bd40d
https://doi.org/10.26434/chemrxiv.5782224.v1
https://doi.org/10.26434/chemrxiv.5782224.v1
BackgroundIn theory, binding enthalpies directly obtained from calorimetry (such as ITC) and the temperature dependence of the binding free energy (van’t Hoff method) should agree. However, previous studies have often found them to be discrepant.Me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d156fbdf5e8065e8eb8e511d51627616
https://doi.org/10.1101/210351
https://doi.org/10.1101/210351
Publikováno v:
Journal of Leukocyte Biology. 96:779-784
Neutrophils and macrophages are professional phagocytic cells, extremely efficient at the process of engulfing and killing bacteria. Autophagy is a similar process, by which phagosomes recycle internal cell structures during nutrient shortages. Some
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff53a2cef000acfa21b888f911886c6f
https://doi.org/10.1189/jlb.2vmr0214-120rr
https://doi.org/10.1189/jlb.2vmr0214-120rr
Publikováno v:
Biochimica et biophysica acta. General subjects, vol 1861, iss 2
Background Isothermal titration calorimetry (ITC) is uniquely useful for characterizing binding thermodynamics, because it straightforwardly provides both the binding enthalpy and free energy. However, the precision of the results depends on the expe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29c94bf20cca47c8cccb1a749d8865cb
https://europepmc.org/articles/PMC5195854/
https://europepmc.org/articles/PMC5195854/
Autor:
Samuel Kantonen, Madhu Mahankali, Julian Gomez-Cambronero, Dianne Cox, Nathaniel Hatton, Haein Park, Karen M. Henkels
Publikováno v:
Molecular and Cellular Biology. 31:4524-4537
Phagocytosis is a primary innate response of both macrophages and neutrophils involving the formation of filamentous actin (F-actin)-rich protrusions that are extended around opsonized pathogens to form a phagocytic cup, resulting in their subsequent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70812550f7eff1e5926539978f368b16
https://doi.org/10.1128/mcb.05684-11
https://doi.org/10.1128/mcb.05684-11
Publikováno v:
The Journal of biological chemistry. 288(14)
The products of the oncogene Fes and JAK3 are tyrosine kinases, whose expressions are elevated in tumor growth, angiogenesis, and metastasis. Phosphatidic acid, as synthesized by phospholipase D (PLD), enhances cancer cell survival. We report a new s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31b48cbab31eadc6ce73b0951cb19b28
https://pubmed.ncbi.nlm.nih.gov/23404507
https://pubmed.ncbi.nlm.nih.gov/23404507