Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Samuel J Goldman"'
Autor:
Unnur S Bjornsdottir, Stephen T Holgate, Padmalatha S Reddy, Andrew A Hill, Charlotte M McKee, Cristina I Csimma, Amy A Weaver, Holly M Legault, Clayton G Small, Renee C Ramsey, Debra K Ellis, Conor M Burke, Philip J Thompson, Peter H Howarth, Andrew J Wardlaw, Phillip G Bardin, David I Bernstein, Louis B Irving, Geoffrey L Chupp, George W Bensch, Gregory W Bensch, Jon E Stahlman, Monroe Karetzky, James W Baker, Rachel L Miller, Brad H Goodman, Donald G Raible, Samuel J Goldman, Douglas K Miller, John L Ryan, Andrew J Dorner, Frederick W Immermann, Margot O'Toole
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21902 (2011)
Asthma exacerbations remain a major unmet clinical need. The difficulty in obtaining airway tissue and bronchoalveolar lavage samples during exacerbations has greatly hampered study of naturally occurring exacerbations. This study was conducted to de
Externí odkaz:
https://doaj.org/article/f4ed057e1067408a9023f1d201f1a2b4
Autor:
Ryan Thompson, Philip L. Reno, Samuel J. Goldman, Sabrina Kistler, Kelsey M Kjosness, Avani Bhavsar, Emily Schuetz
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2e92332a1c49a5e31fa41a5cf47c2f3
https://doi.org/10.1096/fasebj.2021.35.s1.03152
https://doi.org/10.1096/fasebj.2021.35.s1.03152
Autor:
Nicholas Stephens, Emily Schuetz, Sabrina Kistler, Timothy M. Ryan, Philip L. Reno, Samuel J. Goldman, Kelsey M Kjosness, Avani Bhavsar
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0b23d4eb635acd8b4d742d3ccb3ffb7
https://doi.org/10.1096/fasebj.2021.35.s1.03175
https://doi.org/10.1096/fasebj.2021.35.s1.03175
Autor:
Peter B. Stathopulos, Toby P. Thomas, Jianhe Huang, Shrishiv A. Timbalia, Santhanam Shanmughapriya, Jeffrey L. Caplan, Daniel P. Corbally, Alexander Dietrich, Xue-Qian Zhang, Vishal M. Gohil, Neeharika Nemani, Sarah L. Breves, Fabián Jaña, Sarah M. Schumacher, Samuel J. Goldman, Rexford S. Ahima, Zhiwei Dong, Allison R. Cutri, Dhanendra Tomar, Joseph Y. Cheung, Joseph E. Rabinowitz, Steven R. Houser, Salim Merali, Joseph P. Fairweather, Michael E. Rockman, Jianliang Song, Nicholas E. Hoffman, Carlos A. Barrero, Sudarsan Rajan, Diana A. Koch, Muniswamy Madesh, Timothy S. Luongo, Walter J. Koch, John W. Elrod, Vickas V. Patel
Publikováno v:
Cell Reports, Vol 15, Iss 8, Pp 1673-1685 (2016)
Mitochondrial Ca(2+) Uniporter (MCU)-dependent mitochondrial Ca(2+) uptake is the primary mechanism for increasing matrix Ca(2+) in most cell types. However, a limited understanding of the MCU complex assembly impedes the comprehension of the precise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6807656a459a4b24da7690ec3172054a
https://europepmc.org/articles/PMC4880542/
https://europepmc.org/articles/PMC4880542/
Altered regulation of aquaporin gene expression in allergen and IL-13-induced mouse models of asthma
Autor:
Divya Chaudhary, Marion T. Kasaian, Cara M. M. Williams, Casey A. McDonald, Melisa W.-Y. Ho, Bijia Deng, Stephen Pazdziorko, Carissa M. Krane, Samuel J. Goldman, Lawrence Mason, Venkateshwar Mutyam
Publikováno v:
Cytokine. 46:111-118
IL-13 is known to affect many processes that contribute to an asthmatic phenotype, including inflammation, fibrosis, and mucus production. Members of the aquaporin (AQP) family of transmembrane water channels are targets of regulation in models of lu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b9bf477e537ad3d8cfa750322f9a3b0
