Zobrazeno 1 - 10 of 28 pro vyhledávání: '"Samuel J. Roberts"'
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Akademický článek
Selective prebiotic conversion of pyrimidine and purine anhydronucleosides into Watson-Crick base-pairing arabino-furanosyl nucleosides in water
Autor: Samuel J. Roberts, Rafał Szabla, Zoe R. Todd, Shaun Stairs, Dejan-Krešimir Bučar, Jiří Šponer, Dimitar D. Sasselov, Matthew W. Powner
Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Arabinonucleic acid (ANA) Watson-Crick base-pair with RNA/DNA and can evolve to display enzyme-like function. Here, the authors now identify a prebiotic pathway that yields the complete set of Watson-Crick base-pairing purine and pyrimidine ANA nucle
Externí odkaz: https://doaj.org/article/455de6701d6f41b6b2ff842b73e5e635
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2
Triplet-encoded prebiotic RNA aminoacylation
Autor: Meng Su, Christian Schmitt, Ziwei Liu, Samuel J. Roberts, Kim C. Liu, Konstantin Röder, Andres Jäschke, David J. Wales, John D. Sutherland
The encoding step of translation involves attachment of amino acids to cognate tRNAs by aminoacyl-tRNA synthetases, themselves the product of coded peptide synthesis. So, the question arises — before these enzymes evolved, how were primordial tRNAs
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::82512090fca18f5343c10deb1eb1d7d0
https://doi.org/10.1101/2023.03.13.532408
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3
Potentially Prebiotic Synthesis of Aminoacyl-RNA via a Bridging Phosphoramidate-Ester Intermediate
Autor: Samuel J. Roberts, Ziwei Liu, John D. Sutherland
Publikováno v: Journal of the American Chemical Society. 144:4254-4259
Translation according to the genetic code is made possible by selectivity both in aminoacylation of tRNA and in anticodon:codon recognition. In extant biology, tRNAs are selectively aminoacylated by enzymes using high-energy intermediates, but how th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::812c2779d4788e717e3c7ed2f092bd95
https://doi.org/10.1021/jacs.2c00772
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5
Template-Free Assembly of Functional RNAs by Loop-Closing Ligation
Autor: Long-Fei Wu, Ziwei Liu, Samuel J. Roberts, Meng Su, Jack W. Szostak, John D. Sutherland
Publikováno v: Journal of the American Chemical Society. 144(30)
The first ribozymes are thought to have emerged at a time when RNA replication proceeded via nonenzymatic template copying processes. However, functional RNAs have stable folded structures, and such structures are much more difficult to copy than sho
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1ea5e06ab48987850d9ea3af23ac309
https://pubmed.ncbi.nlm.nih.gov/35880790
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6
Akademický článek
A framework for test measurement selection in athlete physical preparation
Autor: Lachlan P. James, Jade A. Z. Haycraft, David L. Carey, Samuel J. Robertson
Publikováno v: Frontiers in Sports and Active Living, Vol 6 (2024)
Preparing athletes for competition requires the diagnosis and monitoring of relevant physical qualities (e.g., strength, power, speed, endurance characteristics). Decisions regarding test selection that attempt to measure these physical attributes ar
Externí odkaz: https://doaj.org/article/c83e6e789e244b5cbe24f657dd3243a4
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7
Photostability of oxazoline RNA-precursors in UV-rich prebiotic environments
Autor: Rafał Szabla, Robert W. Góra, Matthew W. Powner, Mikołaj J. Janicki, Jiří Šponer, Samuel J. Roberts
Publikováno v: Chemical Communications. 54:13407-13410
Pentose aminooxazolines and oxazolidinone thiones are considered as the key precursors which could have enabled the formation of RNA nucleotides under the conditions of early Earth. UV-irradiation experiments and quantum-chemical calculations demonst
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9abb3583fce9fbab6cda84d0ff413018
https://doi.org/10.1039/c8cc07343k
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