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pro vyhledávání: '"Samuel J. Bunce"'
Autor:
Carol K. Hall, Sheena E. Radford, Andrew J. Wilson, Yiming Wang, Stefan Auer, Samuel J. Bunce
Publikováno v:
Proceedings of the National Academy of Sciences. 116:2091-2096
The aggregation of monomeric amyloid β protein (Aβ) peptide into oligomers and amyloid fibrils in the mammalian brain is associated with Alzheimer’s disease. Insight into the thermodynamic stability of the Aβ peptide in different polymeric state
Publikováno v:
Aiche Journal. American Institute of Chemical Engineers
Determining the structure of the (oligomeric) intermediates that form during the self‐assembly of amyloidogenic peptides is challenging because of their heterogeneous and dynamic nature. Thus, there is need for methodology to analyze the underlying