https://doi.org/10.1016/j.cyto.2008.12.018
https://doi.org/10.1016/j.cyto.2008.12.018
Publikováno v:
Journal of Leukocyte Biology. 83:1267-1276
Protein kinase C theta (PKCtheta) is expressed in NK cells, but its functional role has not been defined. Here, we demonstrate involvement of PKCtheta in IL-12-induced NK cell IFN-gamma production. NK cells from PKCtheta(-/-) mice produced less IFN-g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f9476ebbbbeaedd2a685a1e690c2a64
https://doi.org/10.1189/jlb.1107745
https://doi.org/10.1189/jlb.1107745
Autor:
Samuel J. Goldman, Kyriaki Dunussi-Joannopoulos, Jill F. Wright, Riyez Karim, Lynette A. Fouser, Frann Bennett, Mary Collins, Matthew J. Whitters, Cara M. M. Williams, Spencer Liang, Andrew J. Long
Publikováno v:
The Journal of Immunology. 179:7791-7799
IL-17A and IL-17F are related homodimeric proteins of the IL-17 family produced by Th17 cells. In this study, we show that mouse Th17 cells also produce an IL-17F/A heterodimeric protein. Whereas naive CD4+ T cells differentiating toward the Th17 cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d19c998dea8146e0370b73c7873df0f5
https://doi.org/10.4049/jimmunol.179.11.7791
https://doi.org/10.4049/jimmunol.179.11.7791
Autor:
Kimberly Ann Marquette, Joseph P. Sypek, Rustem Krykbaev, Michael D Wadanoli, Franklin J. Schlerman, Marion T. Kasaian, Suresh Vunnum, Wood Nancy L, Bruce A. Jacobson, Lioudmila Tchistiakova, Andrea G Bree, Timothy A. Cook, Xin Xu, Xiang-Yang Tan, Samuel J. Goldman, Angela Widom, Debra D. Donaldson
Publikováno v:
Journal of Allergy and Clinical Immunology. 119:1251-1257
Background Airway inflammation is a hallmark feature of asthma and a driver of airway hyperresponsiveness. IL-13 is a key inducer of airway inflammation in rodent models of respiratory disease, but a role for IL-13 has not been demonstrated in primat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82f22fd41ec804b9e3b31d0b9ca5da3e
https://doi.org/10.1016/j.jaci.2007.02.009
https://doi.org/10.1016/j.jaci.2007.02.009
Autor:
Anthony Barry, Ashfaq Ahmed, Lioudmila Tchistiakova, Bruce A. Jacobson, Timothy A. Cook, Debra D. Donaldson, Kimberly Ann Marquette, Samuel J. Goldman, Xin Xu, Angela Widom, Xiang Yang Tan, William M. Abraham, Marion T. Kasaian
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 36:368-376
IL-13 contributes to airway hyperresponsiveness, mucus secretion, inflammation, and fibrosis, suggesting that it plays a central role in asthma pathogenesis. Neutralization of IL-13 with sIL-13Ralpha2-Fc (sIL-13R) reduces allergen-induced airway resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62a2d19b8e8b3fb34481add971d16c84
https://doi.org/10.1165/rcmb.2006-0244oc
https://doi.org/10.1165/rcmb.2006-0244oc
Autor:
Samuel J. Goldman, Aiping Jiao, Scott H. Schelling, Cara Williams, Susan Fish, Lawrence Mason
Publikováno v:
Annals of Allergy, Asthma & Immunology. 98:83-88
Background Several studies indicate that selectin-mediated leukocyte migration may depend on the types of initiating inflammatory stimuli or on the vascular beds involved in the inflammatory response. Thus, targeting selectin interactions to treat in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c4ee9b378d1a175c8bc89724f18da0b
https://doi.org/10.1016/s1081-1206(10)60864-2
https://doi.org/10.1016/s1081-1206(10)60864-2