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pro vyhledávání: '"Samuel J. Hoare"'
Autor:
Graham Beaton, Aixia Sun, Jason Haelewyn, Susan K. Sullivan, Wilna J. Moree, Michael P. Hedrick, Mark Santos, Margaret J. Bradbury, Jenny Wen, Jinghua Yu, Said Zamani-Kord, Coon Timothy Richard, Paul D. Crowe, Lisa M. Hernández, Siobhan Malany, Robert E. Petroski, Bin-Feng Li, Samuel J. Hoare
Publikováno v:
Bioorganicmedicinal chemistry letters. 19(15)
The benzimidazole core of the selective non-brain-penetrating H 1 -antihistamine mizolastine was used to identify a series of brain-penetrating H 1 -antihistamines for the potential treatment of insomnia. Using cassette PK studies, brain-penetrating