Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Samuel J. Wadsworth"'
Autor:
Christopher D. Pascoe, Ma’en Obeidat, Bryna A. Arsenault, Yunlong Nie, Stephanie Warner, Dorota Stefanowicz, Samuel J. Wadsworth, Jeremy A. Hirota, S. Jasemine Yang, Delbert R. Dorscheid, Chris Carlsten, Tillie L. Hackett, Chun Y. Seow, Peter D. Paré
Publikováno v:
BMC Pulmonary Medicine, Vol 17, Iss 1, Pp 1-14 (2017)
Abstract Background Gene expression changes in the structural cells of the airways are thought to play a role in the development of asthma and airway hyperresponsiveness. This includes changes to smooth muscle contractile machinery and epithelial bar
Externí odkaz:
https://doaj.org/article/e66410ac5d12451d8dc6921708813749
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 318(5)
The human bronchial epithelium is an important barrier tissue that is damaged or pathologically altered in various acute and chronic respiratory conditions. To represent the epithelial component of respiratory disease, it is essential to use a physio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a8bee94202e7ce310ce3e25f592ae22
https://pubmed.ncbi.nlm.nih.gov/32208929
https://pubmed.ncbi.nlm.nih.gov/32208929
Autor:
Laura De la Vega, Emily Abelseth, Laila Abelseth, Simon Beyer, Samuel J. Wadsworth, Stephanie M. Willerth
Publikováno v:
ACS Biomaterials Science & Engineering. 5:234-243
3D bioprinting offers the opportunity to automate the process of tissue engineering, which combines biomaterial scaffolds and cells to generate substitutes for diseased or damaged tissues. These bioprinting methods construct tissue replacements by po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86d575f9b3680afb744c76fea25db82d
https://doi.org/10.1021/acsbiomaterials.8b01235
https://doi.org/10.1021/acsbiomaterials.8b01235
Autor:
Samuel J. Wadsworth, Christopher D. Pascoe, S. Jasemine Yang, Chun Y. Seow, Ma'en Obeidat, Jeremy A. Hirota, Tillie L. Hackett, Christopher Carlsten, Peter D. Paré, Yunlong Nie, Dorota Stefanowicz, Stephanie M. Warner, Delbert R. Dorscheid, Bryna A. Arsenault
Publikováno v:
BMC Pulmonary Medicine, Vol 17, Iss 1, Pp 1-14 (2017)
BMC Pulmonary Medicine
BMC Pulmonary Medicine
Background Gene expression changes in the structural cells of the airways are thought to play a role in the development of asthma and airway hyperresponsiveness. This includes changes to smooth muscle contractile machinery and epithelial barrier inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43fa55363886606303490abaa15bc3d7
http://link.springer.com/article/10.1186/s12890-017-0545-9
http://link.springer.com/article/10.1186/s12890-017-0545-9
Publikováno v:
Current Allergy and Asthma Reports. 13:118-129
Human beings come in all shapes and sizes. Heterogeneity makes life interesting, but leads to inter-individual variation in disease susceptibility and response to therapy. One major health challenge is to develop "personalised medicine"; therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57b17d508371e9f3f7abf9458d1ffe3f
https://doi.org/10.1007/s11882-012-0325-9
https://doi.org/10.1007/s11882-012-0325-9
Publikováno v:
Respirology. 16:22-33
For translational respiratory research including in the development of clinical diagnostic tools, a minimally invasive imaging method, which can provide both cellular and extracellular structural details with sufficient specificity, sensitivity and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3711baec09f3c4d97718212fc286cb3
https://doi.org/10.1111/j.1440-1843.2010.01898.x
https://doi.org/10.1111/j.1440-1843.2010.01898.x
Autor:
A. Gordon Robertson, Laurent Devel, David Marchant, Dimitris Georgiadis, Julie Ng, David J. Granville, Honglin Luo, Georgina S. Butler, Michael J Norris, Karl Heilbron, Zongshu Luo, Taylor Bucyk, Vincent Dive, Lisa S. Ang, Bruce M. McManus, Wenming Duan, Christopher M. Overall, Samuel J. Wadsworth, Reid G. Hendry, Caroline Cheung, Theo J. Moraes, Andrei Karpov, Leanne M. Bilawchuk, Caroline L. Bellac, Antoine Dufour, Richard G. Hegele
Publikováno v:
Nature medicine. 20(5)
Interferon-α (IFN-α) is essential for antiviral immunity, but in the absence of matrix metalloproteinase-12 (MMP-12) or IκBα (encoded by NFKBIA) we show that IFN-α is retained in the cytosol of virus-infected cells and is not secreted. Our findi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c22eb0f52c77ff9dc075839e9b4195f1
https://pubmed.ncbi.nlm.nih.gov/24804752
https://pubmed.ncbi.nlm.nih.gov/24804752
Pulmonary function tests (PFTs/spirometry) are routinely used clinically to diagnose asthma. Forced expiratory volume in one second (FEV1) is a measure of airflow and is influenced largely by the resistance in the airways. During an “asthma attack
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bc6533081bd6364743e39d7d418f39a
https://doi.org/10.5772/51970
https://doi.org/10.5772/51970
Publikováno v:
Pulmonary pharmacologytherapeutics. 25(6)
While allergies are very common, affecting ∼40% of the population in most Western countries, only a proportion of allergic people develop asthma. This highlights the importance of tissue and cell specific mechanisms that contribute to the disease.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d47502fe31398da82933f4a7e014a5d
https://pubmed.ncbi.nlm.nih.gov/23022283
https://pubmed.ncbi.nlm.nih.gov/23022283
Autor:
David R. Marchant, Theo J. Moraes, Farnoosh Tayyari, Samuel J. Wadsworth, Peter Mastrangelo, Richard G. Hegele
Publikováno v:
D36. INFLUENCES AND OUTCOMES OF RESPIRATORY VIRAL INFECTIONS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38e70f66d59563dd5095213c35aa8109
https://doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a6880
https://doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a6880